DNA Methylation News and Research

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DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the most well characterized epigenetic mechanism.

Kidney transplantation turns back the clock on renal aging

This recent study in the Journal of Internal Medicine reveals that kidney transplantation mitigates the effects of renal aging in chronic kidney disease patients, outperforming dialysis. The research utilized DNA methylation clocks to assess biological age, finding that age acceleration decreased one year post-transplant but remained unchanged with dialysis.

17 Oct 2023

AI-based method shows promise for precision medicine

Artificial intelligence, AI, which finds patterns in complex biological data could eventually contribute to the development of individually tailored healthcare.

12 Oct 2023

New AI model can identify neuroanatomical regions vulnerable to age-related changes

The aging brain undergoes structural and cellular changes that can impact function and increase susceptibility to neurodegenerative disorders like Alzheimer's disease.

11 Oct 2023

New blood test could detect ovarian cancer early, improve treatment

High-grade serous ovarian carcinoma (HGSOC) is the most common type of ovarian cancer. It is also the most lethal form, in part because clinicians do not have effective ways to screen women for it during the cancer's early stages, when it's easiest to treat.

10 Oct 2023

Does renting accelerate biological aging? New study sparks housing policy debate

Living in privately rented homes is linked to faster biological aging, with its impact nearly double that of unemployment. However, these effects are reversible, highlighting the potential of housing policies in health improvement.

10 Oct 2023

Coffee, fiber, and the Mediterranean diet are key players in fighting nonalcoholic fatty liver disease

Dietary patterns, foods, and nutrients to ameliorate nonalcoholic fatty liver disease (NAFLD).

19 Sep 2023

Can your baby's gut bacteria predict food allergies?

Researchers in Italy delve into how changes in gut microbiota during the first 1000 days of life can influence the onset of food allergies in children. The study sheds light on various factors such as birth methods, breastfeeding, and antibiotic use that impact gut health, highlighting the need for more research on effective interventions for allergy prevention.

18 Sep 2023

Can yoga alleviate rheumatoid arthritis severity?

A recent Scientific Reports study investigated the effect of yoga on rheumatoid arthritis (RA) severity.

13 Sep 2023

Is DNA methylation the missing link in diagnosing and treating psoriasis and psoriatic arthritis?

Researchers across Europe have delved into the DNA methylation patterns in CD4+ T-cells of psoriasis and psoriatic arthritis (PsA) patients, unveiling potential new biomarkers for these conditions. Their study suggests that these unique profiles could serve as both diagnostic and prognostic tools, although further validation is needed for real-world clinical application.

10 Sep 2023

Promising new cervical cancer test fills in the gap missed by Pap tests

Researchers assessed a novel human papillomavirus (HPV) and host deoxyribonucleic acid (DNA) methylation score for adenocarcinoma in-situ (AIS) and cervical adenocarcinoma (ADC) screening.

8 Sep 2023

Novel test could improve detection of cervical adenocarcinoma

In findings with potentially important implications for cervical cancer screening, scientists at the National Cancer Institute (NCI)-designated Montefiore Einstein Cancer Center (MECC) have developed a test for detecting a type of cervical cancer that Pap tests often miss.

7 Sep 2023

‘Like a Russian roulette’: US military firefighters grapple with unknowns of PFAS exposure

A U.S. military firefighter for 32 years, Kurt Rhodes trained and performed his duties with aqueous film forming foam, or AFFF — a highly effective fire suppressant that he never knew contained PFAS chemicals, now known to be harmful to human health.

7 Sep 2023

Aligning Rhythms, Defying Alzheimer's: Intermittent Fasting's Role in Combating Alzheimer's Disease Neurodegeneration

News Medical interviewed Dr Paula Desplats, an Associate Professor of Neurosciences at the University of California San Diego.

1 Sep 2023

Novel non-invasive model may help predict preeclampsia before symptoms

Researchers developed a novel clinical diagnostic screening test to identify pregnancies at risk of developing preeclampsia.

31 Aug 2023

Study reveals biological mechanism behind the impact of fathers' early teenage smoking on offspring

A new study suggests boys who smoke in their early teens risk damaging the genes of their future children, increasing their chances of developing asthma, obesity and low lung function.

30 Aug 2023

Maternal obesity linked to childhood weight issues through DNA changes

Boston Birth Cohort study finds that maternal pre-pregnancy obesity alters newborn DNA methylation, potentially increasing the risk of obesity in the child. The research targets high-risk U.S. demographics and could guide future interventions for childhood obesity.

27 Aug 2023

DNA Methylation News and Research

Further Reading

Kidney transplantation turns back the clock on renal aging

AI-based method shows promise for precision medicine

New AI model can identify neuroanatomical regions vulnerable to age-related changes

New blood test could detect ovarian cancer early, improve treatment

Does renting accelerate biological aging? New study sparks housing policy debate

Coffee, fiber, and the Mediterranean diet are key players in fighting nonalcoholic fatty liver disease

Can your baby's gut bacteria predict food allergies?

Can yoga alleviate rheumatoid arthritis severity?

Is DNA methylation the missing link in diagnosing and treating psoriasis and psoriatic arthritis?

Promising new cervical cancer test fills in the gap missed by Pap tests

Novel test could improve detection of cervical adenocarcinoma

‘Like a Russian roulette’: US military firefighters grapple with unknowns of PFAS exposure

Aligning Rhythms, Defying Alzheimer's: Intermittent Fasting's Role in Combating Alzheimer's Disease Neurodegeneration

Novel non-invasive model may help predict preeclampsia before symptoms

Study reveals biological mechanism behind the impact of fathers' early teenage smoking on offspring

Maternal obesity linked to childhood weight issues through DNA changes

Scientists find way to 'press self-destruct button' in gastric cancer associated with Epstein-Barr Virus

The relationship between breast milk feeding and infants’ neurodevelopment via epigenetics

The interplay between the microbiota, the epigenome, and nutrition among obese adults during behavioral weight reduction

Gut microbiome may play a role in DNA methylation during weight loss

DNA Methylation eBook

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Changing the landscape of R&D to build clinical success from the ground up

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