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Two new studies offer insights into the molecular biology of neuropsychiatric disease

Working under the umbrella of the PsychENCODE Consortium, the mental health research project established in 2015 by the National Institutes of Health, a team of Mount Sinai scientists has uncovered important new insights into the molecular biology of neuropsychiatric disease through two new studies published in a special issue of Science on Friday, May 24.

24 May 2024

Researchers produce advanced multidimensional maps of gene regulation networks in the brain

A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders.

24 May 2024

New small molecule offers hope in combating antibiotic resistance

Researchers from the University of Oxford have developed a new small molecule that can suppress the evolution of antibiotic resistance in bacteria and make resistant bacteria more susceptible to antibiotics.

24 May 2024

The case of the armadillo: Is it spreading leprosy in Florida?

In an open-air barn at the edge of the University of Florida, veterinarian Juan Campos Krauer examines a dead armadillo's footpads and ears for signs of infection.

24 May 2024

Comprehensive study provides new understandings of genomic influences on neuropsychiatric disease

A new analysis has revealed detailed information about genetic variation in brain cells that could open new avenues for the targeted treatment of diseases such as schizophrenia and Alzheimer's disease.

23 May 2024

Physician-pharmacy integration not associated with change in the care of cancer patients

Integration of pharmacies with physician practices, where on-site pharmacies open at physician practice locations, is a growing trend in cancer treatment.

23 May 2024

New stem cell transplant approach may expand donor pool for high-risk blood cancer patients

A new treatment approach using an older drug may enable more patients with high-risk blood cancers to receive transplanted stem cells from unrelated, partially matched donors, according to a study conducted by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and colleagues.

23 May 2024

UCLA research connects genetic risk and brain changes in autism

A groundbreaking study led by UCLA Health has unveiled the most detailed view of the complex biological mechanisms underlying autism, showing the first link between genetic risk of the disorder to observed cellular and genetic activity across different layers of the brain.

23 May 2024

Cherries and berries: Nature’s sweet remedy for a healthy heart

Research paper reviews the cardiovascular benefits of phenolic compounds in cherries and berries, highlighting their potential to reduce inflammation, oxidative stress, and improve lipid profiles. Regular consumption of these fruits can significantly lower the risk of cardiovascular diseases.

23 May 2024

Novel catalog of gene-isoform variation unveiled in the developing human brain

A team led by researchers at UCLA and the University of Pennsylvania has produced a first-of-its kind catalog of gene-isoform variation in the developing human brain.

23 May 2024

New genetic discoveries offer hope for targeted lupus therapies

Lupus is a lifelong, often painful and occasionally lethal autoimmune disease. Few treatments exist today beyond powerful steroids to knock down a patient's immune system -; a therapy that has its own serious risks.

23 May 2024

Harnessing molecular pathways governed by key gene to enhance wheat yields

A study from the University of Adelaide has discovered molecular pathways regulated by a gene traditionally used to control wheat-flowering behavior could be altered to achieve greater yields.

23 May 2024

New chemical modification improves effectiveness and safety of ASO therapy for CNS diseases

Diseases that affect the brain and spinal cord can be particularly devastating, and finding new and more effective ways to treat these conditions is an important goal for researchers and clinicians alike.

23 May 2024

Study explores how different modes of cell division evolved in close relatives of fungi and animals

Cell division is one of the most fundamental processes of life. From bacteria to blue whales, every living being on Earth relies on cell division for growth, reproduction, and species survival.

23 May 2024

Clues from bird flu’s ground zero on dairy farms in the Texas Panhandle

In early February, dairy farmers in the Texas Panhandle began to notice sick cattle. The buzz soon reached Darren Turley, executive director of the Texas Association of Dairymen: "They said there is something moving from herd to herd."

23 May 2024

New study advocates for de-escalating breast cancer surgery in women aged 55 and older

Surgery involving sentinel lymph node biopsy for middle-aged women with estrogen receptor-positive (ER+) breast cancer may do more harm than good, according to a new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers.

22 May 2024

LMU study identifies dual genetic pathways increasing cardiovascular disease risk

LMU researchers have discovered two independent ways by which genetic variants increase the risk of cardiovascular diseases.

22 May 2024

Ancient viral sequences in the human genome may contribute to psychiatric disorder susceptibility

New research led by King's College London has found that thousands of DNA sequences originating from ancient viral infections are expressed in the brain, with some contributing to susceptibility for psychiatric disorders such as schizophrenia, bipolar disorder, and depression.

22 May 2024

100-year-old BCG vaccine protects individuals with type 1 diabetes from infectious diseases

In new research, investigators at Massachusetts General Hospital (MGH) show that the 100-year-old Bacillus Calmette-Guérin (BCG) vaccine, originally developed to prevent tuberculosis, protects individuals with type 1 diabetes from severe COVID-19 disease and other infectious diseases.

22 May 2024

Single-cell analysis reveals insights into immune responses during xenotransplantation

Surgical teams at NYU Langone Health performed the world's first genetically modified pig kidney transplants into a human body in September and November 2021, and then transplanted two pig hearts in the summer of 2022.

22 May 2024

Genetic News and Research

Two new studies offer insights into the molecular biology of neuropsychiatric disease

Researchers produce advanced multidimensional maps of gene regulation networks in the brain

New small molecule offers hope in combating antibiotic resistance

The case of the armadillo: Is it spreading leprosy in Florida?

Comprehensive study provides new understandings of genomic influences on neuropsychiatric disease

Physician-pharmacy integration not associated with change in the care of cancer patients

New stem cell transplant approach may expand donor pool for high-risk blood cancer patients

UCLA research connects genetic risk and brain changes in autism

Cherries and berries: Nature’s sweet remedy for a healthy heart

Novel catalog of gene-isoform variation unveiled in the developing human brain

New genetic discoveries offer hope for targeted lupus therapies

Harnessing molecular pathways governed by key gene to enhance wheat yields

New chemical modification improves effectiveness and safety of ASO therapy for CNS diseases

Study explores how different modes of cell division evolved in close relatives of fungi and animals

Clues from bird flu’s ground zero on dairy farms in the Texas Panhandle

New study advocates for de-escalating breast cancer surgery in women aged 55 and older

LMU study identifies dual genetic pathways increasing cardiovascular disease risk

Ancient viral sequences in the human genome may contribute to psychiatric disorder susceptibility

100-year-old BCG vaccine protects individuals with type 1 diabetes from infectious diseases

Single-cell analysis reveals insights into immune responses during xenotransplantation

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