Brain Cell News and Research

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Existing cancer drug shows promise in blocking alpha-synuclein spread in Parkinson's mice

In studies with genetically engineered mice, Johns Hopkins Medicine researchers say they have identified a potentially new biological target involving Aplp1, a cell surface protein that drives the spread of Parkinson's disease-causing alpha-synuclein.

18 Jun 2024

Revolutionary platform unveils detailed human brain architecture at multiple scales

A new platform enables simultaneous capture of protein expression, cellular morphology, neural projection, and synapse distribution in large-scale human brain tissues at multiple scales, researchers report.

13 Jun 2024

Johns Hopkins researchers discover how epilepsy drug modulates brain activity

By super cooling a molecule on the surface of brain cells down to about minus 180 degrees Celsius -; nearly twice as cold as the coldest places in Antarctica -; scientists at Johns Hopkins Medicine say they have determined how a widely-used epilepsy drug works to dampen the excitability of brain cells and help to control, although not cure, seizures.

10 Jun 2024

Study reveals mechanism behind brain's response to oxygen deprivation and memory loss

When we learn something new, our brain cells (neurons) communicate with each other through electrical and chemical signals.

7 Jun 2024

Curcumin nanoparticles show promise in treating neurodegenerative diseases

Review demonstrates curcumin's neuroprotective effects in neurodegenerative diseases, enhancing its potential through innovative nanoparticle formulations. This advancement could significantly improve treatments for diseases like Parkinson's, Alzheimer's, and Multiple Sclerosis.

6 Jun 2024

Injectable fish oil emulsion reduces brain damage in newborn rodents

An injectable emulsion containing two omega-3 fatty acids found in fish oil markedly reduced brain damage in newborn rodents after a disruption in the flow of oxygen to the brain near birth, a study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

6 Jun 2024

New computational method developed for linking DNA marks to gene activity

Scientists at La Jolla Institute for Immunology (LJI) have developed a new computational method for linking molecular marks on our DNA to gene activity.

4 Jun 2024

Researchers identify novel way to potentially slow down or halt Alzheimer’s progression

Researchers at the Icahn School of Medicine at Mount Sinai have made a significant breakthrough in Alzheimer's disease research by identifying a novel way to potentially slow down or even halt disease progression.

27 May 2024

Researchers produce advanced multidimensional maps of gene regulation networks in the brain

A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders.

24 May 2024

New CRISPR screen method reveals cellular drivers of neurological disorders

The brain is often referred to as a "black box"-;one that's difficult to peer inside and determine what's happening at any given moment.

20 May 2024

UQ scientists reveal protective effects of exercise on the aging brain

University of Queensland research has found exercise can help prevent or slow cognitive decline during aging.

20 May 2024

Columbia neuroscientists identify brain circuits for color perception in fruit flies

Perceiving something – anything – in your surroundings is to become aware of what your senses are detecting. Today, Columbia University neuroscientists identify, for the first time, brain-cell circuitry in fruit flies that converts raw sensory signals into color perceptions that can guide behavior.

16 May 2024

New technique reveals brain cells age at different rates

Engineers at the University of California San Diego have discovered that some brain cells age more rapidly than others, and they are disproportionately abundant in individuals afflicted with Alzheimer's disease.

14 May 2024

High-fat diet accelerates aging-related memory loss in rats

Study found that a high-fat diet exacerbates age-related cognitive decline in rats, even when microglia cells are removed from the equation, suggesting other pathways may play a role.

5 May 2024

Rapamycin shows promise in slowing Alzheimer's disease progression linked to seizures

Protein imbalances that increase brain cell excitability may explain why individuals with Alzheimer's disease (AD) who also experience seizures demonstrate more rapid cognitive decline than those who do not experience seizures.

2 May 2024

DELiVR's virtual reality training speeds up cell detection in complex brain datasets

Efficient neuronal activity detection in brain imaging.

25 Apr 2024

How neural barcodes shape episodic memory in chickadees

Black-capped chickadees have extraordinary memories that can recall the locations of thousands of morsels of food to help them survive the winter.

29 Mar 2024

Study shows cellular, molecular overlaps in ALS and FTLD

On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies frontotemporal dementia, manifest in very different ways. In addition, they are known to primarily affect very different regions of the brain.

22 Mar 2024

Discovery could revolutionize stem cell-based brain repair therapy for Parkinson's disease

Neuroscientists at University of Galway have made an exciting discovery that could revolutionize stem cell-based brain repair therapy for Parkinson's disease.

19 Mar 2024

Study reveals novel brain recovery mechanism after traumatic brain injury

A team of Medical University of South Carolina researchers, led by Onder Albayram, Ph.D., reports in PNAS Nexus that they have discovered a novel protective response by which the brain naturally repairs itself after traumatic brain injury.

13 Mar 2024