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Repurposing human-approved drugs for prion disease treatment

Prions are the abnormal, pathogenic agents that are transmissible and are able to induce abnormal folding of specific normal cellular proteins.

16 May 2024

Sensing a Healthier Future with Sustainable Nanomaterials and Biosensors

In this interview conducted at Pittcon 2024 in San Diego, we spoke to this year's Keynote Speaker Professor Omowunmi (Wunmi) Sadik about how sustainable nanomaterials are transforming human health.

From Pittcon 16 May 2024

Clinical trial suggests hypertension self-management strategies may be effective to control blood pressure

The study findings suggest that self-management strategies for hypertension may effectively reduce blood pressure levels over 24 months without increasing healthcare resource utilization or adverse events as compared to usual care.

16 May 2024

Anti-obesity medications slash heart disease risk in obese patients, study finds

A study in the journal Obesity evaluated the impact of new anti-obesity medications (AOMs) on cardiovascular disease (CVD) among obese individuals, finding that these medications reduce the risk of CVD complications, particularly heart failure and atrial fibrillation.

15 May 2024

New study finds Sfrp1 as a potential therapeutic target in cancer treatment

Cancer is a leading cause of death globally. One of the primary reasons why cancer is such a deadly disease is the ability of cancer cells to become drug-resistant.

15 May 2024

Menthol-derived molecules: promising candidates for anti-inflammatory and anti-obesity therapy

Modified derivatives of natural products have led to significant therapeutic advances and commercial success in recent times.

15 May 2024

Unraveling the link between HLA genes and drug eruptions

Although medications can often help patients find a cure or respite from their condition, millions of people worldwide suffer from unpredictable drug toxicities every year.

15 May 2024

Blood proteins predict cancer risk seven years in advance, studies find

Two Cancer Research UK-funded studies from Oxford Population Health have discovered proteins in the blood that could warn people of cancer more than seven years before it is diagnosed.

15 May 2024

3D printing technique enables the fabrication of customized pharmaceutical tablets

A new technique for 3D printing medication has enabled the printing of multiple drugs in a single tablet, paving the way for personalized pills that can deliver timed doses.

15 May 2024

Study uncovers unique platelet population linked to aging and blood clotting diseases

As people age, they become more prone to blood clotting diseases, when blood cells called platelets clump together when they don't need to and can cause major issues such as strokes and cardiovascular disease.

15 May 2024

Investigating age-associated gene expression changes in mouse sweat glands

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "Characterization of age-associated gene expression changes in mouse sweat glands."

15 May 2024

Lactate is essential to buffering the effects of a carbohydrate meal, study shows

As a student competing in track and field at his Parlier high school, Robert Leija was obsessed with how to improve his performance and, in particular, prevent the buildup of lactic acid in his muscles during training.

15 May 2024

Tribal nations invest opioid settlement funds in traditional healing to treat addiction

Outside the Mi'kmaq Nation's health department sits a dome-shaped tent, built by hand from saplings and covered in black canvas.

15 May 2024

Genetic link identified between inflammatory bowel disease and Parkinson's disease

The researchers found, as expected from prior studies that LRRK2 is associated with IBD-PD and discovered new associations as well.

15 May 2024

More than 20,000 volunteers join effort to accelerate dementia drug development

More than 20,000 volunteers have been recruited to a resource aimed at speeding up the development of much-needed dementia drugs. The cohort will enable scientists in universities and industry to involve healthy individuals in clinical trials to test whether new drugs can slow the decline in various brain functions including memory and delay the onset of dementia.

15 May 2024

St. Jude researchers unveil mechanisms to block PXR and enhance drug potency

Deaths from cancer or infections can occur when available treatments are ineffective. Once turned on, pregnane X receptor (PXR) activates the expression of genes encoding enzymes that metabolize external chemicals, including drugs.

14 May 2024

Innovative 'mini-brains' could revolutionize Alzheimer's diagnosis and treatment

Using an innovative new method, a University of Saskatchewan (USask) researcher is building tiny pseudo-organs from stem cells to help diagnose and treat Alzheimer's.

14 May 2024

Pharmacological treatment reduces specific crimes in adolescents with ADHD

A study in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP), published by Elsevier, found that pharmacological treatment of attention-deficit/hyperactivity disorder (ADHD) reduced violence- and public-order related crimes.

14 May 2024

Human cell-based model of thoracic aortic aneurysm offers new opportunities for drug development

Using human cells in laboratory rats, Michigan Medicine researchers have developed a functional model of thoracic aortic aneurysm, creating opportunities for more effective understanding of disease development and treatments for the potentially fatal condition, a study suggests.

14 May 2024

Racial and ethnic disparities in Alzheimer's diagnosis and CNS drug prescription

Compared to Black and Asian people, white and Hispanic people with Alzheimer's disease and related dementias were most likely to be diagnosed with symptoms like depression and agitation, according to a new study from the USC Schaeffer Center for Health Policy & Economics.

14 May 2024

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Drugs News and Research

Repurposing human-approved drugs for prion disease treatment

Sensing a Healthier Future with Sustainable Nanomaterials and Biosensors

Clinical trial suggests hypertension self-management strategies may be effective to control blood pressure

Anti-obesity medications slash heart disease risk in obese patients, study finds

New study finds Sfrp1 as a potential therapeutic target in cancer treatment

Menthol-derived molecules: promising candidates for anti-inflammatory and anti-obesity therapy

Unraveling the link between HLA genes and drug eruptions

Blood proteins predict cancer risk seven years in advance, studies find

3D printing technique enables the fabrication of customized pharmaceutical tablets

Study uncovers unique platelet population linked to aging and blood clotting diseases

Investigating age-associated gene expression changes in mouse sweat glands

Lactate is essential to buffering the effects of a carbohydrate meal, study shows

Tribal nations invest opioid settlement funds in traditional healing to treat addiction

Genetic link identified between inflammatory bowel disease and Parkinson's disease

More than 20,000 volunteers join effort to accelerate dementia drug development

St. Jude researchers unveil mechanisms to block PXR and enhance drug potency

Innovative 'mini-brains' could revolutionize Alzheimer's diagnosis and treatment

Pharmacological treatment reduces specific crimes in adolescents with ADHD

Human cell-based model of thoracic aortic aneurysm offers new opportunities for drug development

Racial and ethnic disparities in Alzheimer's diagnosis and CNS drug prescription

Drug Discovery - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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