Dopaminergic News and Research

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New algorithm enhances deep brain stimulation for Parkinson's by targeting specific symptoms

Researchers from Mass General Brigham identified therapeutic targets that may optimize symptom-specific treatment for Parkinson’s disease.

8 Jun 2024

Curcumin nanoparticles show promise in treating neurodegenerative diseases

Review demonstrates curcumin's neuroprotective effects in neurodegenerative diseases, enhancing its potential through innovative nanoparticle formulations. This advancement could significantly improve treatments for diseases like Parkinson's, Alzheimer's, and Multiple Sclerosis.

6 Jun 2024

Stanford study reveals link between adaptive myelination and drug addiction

Our brains, even in adulthood, continually adapt to what we do, strengthening or weakening neural pathways as we practice new skills or abandon old habits.

5 Jun 2024

Unveiling the epigenetic impact of prenatal amphetamine exposure using C. elegans models

Amphetamine is a psychostimulant that has been used to treat a variety of brain dysfunctions. However, it is a highly abused drug.

30 May 2024

Study demonstrates link between disrupted developmental dopamine signaling and ASD

Recent evidence suggests that dopamine plays a crucial role in neural development. In a novel study, investigators demonstrated the link between disrupted developmental dopamine signaling and autism spectrum disorder (ASD).

16 May 2024

Genetic link identified between inflammatory bowel disease and Parkinson's disease

The researchers found, as expected from prior studies that LRRK2 is associated with IBD-PD and discovered new associations as well.

15 May 2024

New brain connectivity maps offer insights into human consciousness

In a paper titled, "Multimodal MRI reveals brainstem connections that sustain wakefulness in human consciousness," published today in Science Translational Medicine, a group of researchers at Massachusetts General Hospital, a founding member of the Mass General Brigham healthcare system, and Boston Children's Hospital, created a connectivity map of a brain network that they propose is critical to human consciousness.

2 May 2024

U of T researchers develop new approach for controlling neuron generation in Parkinson's disease

Researchers at the University of Toronto have found a way to better control the preclinical generation of key neurons depleted in Parkinson's disease, pointing toward a new approach for a disease with no cure and few effective treatments.

30 Apr 2024

Phase 2 trial reveals Lixisenatide may reduce motor disability in Parkinson’s patients

A trial of lixisenatide to assess its effects in early Parkinson’s disease.

18 Apr 2024

Ketamine's rapid impact on depression linked to immune system pathways

Study reveals ketamine's potent anti-inflammatory effects on neurological disorders, showing promise for treating major depressive disorder through modulation of neuroimmune pathways.

15 Apr 2024

Can psychedelics improve sexual functioning and satisfaction?

The influence of psychedelics on sexual functioning.

15 Apr 2024

Sweet truths and bitter pills: How free sugars affect human health

The current evidence about the effect of free sugars on health outcomes in humans, including mood, cognition, cardiovascular disease, diabetes, and obesity.

3 Apr 2024

Discovery could revolutionize stem cell-based brain repair therapy for Parkinson's disease

Neuroscientists at University of Galway have made an exciting discovery that could revolutionize stem cell-based brain repair therapy for Parkinson's disease.

19 Mar 2024

Microfluidic chips advance neurodegenerative disease research

Researchers review the role of microfluidic chip models in understanding neurodegenerative diseases, offering insights into the disease mechanisms and potential for drug development through innovative lab-on-a-chip technologies.

14 Mar 2024

Study finds link between freezing of gait and sleep disorders in Parkinson's patients

Parkinson's disease patients who experience freezing of gait (a sudden inability to initiate or continue movement, often resulting in a fall) wake up several times during the night, feel sleepy during the day, and have REM sleep behavior disorder.

5 Mar 2024

Researchers find differences in how people with impulse control disorder process consequences

Parkinson's disease is a neurological disorder that affects movement and muscle control. One characteristic of the disease is the deficiency of dopamine, a neurotransmitter or brain chemical that plays a role in movement and can impact how people think and feel.

4 Mar 2024

Mapping the brain: How cell types and location influence Parkinson’s disease

A single-cell spatial transcriptome analysis on murine brain expression in age and disease using a Parkinson's disease.

27 Feb 2024

Deep learning shines a new light on Parkinson's detection through the eye

Study demonstrates the potential of deep learning algorithms to predict Parkinson's disease (PD) through retinal fundus imaging, offering a non-invasive, early diagnostic tool.

18 Feb 2024

Researchers introduce a pioneering approach to combat neurodegenerative diseases

Researchers led by Northwestern University and the University of Wisconsin-Madison have introduced a pioneering approach aimed at combating neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and Amyotrophic lateral sclerosis (ALS).

16 Feb 2024

Scientists discover key pathway linking brain's habit center and motor learning region

Researchers explored how the cerebellum directly affects dopamine release in the substantia nigra compacta (SNc).

29 Jan 2024