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Changing antibiotic delivery method improves sepsis outcomes globally

Changing the way antibiotics are given to adult patients with sepsis will save thousands of lives a year globally, according to research by The University of Queensland and The George Institute for Global Health.

12 Jun 2024

Prolonged depression in young adults linked to cognitive decline in middle age

People who experience prolonged depressive symptoms starting in young adulthood may have worse thinking and memory skills in middle age, according to a study published in the June 12, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

12 Jun 2024

Analysis reveals the global burden of type 1 diabetes in adults aged 65 years and older

The number of people aged 65 and older with type 1 diabetes increased from 1.3 million in 1990 to 3.7 million in 2019, while death rates fell 25% from 4.7 per 100,000 population in 1990 to 3.5 in 2019, finds an analysis of data from over 200 countries and regions in The BMJ today.

12 Jun 2024

Low-birth-weight deliveries linked to cognitive decline in later life

People who give birth to infants less than 5.5 pounds may be more likely to have memory and thinking problems later in life than people who give birth to infants who do not have a low birth weight, according to a study published in the June 12, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

12 Jun 2024

Gastric bypass maintains weight loss and diabetes remission over 15 years, study shows

Roux-en-Y gastric bypass, a type of weight-loss surgery, kept type 2 diabetes in remission for up to 15 years and most of the weight off for up to 20 years in one of the largest long-term studies of patients undergoing the procedure.

12 Jun 2024

Synthetic cell mimics immune response via symmetry breaking

In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists at Johns Hopkins Medicine say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a governing principle of biology called "symmetry breaking."

12 Jun 2024

Mechanistic connections between vascular health and dementia risk in older adults

A new review paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 10, entitled, "Peripheral vascular dysfunction and the aging brain."

12 Jun 2024

Long-read RNA sequencing reveals novel insights into alternative splicing and disease genetics

Tokyo Medical and Dental University (TMDU) researchers harness long-read RNA sequencing to decode genetic intricacies and disease links.

12 Jun 2024

UC San Diego engineers develop algae-based microrobots for lung cancer treatment

Engineers at the University of California San Diego have developed microscopic robots, known as microrobots, capable of swimming through the lungs to deliver cancer-fighting medication directly to metastatic tumors.

12 Jun 2024

HiDEF-seq technique reveals the origins of DNA mutations in single strands

Mutations are changes in the molecular "letters" that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including cancer.

12 Jun 2024

Nutrients deficiency pattern possible important risk factor for mortality in older adults with hypertension

Researchers determine the impact of nutrient deficiencies on mortality risk in older adults with hypertension.

12 Jun 2024

Study identifies genetic predictors of X chromosome loss in aging women

Researchers have identified inherited genetic variants that may predict the loss of one copy of a woman's two X chromosomes as she ages, a phenomenon known as mosaic loss of chromosome X, or mLOX.

12 Jun 2024

Climate change-related environmental stressors associated with increased CVD mortality

Cardiovascular disease (CVD) is the leading cause of death worldwide, accounting for approximately one in every three deaths, with more than 20 million deaths reported in 2021 according to a 2024 World Heart Federation report.

12 Jun 2024

Enhancing CAR-T cell therapy with biodegradable scaffolds

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway.

12 Jun 2024

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Treating prostate cancer with immunotherapy is currently difficult to do. But results from a first in-human phase 1 trial using a chimeric antigen receptor (CAR) T cell therapy developed by researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States, showed that patients with advanced prostate cancer can be treated safely with the cellular immunotherapy with promising therapeutic activity, according to the phase 1 trial study published today in Nature Medicine.

12 Jun 2024

Inflammation in mid-life as a predictor of mobility decline in older age

In a recent study published in the Journal of the American Geriatric Society, having high inflammation in mid-life was associated with a clinically meaningful slower gait speed-;an indicator of mobility-;20 years later.

12 Jun 2024

Chronic kidney disease may be linked with tooth loss in postmenopausal women

Kidneys play a critical role in overall health by removing waste products from the blood. When they fail to sufficiently filter out foreign elements, several serious, lifethreatening, medical conditions can result.

12 Jun 2024

Differing definitions of iron deficiency lead to divergent estimates of prevalence, study finds

How different ways of defining iron deficiency (ID) impact the prevalence estimates of this common disorder among women.

12 Jun 2024

AI revolutionizes malaria diagnosis with 97.57% accuracy using EfficientNet

AI tool that uses deep learning to examine red blood cell images in blood smears for the timely detection of malaria.

12 Jun 2024

UD researchers pioneer universal, economical method for proteomics sample preparation

Proteins are workhorses that carry out most of the biological functions in our cells. While the genes we inherit from our parents, our so-called genome, are fixed and usually remain unchanged throughout our lives, proteins in our bodies are constantly changing, as we age, under different health conditions and upon stimulation, such as with medical treatment.

11 Jun 2024

Blood News and Research

Changing antibiotic delivery method improves sepsis outcomes globally

Prolonged depression in young adults linked to cognitive decline in middle age

Analysis reveals the global burden of type 1 diabetes in adults aged 65 years and older

Low-birth-weight deliveries linked to cognitive decline in later life

Gastric bypass maintains weight loss and diabetes remission over 15 years, study shows

Synthetic cell mimics immune response via symmetry breaking

Mechanistic connections between vascular health and dementia risk in older adults

Long-read RNA sequencing reveals novel insights into alternative splicing and disease genetics

UC San Diego engineers develop algae-based microrobots for lung cancer treatment

HiDEF-seq technique reveals the origins of DNA mutations in single strands

Nutrients deficiency pattern possible important risk factor for mortality in older adults with hypertension

Study identifies genetic predictors of X chromosome loss in aging women

Climate change-related environmental stressors associated with increased CVD mortality

Enhancing CAR-T cell therapy with biodegradable scaffolds

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Inflammation in mid-life as a predictor of mobility decline in older age

Chronic kidney disease may be linked with tooth loss in postmenopausal women

Differing definitions of iron deficiency lead to divergent estimates of prevalence, study finds

AI revolutionizes malaria diagnosis with 97.57% accuracy using EfficientNet

UD researchers pioneer universal, economical method for proteomics sample preparation

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