Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Understanding Crohn's disease through 'mini-gut' models

Cambridge scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an important role in the disease and how it presents in patients.

10 Jun 2024

Itgb1 gene found to be crucial in preventing spongy heart disease

Having explored how the heart is formed in utero, a University of Houston pharmacology researcher is reporting how cells and molecules act during that early formation and what might cause the heart disease called left ventricular non-compaction.

10 Jun 2024

Genome sequencing identifies genetic disorders missed by exome analysis

Genetic mutations in human DNA can prevent proteins that perform important functions in the body from being formed correctly.

10 Jun 2024

Innovative FAP-targeted radioligand therapy controls disease progression in sarcoma

Fibroblast activation protein (FAP)-targeted radioligand therapy is safe and effective for treating patients with progressive metastatic tumors, specifically advanced sarcomas, according to research presented at the 2024 Society of Nuclear Medicine and Molecular Imaging Annual Meeting.

10 Jun 2024

Johns Hopkins researchers discover how epilepsy drug modulates brain activity

By super cooling a molecule on the surface of brain cells down to about minus 180 degrees Celsius -; nearly twice as cold as the coldest places in Antarctica -; scientists at Johns Hopkins Medicine say they have determined how a widely-used epilepsy drug works to dampen the excitability of brain cells and help to control, although not cure, seizures.

10 Jun 2024

CSHL team identifies crucial protein interactions in RNA splicing process

Bodybuilders and cellular mechanisms agree generating protein is a heavy lift. To complete the task, cells rely on complexes called spliceosomes.

10 Jun 2024

Glowing marker dye gives medics a 'second pair of eyes' during prostate cancer surgery

A glowing marker dye that sticks to prostate cancer cells could help surgeons to remove them in real-time, according to a study funded by Cancer Research UK.

10 Jun 2024

How Epstein-Barr virus shapes immune responses in multiple sclerosis

Study found that EBV-specific immune responses in MS patients showed higher IgG titers and cell-mediated reactions to EBV antigens compared to healthy controls, suggesting a complex role of EBV in MS development.

9 Jun 2024

New therapeutic target discovered for treatment-resistant melanoma

An international research team led by scientists from the University of Liège (Belgium) has discovered an interesting new therapeutic target for the treatment of melanoma resistant to targeted therapies.

8 Jun 2024

Unlocking the potential of ubiquitin-proteasome system in cancer treatment

A new editorial paper was published in Oncoscience (Volume 11) on May 6, 2024, entitled, "Restoring our ubiquitination machinery to overcome resistance in cancer therapy."

7 Jun 2024

Dundee scientists unlock key mechanism in Parkinson's disease defense

Scientists at the University of Dundee have uncovered the inner relay of a molecular switch that protects the brain against the development of Parkinson's disease.

7 Jun 2024

Critical role of protein-lipid interactions in mitochondrial energy production revealed

By studying mutations in yeast and human cells, Johns Hopkins Medicine scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.

7 Jun 2024

How increased mTOR activity shortens lifespan and promotes aging-related diseases

The reality of a population who is aging at an accelerated rate makes it a priority to understand what happens in the body over time, on a molecular scale.

7 Jun 2024

Simple peptide modification could unlock a whole class of targets for drug discovery

A relatively simple peptide modification could unlock a whole class of targets for drug discovery, new research shows.

7 Jun 2024

Key protein orco crucial for ant olfactory neuron survival and social behavior

While smell plays a considerable role in the social interactions of humans-;for instance, signaling fear or generating closeness-;for ants, it is vitally important.

7 Jun 2024

Understanding cancer progression through noninvasive two-color "diffuse in vivo flow cytometry"

In the relentless fight against cancer, a new technology promises to shed light on how we track and understand the spread of this disease within the body.

7 Jun 2024

Curcumin-based inhibition of thiol isomerases: A potential treatment for food allergies

Clinton Mathias, associate professor of nutritional sciences in the College of Agriculture, Health and Natural Resources (CAHNR), has discovered a potential new treatment for allergic reactions.

7 Jun 2024

Innovative therapeutic strategies for combating type 2 diabetes

One of the most confusing aspects for patients with type 2 diabetes mellitus is that they have high fasting glucose levels.

7 Jun 2024

Novel therapeutic approach shows promise for frontotemporal dementia in pre-clinical trials

Pre-clinical trials: A new therapeutic approach for the severe condition uses modified viruses to replace a missing protein in the brain.

7 Jun 2024

Mechanisms of aversive learning: How negative experiences shape neural circuits

'I'm not gonna do this again', we often say when faced with negative feedback, adverse effects, or disappointing outcomes. Thus, we attempt to learn from such negative experiences.

7 Jun 2024

Protein News and Research

Further Reading

Understanding Crohn's disease through 'mini-gut' models

Itgb1 gene found to be crucial in preventing spongy heart disease

Genome sequencing identifies genetic disorders missed by exome analysis

Innovative FAP-targeted radioligand therapy controls disease progression in sarcoma

Johns Hopkins researchers discover how epilepsy drug modulates brain activity

CSHL team identifies crucial protein interactions in RNA splicing process

Glowing marker dye gives medics a 'second pair of eyes' during prostate cancer surgery

How Epstein-Barr virus shapes immune responses in multiple sclerosis

New therapeutic target discovered for treatment-resistant melanoma

Unlocking the potential of ubiquitin-proteasome system in cancer treatment

Dundee scientists unlock key mechanism in Parkinson's disease defense

Critical role of protein-lipid interactions in mitochondrial energy production revealed

How increased mTOR activity shortens lifespan and promotes aging-related diseases

Simple peptide modification could unlock a whole class of targets for drug discovery

Key protein orco crucial for ant olfactory neuron survival and social behavior

Understanding cancer progression through noninvasive two-color "diffuse in vivo flow cytometry"

Curcumin-based inhibition of thiol isomerases: A potential treatment for food allergies

Innovative therapeutic strategies for combating type 2 diabetes

Novel therapeutic approach shows promise for frontotemporal dementia in pre-clinical trials

Mechanisms of aversive learning: How negative experiences shape neural circuits

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