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New antibiotic lolamicin shows promise in fighting drug-resistant infections

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut.

29 May 2024

New research highlights a promising approach to tackling for ALS

A recent collaborative research endeavor, published in the prestigious Cell Press journal Cell Reports Medicine, highlights a promising therapeutic avenue for amyotrophic lateral sclerosis (ALS).

29 May 2024

RNA-based therapy shows promise in reducing cholesterol and triglycerides

A small interfering RNA (siRNA) investigational therapy that inhibits a gene involved in lipoprotein metabolism has been shown in a clinical trial led by Mount Sinai researchers to significantly reduce levels of different types of cholesterol and triglycerides in individuals with mixed hyperlipidemia, a condition in which fats build up in the blood.

29 May 2024

Researchers overturn the prevailing theory for colorectal tumor initiation

Research led by Weill Cornell Medicine provides new evidence that most colorectal cancers begin with the loss of intestinal stem cells, even before cancer-causing genetic alterations appear.

29 May 2024

Study finds kidney complications following heart failure hospitalization

In a study of Medicare beneficiaries, researchers from Brigham and Women's Hospital found that one year after hospitalization for heart failure, 6 percent of patients had progressed to dialysis.

29 May 2024

Heart healthy behaviors may slow biological aging, research shows

The benefit of better heart health may be associated with the positive impact of heart healthy lifestyle factors on biological aging (the age of the body and its cells), according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

29 May 2024

Study offers insight into early developmental risk factors for ADHD

Several early developmental factors are associated with an increased risk of ADHD during childhood and adolescence.

29 May 2024

GLP-1 receptor agonists effective for weight loss in obesity without diabetes

The benefit-harm balance of initiating Glucagon-like Peptide-1 (GLP-1) receptor agonists (RAs) versus a placebo intervention.

29 May 2024

RNAConnect, Inc. formally launches to drive RNA analysis

RNAConnect, a pioneering life science reagent company, officially launches today, promising groundbreaking solutions for exploring the real-world diversity of RNA sequence and structure.

From RNA Connect 29 May 2024

Decline in family physicians’ outpatient Medicare procedures amid aging demographic trends

Family physicians perform a wide range of procedures outside the hospital and tend to be office based. Examples may include surgical procedures such as excisions, suturing, and joint injections.

28 May 2024

Targeting CD47 to improve osimertinib efficacy in EGFR mutant NSCLC

NSCLC is the leading cause of cancer deaths globally, with EGFR mutations being a common feature in these cancers.

28 May 2024

New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

A recent study in Nature Medicine found that LM11A-31, targeting the p75 neurotrophin receptor, is safe and shows promise in slowing Alzheimer's disease progression. The trial indicated significant biomarker improvements and potential benefits for further clinical investigation.

28 May 2024

Reducing cancer treatment frequency could cut greenhouse gas emissions

Changing how often a popular cancer therapy is delivered would reduce greenhouse gas emissions and improve environmental impact without decreasing cancer survival, according to a new analysis from researchers at the University of Michigan Health Rogel Cancer Center.

28 May 2024

Study highlights a dietary strategy for health improvement and weight management

A new study by researchers from Arizona State University and their colleagues highlights a dietary strategy for significant health improvement and weight management.

28 May 2024

The prediabetes paradox: Balancing early intervention and overdiagnosis

Prediabetes, a diagnosis intended to identify high-risk persons and prevent progression to diabetes, has been a topic of ongoing debate, and experts continue to disagree about its screening criteria, interpretation, and implications.

28 May 2024

Assessing the effects of COVID-19 on breast cancer screening rates

Breast cancer is the second most common cancer among women in the U.S. Early detection of the disease through screening can greatly improve the chances of successful treatment and is an essential preventive service in primary care.

28 May 2024

Understanding organizational factors in medical assistant staffing ratios

Medical assistants (MAs) are among the fastest growing occupations within the U.S. primary care workforce, and many practices have expanded the roles and caregiving responsibilities of primary care MAs.

28 May 2024

Semaglutide shows significant kidney benefits in non-diabetic obese patients with heart disease

A recent study in Nature Medicine shows semaglutide reduces kidney risks in non-diabetic obese patients with cardiovascular disease by 22%. The SELECT trial results highlight semaglutide's benefits for kidney function and overall cardiovascular health.

28 May 2024

MUSC researchers unravel the mystery of cancer recurrence

MUSC Hollings Cancer Center researchers have unlocked a discovery that could help to explain why cancer can recur in patients who have undergone chemotherapy or radiotherapy.

28 May 2024

Exercise pattern study reveals lower Parkinson's risk for weekend warriors and regulars alike

A recent study in npj Digital Medicine found that both "weekend warrior" and regular exercise patterns significantly reduce Parkinson's disease (PD) risk. The findings suggest exercise duration is more critical than frequency in mitigating PD risk.

28 May 2024