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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Innovative blood test boosts accuracy of lung cancer screening

A blood-based, cell-free deoxyribonucleic acid (cfDNA) fragmentome assay for lung cancer detection.

11 Jun 2024

Study unlocks the secrets of mammalian longevity through DNA methylation analysis

Researchers developed DNA methylation-based models predicting maximum lifespan, gestation, and sexual maturity across 348 mammalian species, revealing key epigenetic markers of longevity.

10 Jun 2024

Understanding Crohn's disease through 'mini-gut' models

Cambridge scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an important role in the disease and how it presents in patients.

10 Jun 2024

Precision-guided treatment boosts outcomes in children with high-risk cancers

Study reveals that precision-guided treatment (PGT) improves outcomes in high-risk pediatric cancer patients, but clinical adoption remains low due to physician uncertainty and lack of long-term survival data.

10 Jun 2024

Efficient whole-gene insertions can be achieved with improved gene-editing technology

Scientists at the Broad Institute of MIT and Harvard have improved a gene-editing technology that is now capable of inserting or substituting entire genes in the genome in human cells efficiently enough to be potentially useful for therapeutic applications.

10 Jun 2024

New study reveals gut microbiome's critical role in aging and heart disease

Researchers in China discovered that gut microbiome diversity, influenced by metabolic health and age, significantly impacts cardiovascular disease risk.

9 Jun 2024

Surprising link between a diverse oral microbiome and better cognitive function in aging

Study found that higher oral microbiome diversity is linked to better cognitive function and fewer memory issues in older US adults, highlighting the "oral-brain axis."

9 Jun 2024

Do taste genes influence how much alcohol we drink and our body fat?

Study examines how polymorphisms in bitter taste receptor genes relate to alcohol consumption and body fat percentage, revealing significant associations with TAS2R13 but not TAS2R38.

9 Jun 2024

Molecular Devices opens custom-built site in Cardiff for manufacturing of patient-derived organoids

Today, Molecular Devices, LLC., a leading high-performance life science solutions provider, officially opened its custom-built site in Cardiff, UK.

8 Jun 2024

Study sheds light on the rate and nature of mutations in mitochondrial DNA

A new study from deCODE genetics uses pedigrees and sequence data from 64,806 Icelanders to shed light on the rate and nature of mutations in mitochondrial DNA (mtDNA) and the peculiar dynamics of its maternal transmission.

7 Jun 2024

Gene therapy trial: restored hearing in children with hereditary deafness

The safety and effectiveness of binaural adeno-associated virus 1 (AAV1)-human otoferlin (hOTOF) therapy in five children with autosomal recessive deafness 9 (DFNB9).

7 Jun 2024

MGI Tech unveils new european headquarters in Berlin, Germany

MGI (MGI Tech Co., Ltd. or its subsidiaries, together referred to MGI), a company committed to building core tools and technologies that drive innovation in life science, today announced the opening of its new European headquarters in Berlin, Germany to support the life science community across the region.

From MGI 7 Jun 2024

Genetic discovery reveals key to inflammatory diseases

Researchers discovered that a specific haplotype on chromosome 21 is linked to five inflammatory diseases, offering insights into potential new treatments.

7 Jun 2024

Exploring the biology behind maternal mental health disorders

Pregnancy and new motherhood transform a woman's body as well as her life. While this is often a joyous time, it can sometime lead to mental health disorders, most often anxiety and depression.

6 Jun 2024

Early detection and intervention as key strategies to combat colorectal cancer

Colorectal Cancer (CRC) is set to transform from a severe disease to a controllable condition through early detection and intervention.

6 Jun 2024

AI-powered liquid biopsy shows promise in early detection of lung cancer

Using artificial intelligence technology to identify patterns of DNA fragments associated with lung cancer, researchers from the Johns Hopkins Kimmel Cancer Center and other institutions have developed and validated a liquid biopsy that may help identify lung cancer earlier.

6 Jun 2024

Researchers identify a potential metabolic target for cancer immunotherapy

Researchers at the VIB-KU Leuven Center for Cancer Biology have identified a potential target for cancer immunotherapy.

6 Jun 2024

Developing pre-symptomatic diagnostic tools for Alzheimer's disease using long-read RNA sequencing

Researchers at the University of Kentucky Sanders-Brown Center on Aging are working to develop a pre-symptomatic disease diagnostic tool for Alzheimer's disease.

6 Jun 2024

Short course of immunotherapy prior to surgery effective in treating a subset of colon cancer patients

A short course of immunotherapy was found to be highly effective in a subset of patients with colon cancer.

5 Jun 2024

Synergistic cytotoxicity in pancreatic cancer: HDAC, PARP inhibitors, and decitabine show promise

A new research paper was published in Oncotarget's Volume 15 on June 3, 2024, entitled, "Synergistic cytotoxicity of histone deacetylase and poly-ADP ribose polymerase inhibitors and decitabine in pancreatic cancer cells: Implications for novel therapy."

5 Jun 2024