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A second-generation targetted antibody for potential cancer therapy

The overproduction, or 'overexpression', of the epidermal growth factor receptor (EGFR) is one of the most common aberrations in cancer, and subsequently agents that inhibit EGFR are among the most hotly-pursued potential products in the pharmaceutical industry.

6 May 2004

Genetic flaw that may put some people at far greater risk of heart attacks

One of the significant players in this event is the molecule cytokine lymphotoxin-alpha (LTA), which helps to regulate inflammation, a result of the emergency call upon the body's immune system.

6 May 2004

Organic superglues, disease treatments and better food flavourings

Organic superglues, disease treatments and better food flavourings: these are some of the projects where synthetic organic chemist Carol Taylor employs her skills.

5 May 2004

New insight into the function of RNA helicases

If DNA can be compared to an architect who gets all the glory for designing the building, RNA can be compared to the engineer who often goes unrecognized, but is needed to turn the blueprints into a real three-dimensional, functional and safe structure.

5 May 2004

Discovery of molecular switch could lead to new treatments for lymphoma and other forms of cancer

Turning a vital component of cancer cells from bodyguard to assassin could form the basis of new cancer treatments, according to a report published this week.

4 May 2004

Chemical thumbprint can help determine if tumor is returning or dying

Brain tumor survivors live with the constant worry that their cancer might come back. And even if they have a brain scan every few months to check, doctors often can't tell the difference between new cancer growth and tissue changes related to their treatment with radiation or chemotherapy.

3 May 2004

Males and females respond differently to brain injury

Researchers at Children’s Hospital of Pittsburgh have found that males and females respond differently to brain injury and therefore, boys with brain injuries may require different life-saving treatments than girls.

1 May 2004

First imaging-based diagnostic test for living Alzheimer’s

Mayo Clinic researchers have devised a way to produce enhanced MRI (magnetic resonance imaging) pictures of the destructive brain lesions that cause Alzheimer’s disease. This advance using laboratory mice lays the foundation for the first imaging-based diagnostic test for living Alzheimer’s disease patients.

30 Apr 2004

Researchers find mucus plays key role in cancer

Investigators at the Dana-Farber/Harvard Cancer Center in Boston became intrigued with the thick, slimy stuff when they learned that breast, lung, colon, and other tumor cells make more than 50 times more of a certain type of it than normal cells.

29 Apr 2004

Scientists have unraveled the behavior of one key component of bacteria

The researchers studied a mechanism of action they call the "magic spot" – an important regulator of gene expression. They describe their results in the current issue of the journal Cell.

29 Apr 2004

Mystery surrounding ageing, death and cancer is dispelled by new study

Scientists from Cancer Research UK and Breast Cancer Campaign have uncovered the first evidence of an entirely new system for holding the ravages of time at bay.

29 Apr 2004

A burst of brain energy depends more on a unique molecular cycle than on blood flow variation

A century old mystery is taking place in your head as you read these words. Blood vessels in regions of your brain are widening, bathing cells in an increased blood flow.

28 Apr 2004

The world's smallest computer made entirely of biological molecules

The world's smallest computer (around a trillion can fit in a drop of water) might one day go on record again as the tiniest medical kit.

28 Apr 2004

Northern Ireland scientists target bowel cancer treatment

Cancer Research N. Ireland scientists are developing a way for doctors to predict which treatment will be most successful in individual bowel cancer patients.

28 Apr 2004

Sprouts and broccoli may reduce risk of high blood pressure

Glucoraphanin, also known as sulforaphane glucosinolate (SGS(TM)), a naturally-occurring compound found in broccoli sprouts and broccoli, may reduce risk of high blood pressure, cardiovascular disease and stroke, according to new research published in the May 4 issue of the Proceedings of the National Academy of Sciences of the USA.

28 Apr 2004

AGT Biosciences Limited and ChemGenex Therapeutics today announced merger agreement

AGT Biosciences Limited of Melbourne, Australia and privately held ChemGenex Therapeutics, Inc. of Menlo Park, California, today announced that they have signed a merger agreement. The cross-border merger creates a new, genomics-driven pharmaceutical company with leading edge capabilities for drug discovery and development, as well as two drug candidates in Phase II human trials for cancer.

28 Apr 2004

Improvement of Parkinson’s disease symptoms when neurorestorative molecule pumped to the center of the brain

A recent study has shown clinical improvement of Parkinson’s disease symptoms after long-term infusion of a neurorestorative molecule, pumped directly to the center of the brain. The study will be presented at the American Academy of Neurology 56th Annual Meeting in San Francisco, Calif., April 24 – May 1, 2004.

27 Apr 2004

UK scientists have discovered cancer cells life and death scenario following anti-cancer treatment

CANCER Research UK scientists have discovered how some cancer cells choose to live and others die following anti-cancer treatment, unveiling their findings in the prestigious journal PNAS today.

26 Apr 2004

Scientists studying the adhesive properties of the neural cell adhesion molecule have found that two opposing models of cell adhesion are both correct

Scientists studying the adhesive properties of the neural cell adhesion molecule (NCAM) -- a protein that helps bind the nervous system together -- have found that two opposing models of cell adhesion are both correct.

26 Apr 2004