Monoclonal Antibody News and Research

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Monoclonal antibodies (MAbs) are produced from a single B cell clone and can bind to a single type of antigen binding site. MAbs are homogenous antibodies that cannot form lattices with monomeric proteins as they can bind to only a single epitope on the antigen. Developed in the 1970s, MAbs can be produced against any given substance. Thus they can be used to detect and purify any substance of interest. This has made MAbs a powerful tool of molecular biology, biochemistry, and medicine.
New antibody shows promise as universal weapon against COVID-19 variants

New antibody shows promise as universal weapon against COVID-19 variants

RNA-based therapy shows promise in reducing cholesterol and triglycerides

RNA-based therapy shows promise in reducing cholesterol and triglycerides

Evolving treatment paradigms in multiple myeloma could improve patient outcomes

Evolving treatment paradigms in multiple myeloma could improve patient outcomes

Dupilumab shows promise in cutting COPD flare-ups and boosting lung function

Dupilumab shows promise in cutting COPD flare-ups and boosting lung function

Dupilumab shows promising results in Phase 3 trial for COPD with type 2 inflammation

Dupilumab shows promising results in Phase 3 trial for COPD with type 2 inflammation

FDA-approved TIVDAK®: Targeting tissue factor in cervical cancer

FDA-approved TIVDAK®: Targeting tissue factor in cervical cancer

Enhancing the ability of natural killer cells to combat hematologic malignancies

Enhancing the ability of natural killer cells to combat hematologic malignancies

Novel bispecific antibodies show promise against evolving SARS-CoV-2 variants

Novel bispecific antibodies show promise against evolving SARS-CoV-2 variants

Researchers enhance CAR-T cells to target solid tumors

Researchers enhance CAR-T cells to target solid tumors

Janssen-Cilag seeks European approval for guselkumab in ulcerative colitis and Crohn’s disease treatment

Janssen-Cilag seeks European approval for guselkumab in ulcerative colitis and Crohn’s disease treatment

New monoclonal antibody vaccine slashes malaria risk in children

New monoclonal antibody vaccine slashes malaria risk in children

Experimental monoclonal antibody prevents and reverses clinical type 1 diabetes in mice

Experimental monoclonal antibody prevents and reverses clinical type 1 diabetes in mice

Single dose of malaria monoclonal antibody 77% effective in children, trial in Mali shows

Single dose of malaria monoclonal antibody 77% effective in children, trial in Mali shows

Analysis finds significant variations in national COVID-19 treatment recommendations

Analysis finds significant variations in national COVID-19 treatment recommendations

Study identifies potential strategy to diminish the devastating impacts of traumatic brain injuries

Study identifies potential strategy to diminish the devastating impacts of traumatic brain injuries

Monoclonal antibody Prasinezumab shows promise in slowing rapid Parkinson's progression

Monoclonal antibody Prasinezumab shows promise in slowing rapid Parkinson's progression

Research highlights emergence of immune-evasive SARS-CoV-2 variants in immunocompromised patients

Research highlights emergence of immune-evasive SARS-CoV-2 variants in immunocompromised patients

Three early-phase clinical studies show promising initial data for patients with lymphoma, gastric cancers

Three early-phase clinical studies show promising initial data for patients with lymphoma, gastric cancers

UVA researchers discover Y chromosome gene linked to heart failure in men

UVA researchers discover Y chromosome gene linked to heart failure in men

Clinical trial to test the feasibility of using at-home cancer immunotherapy

Clinical trial to test the feasibility of using at-home cancer immunotherapy

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