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St. Jude researchers uncover NLRC5's role in immune response and cell death

The innate immune system is responsible for protecting the human body from threats that could cause disease or infection.

14 Jun 2024

Research points to a potential approach to mitigating diabetes risk from antipsychotic medications

New University of Pittsburgh research points to a potential approach to reducing the risk of diabetes associated with widely prescribed antipsychotic medications.

13 Jun 2024

New research finds a way to delay vitamin B6 degradation

A low vitamin B6 level has negative effects on brain performance. A research team from Würzburg University Medicine has now found a way to delay the degradation of the vitamin.

13 Jun 2024

From Discovery Biology to ELRIG Chair: A Conversation with Melanie Leveridge

In this interview, we speak with Melanie Leveridge, Vice President of Discovery Biology at AstraZeneca and Chair of the Board for ELRIG UK, to discuss her extensive career in the pharmaceutical industry, her role in fostering scientific innovation, and her vision for ELRIG's future.

From ELRIG (UK) Ltd. 13 Jun 2024

New AARF-D award supports Temple researchers to explore synapse function in the aging brain

Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia.

12 Jun 2024

Enhancing CAR-T cell therapy with biodegradable scaffolds

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway.

12 Jun 2024

Researchers engineer water-soluble histidine kinase for enhanced antibiotic drug screens

A bacterial enzyme called histidine kinase is a promising target for new classes of antibiotics. However, it has been difficult to develop drugs that target this enzyme, because it is a "hydrophobic" protein that loses its structure once removed from its normal location in the cell membrane.

11 Jun 2024

Johns Hopkins researchers discover how epilepsy drug modulates brain activity

By super cooling a molecule on the surface of brain cells down to about minus 180 degrees Celsius -; nearly twice as cold as the coldest places in Antarctica -; scientists at Johns Hopkins Medicine say they have determined how a widely-used epilepsy drug works to dampen the excitability of brain cells and help to control, although not cure, seizures.

10 Jun 2024

Transplanted gut microbes from aged mice trigger inflammation in young germ-free mice

When scientists transplanted the gut microbes of aged mice into young "germ-free" mice -; raised to have no gut microbes of their own -; the recipient mice experienced an increase in inflammation that parallels inflammatory processes associated with aging in humans.

10 Jun 2024

CSHL team identifies crucial protein interactions in RNA splicing process

Bodybuilders and cellular mechanisms agree generating protein is a heavy lift. To complete the task, cells rely on complexes called spliceosomes.

10 Jun 2024

Unveiling Pseudomonas aeruginosa's lung invasion tactics with human lung microtissues

How do pathogens invade the lungs? Using human lung microtissues, a team at the Biozentrum of the University of Basel has uncovered the strategy used by a dangerous pathogen.

10 Jun 2024

Glowing marker dye gives medics a 'second pair of eyes' during prostate cancer surgery

A glowing marker dye that sticks to prostate cancer cells could help surgeons to remove them in real-time, according to a study funded by Cancer Research UK.

10 Jun 2024

Critical role of protein-lipid interactions in mitochondrial energy production revealed

By studying mutations in yeast and human cells, Johns Hopkins Medicine scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.

7 Jun 2024

Simple peptide modification could unlock a whole class of targets for drug discovery

A relatively simple peptide modification could unlock a whole class of targets for drug discovery, new research shows.

7 Jun 2024

New approach reduces the required drug dosage for cancer treatment

Traditional chemotherapy often poses significant challenges, including severe side effects, damage to healthy tissue and limited efficacy.

6 Jun 2024

Injectable fish oil emulsion reduces brain damage in newborn rodents

An injectable emulsion containing two omega-3 fatty acids found in fish oil markedly reduced brain damage in newborn rodents after a disruption in the flow of oxygen to the brain near birth, a study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

6 Jun 2024

Molecule News and Research

St. Jude researchers uncover NLRC5's role in immune response and cell death

Research points to a potential approach to mitigating diabetes risk from antipsychotic medications

New research finds a way to delay vitamin B6 degradation

From Discovery Biology to ELRIG Chair: A Conversation with Melanie Leveridge

New AARF-D award supports Temple researchers to explore synapse function in the aging brain

Enhancing CAR-T cell therapy with biodegradable scaffolds

Researchers engineer water-soluble histidine kinase for enhanced antibiotic drug screens

Johns Hopkins researchers discover how epilepsy drug modulates brain activity

Transplanted gut microbes from aged mice trigger inflammation in young germ-free mice

CSHL team identifies crucial protein interactions in RNA splicing process

Unveiling Pseudomonas aeruginosa's lung invasion tactics with human lung microtissues

Glowing marker dye gives medics a 'second pair of eyes' during prostate cancer surgery

Critical role of protein-lipid interactions in mitochondrial energy production revealed

Simple peptide modification could unlock a whole class of targets for drug discovery

New approach reduces the required drug dosage for cancer treatment

Injectable fish oil emulsion reduces brain damage in newborn rodents

Researchers identify a potential metabolic target for cancer immunotherapy

Developing pre-symptomatic diagnostic tools for Alzheimer's disease using long-read RNA sequencing

Oral insulin drops offer needle-free alternative for diabetes management

Mediterranean dietary adherence can reduce mortality risk in women

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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