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New armored CAR T cell therapy boosts response in Relapsed non-Hodgkin lymphoma patients

While CAR T cell therapy has revolutionized treatment for many blood cancers, including non-Hodgkin lymphoma (NHL), many patients who receive CAR T cell therapy do not experience a long-term remission.

13 Jun 2024

Targeting basophils to revitalize cytotoxic T-cells in tumor microenvironment

The ecosystem that surrounds a tumor, also known as the tumor microenvironment, includes immune cells, tissues, blood vessels and other cells that interact with each other and with the tumor.

13 Jun 2024

New research sheds light on IL-23's role in chronic inflammatory bowel diseases

Scientists at Weill Cornell Medicine discovered a previously unknown link between two key pathways that regulate the immune system in mammals-;a finding that impacts our understanding of chronic inflammatory bowel diseases (IBD).

12 Jun 2024

Enhancing CAR-T cell therapy with biodegradable scaffolds

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway.

12 Jun 2024

How Epstein-Barr virus shapes immune responses in multiple sclerosis

Study found that EBV-specific immune responses in MS patients showed higher IgG titers and cell-mediated reactions to EBV antigens compared to healthy controls, suggesting a complex role of EBV in MS development.

9 Jun 2024

Microneedle patch holds promise for promoting hair regrowth caused by alopecia areata

Alopecia areata (AA) is an autoimmune disease characterized by hair loss, which occurs when T cells of the immune system mistakenly attack hair follicles.

8 Jun 2024

Genetic discovery reveals key to inflammatory diseases

Researchers discovered that a specific haplotype on chromosome 21 is linked to five inflammatory diseases, offering insights into potential new treatments.

7 Jun 2024

Curcumin nanoparticles show promise in treating neurodegenerative diseases

Review demonstrates curcumin's neuroprotective effects in neurodegenerative diseases, enhancing its potential through innovative nanoparticle formulations. This advancement could significantly improve treatments for diseases like Parkinson's, Alzheimer's, and Multiple Sclerosis.

6 Jun 2024

Innovative microneedle patch shows promise in treating alopecia areata

Alopecia areata (AA) is an autoimmune disease characterized by hair loss, which occurs when T cells of the immune system mistakenly attack hair follicles.

6 Jun 2024

Cervix organ chips pave the way for next-generation studies on host-microbiome interactions

A group of researchers developed human Cervical Organ Chips to model the cervical interface.

4 Jun 2024

Young bone marrow transplants show promise in reversing Alzheimer's symptoms in mice

Researchers found that young bone marrow transplants rejuvenate aging immune cells, reducing Alzheimer's symptoms in mice models, suggesting a potential therapeutic approach for the disease.

4 Jun 2024

IgG from long COVID patients induces specific symptoms in mice, confirming autoimmunity's role

Researchers found that IgG from long COVID patients induces specific symptoms in mice, suggesting IgG's role in long COVID pathogenesis.

3 Jun 2024

Low-dose aspirin can reduce inflammatory responses to sleep restriction

A new study to be presented at the SLEEP 2024 annual meeting found that low-dose acetylsalicylic acid, also known as aspirin, can reduce inflammatory responses to sleep restriction.

3 Jun 2024

Statins found to prevent chronic inflammation-related cancers by inhibiting interleukin-33

The effects of statins via inhibition of interleukin 33 (IL-33).

3 Jun 2024

Intermittent fasting with protein pacing trumps calorie restriction in gut health and weight loss

A recent study in Nature Communications found that intermittent fasting with protein pacing (IF-P) is more effective than continuous calorie restriction (CR) in improving gut microbiota and metabolomic profiles, leading to greater weight and fat loss.

2 Jun 2024

Single infusion of engineered T-cells achieves lasting asthma remission in mice

Researchers demostrate that durable asthma remission can be achieved with engineered and long-lived CAR T-cell treatment in mice.

31 May 2024

Mast cells and PGE2: Key players in controlling asthma inflammation

Previous research indicates that mast cells, a type of immune cell found in the tissues throughout the body, cause inflammation during an asthma attack, inducing symptoms such as trouble breathing and narrowing of the airways.

30 May 2024

Newly discovered lincRNA controls the development and function of regulatory T cells

The T cells in our blood fight against cancer, viruses and bacteria. Specific regulatory T cells are required to control faulty immune responses, and disruption in their function may lead to autoimmune diseases or cancer.

30 May 2024

Statins may block an inflammation pathway involved in the development of cancer

A new study led by investigators from Mass General Cancer Center, a founding member of the Mass General Brigham healthcare system, reveals that statins-;commonly used cholesterol-lowering drugs-;may block a particular pathway involved in the development of cancer that results from chronic inflammation.

30 May 2024

Exercise-induced exerkines: Secret weapon in disease prevention and therapy

A recent review in Signal Transduction and Targeted Therapy highlights the role of exercise-induced molecules, exerkines, in disease prevention and treatment, emphasizing their molecular mechanisms and therapeutic potential.

29 May 2024

Interleukin News and Research

New armored CAR T cell therapy boosts response in Relapsed non-Hodgkin lymphoma patients

Targeting basophils to revitalize cytotoxic T-cells in tumor microenvironment

New research sheds light on IL-23's role in chronic inflammatory bowel diseases

Enhancing CAR-T cell therapy with biodegradable scaffolds

How Epstein-Barr virus shapes immune responses in multiple sclerosis

Microneedle patch holds promise for promoting hair regrowth caused by alopecia areata

Genetic discovery reveals key to inflammatory diseases

Curcumin nanoparticles show promise in treating neurodegenerative diseases

Innovative microneedle patch shows promise in treating alopecia areata

Cervix organ chips pave the way for next-generation studies on host-microbiome interactions

Young bone marrow transplants show promise in reversing Alzheimer's symptoms in mice

IgG from long COVID patients induces specific symptoms in mice, confirming autoimmunity's role

Low-dose aspirin can reduce inflammatory responses to sleep restriction

Statins found to prevent chronic inflammation-related cancers by inhibiting interleukin-33

Intermittent fasting with protein pacing trumps calorie restriction in gut health and weight loss

Single infusion of engineered T-cells achieves lasting asthma remission in mice

Mast cells and PGE2: Key players in controlling asthma inflammation

Newly discovered lincRNA controls the development and function of regulatory T cells

Statins may block an inflammation pathway involved in the development of cancer

Exercise-induced exerkines: Secret weapon in disease prevention and therapy

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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