Immune Response News and Research

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How tight binding between immune cells dictates T cell cancer-fighting ability

Immunotherapy, treatments that reinvigorate immune cells' anti-cancer activity or reprogram T cells to target cancer, has shown promise in treating leukemias but has not yet been realized in solid tumors.

30 May 2024

Newly discovered lincRNA controls the development and function of regulatory T cells

The T cells in our blood fight against cancer, viruses and bacteria. Specific regulatory T cells are required to control faulty immune responses, and disruption in their function may lead to autoimmune diseases or cancer.

30 May 2024

hnRNPM's protective role in protein synthesis precision uncovered

Researchers at Baylor College of Medicine and collaborating institutions have discovered that a protein called hnRNPM helps protect the integrity of the process cells use to make proteins.

30 May 2024

Vaccination remains crucial for preventing avian influenza spread, says study

Vaccination remains the most effective strategy for avian influenza prevention and control in humans, despite varying vaccine efficacy across strains.

29 May 2024

Novel method creates antibody-peptide inhibitor conjugates with enhanced therapeutic efficacy

Tumor cells often hijack normal physiological processes to support their growth, exploiting proteins that are in charge of essential cell functions.

29 May 2024

Scientists design new way to "cloak" proteins for targeted therapeutic delivery

Cornell University scientists have designed a way to "cloak" proteins in a generalized technique that could lead to repurposing things like antibodies for biological research and therapeutic applications.

28 May 2024

Understanding the link between EBV-infected B cells and multiple sclerosis

The Wistar Institute's Paul M. Lieberman, Ph.D., and lab team led by senior staff scientist and first author, Samantha Soldan, Ph.D., have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis.

28 May 2024

New genetic discoveries offer hope for targeted lupus therapies

Lupus is a lifelong, often painful and occasionally lethal autoimmune disease. Few treatments exist today beyond powerful steroids to knock down a patient's immune system -; a therapy that has its own serious risks.

23 May 2024

New optogenetics approach may offer better muscle control with less fatigue

For people with paralysis or amputation, neuroprosthetic systems that artificially stimulate muscle contraction with electrical current can help them regain limb function.

23 May 2024

Review highlights the rapidly evolving landscape of hepatocellular carcinoma treatment

Hepatocellular carcinoma (HCC), a prevalent form of cancer, profoundly influences the progression and prognosis of the disease through immune response mechanisms.

22 May 2024

Biological similarities found between "chemo brain" and brain fog after COVID-19

Brain fog after COVID-19 is biologically similar to cognitive impairment caused by cancer chemotherapy, something doctors often refer to as "chemo brain."

22 May 2024

4 ways vaccine skeptics mislead you on measles and more

Measles is on the rise in the United States. So far this year, the number of cases is about 17 times what it was, on average, during the same period in each of the four years before, according to the Centers for Disease Control and Prevention.

22 May 2024

Novel therapy reprograms immune cells, shrinks prostate and bladder cancers in animal study

A novel therapy that reprograms immune cells to promote antitumor activity helped shrink hard-to-treat prostate and bladder cancers in mice, according to research from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy and Johns Hopkins Drug Discovery.

21 May 2024

Impact of CLK kinase inhibitors 1C8 and GPS167 on cancer cell proliferation and metastasis

A new research paper was published in Oncotarget's Volume 15 on May 16, 2024, entitled, "The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response."

20 May 2024

Gut bacteria Ruminococcus gnavus can enhance the effects of cancer immunotherapy

Roughly one in five cancer patients benefits from immunotherapy – a treatment that harnesses the immune system to fight cancer.

17 May 2024

Study reveals positive impact of repeat COVID-19 vaccinations

Health-care workers received the first doses of the COVID-19 vaccine in December 2020.

17 May 2024

Vaccine candidate spurs elusive type of broadly neutralizing HIV antibodies

An HIV vaccine candidate developed at the Duke Human Vaccine Institute triggered low levels of an elusive type of broadly neutralizing HIV antibodies among a small group of people enrolled in a 2019 clinical trial.

17 May 2024

Proteins in the blood could warn people of cancer more than seven years before it is diagnosed

Researchers from the UK investigated associations between 1,463 plasma proteins and 19 cancers, using observational and genetic approaches in participants of the UK Biobank.

17 May 2024

Study identifies key gluten peptide triggering leaky gut in celiac patients

Today is International Celiac Day. Celiac disease is a chronic autoimmune condition that occurs in around one per cent of the world's population.

17 May 2024

RPGRIP1L gene expression levels can be a potential prognostic marker for invasive breast cancer

A protein called retinitis pigmentosa GTPase regulator interacting protein 1-like (RPGRIP1L) performs various functions that are important for development and for health throughout life, and mutations in the RPGRIP1L gene have been linked to different diseases.

15 May 2024

Immune Response News and Research

How tight binding between immune cells dictates T cell cancer-fighting ability

Newly discovered lincRNA controls the development and function of regulatory T cells

hnRNPM's protective role in protein synthesis precision uncovered

Vaccination remains crucial for preventing avian influenza spread, says study

Novel method creates antibody-peptide inhibitor conjugates with enhanced therapeutic efficacy

Scientists design new way to "cloak" proteins for targeted therapeutic delivery

Understanding the link between EBV-infected B cells and multiple sclerosis

New genetic discoveries offer hope for targeted lupus therapies

New optogenetics approach may offer better muscle control with less fatigue

Review highlights the rapidly evolving landscape of hepatocellular carcinoma treatment

Biological similarities found between "chemo brain" and brain fog after COVID-19

4 ways vaccine skeptics mislead you on measles and more

Novel therapy reprograms immune cells, shrinks prostate and bladder cancers in animal study

Impact of CLK kinase inhibitors 1C8 and GPS167 on cancer cell proliferation and metastasis

Gut bacteria Ruminococcus gnavus can enhance the effects of cancer immunotherapy

Study reveals positive impact of repeat COVID-19 vaccinations

Vaccine candidate spurs elusive type of broadly neutralizing HIV antibodies

Proteins in the blood could warn people of cancer more than seven years before it is diagnosed

Study identifies key gluten peptide triggering leaky gut in celiac patients

RPGRIP1L gene expression levels can be a potential prognostic marker for invasive breast cancer

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