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Novel small molecule oral antiviral could be a game-changer in the fight against future pandemics

Obeldesivir (GS-5245), a novel investigational small molecule oral antiviral, represents a new tool in the ongoing effort to prepare for future pandemics.

4 Jun 2024

Alcohol plus cabin pressure at higher altitude may threaten sleeping plane passengers' heart health

The combination of alcohol plus cabin pressure at cruising altitude may threaten sleeping plane passengers' heart health, particularly on long haul flights, suggests the first study of its kind, published online in the respiratory journal Thorax.

4 Jun 2024

SU2C-SARC032 trial: Immunotherapy reduces relapse risk in soft tissue sarcoma by 43%

For the last three decades, breakthroughs have been sparse for soft tissue sarcomas, which are rare cancers that affect muscles, fat and other connective tissues.

4 Jun 2024

Low-dose aspirin can reduce inflammatory responses to sleep restriction

A new study to be presented at the SLEEP 2024 annual meeting found that low-dose acetylsalicylic acid, also known as aspirin, can reduce inflammatory responses to sleep restriction.

3 Jun 2024

Novel male contraceptive gel suppresses sperm production faster than similar birth control methods

A novel male contraceptive gel combining two hormones, segesterone acetate (named Nestorone) and testosterone, suppresses sperm production faster than similar experimental hormone-based methods for male birth control, according to a new study.

3 Jun 2024

Thyroid eye disease patients experience lasting improvements after treatment with teprotumumab

Most patients with thyroid eye disease treated with teprotumumab didn't require additional treatments nearly 2 years later, according to industry-supported research being presented Sunday at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass., and published in the journal Thyroid.

3 Jun 2024

Breakthrough male contraceptive gel shows rapid results in clinical trial

Male contraceptive gel combines hormones for faster sperm production suppression.

3 Jun 2024

Experimental treatment for metastatic pancreatic cancer shows promise in phase 2 clinical trial

Clinicians at Georgetown University's Lombardi Comprehensive Cancer Center reported promising preliminary findings based on outcomes in the first six patients with metastatic pancreatic cancer enrolled in a phase 2 clinical trial of the experimental drug BXCL701 in combination with the immunotherapy drug pembrolizumab (Keytruda).

3 Jun 2024

Progesterone therapy shows mixed results for neurodevelopment in infants with heart defects

A randomized clinical trial published in JAMA Network Open found no significant overall benefit of maternal progesterone therapy on neurodevelopmental outcomes in infants with congenital heart defects, but observed improvements in female children and specific heart conditions.

2 Jun 2024

Precision medicine doubles progression-free survival in young cancer patients

Cancer is the leading cause of disease-related death in children in most developed countries, and at least a quarter of these patients are diagnosed with aggressive high-risk or relapsed cancers, with an expected five-year survival rate of less than 30%.

31 May 2024

Stress and pain linked to worse outcomes in HER2-positive breast cancer patients

Secondary analyses of a phase 3 clinical trial have revealed that breast cancer patients who reported high levels of pain and stress were more likely than their study peers to experience worse invasive disease-free survival (iDFS) and worse overall survival (OS).

31 May 2024

Breakthrough CAR T therapy and shorter targeted therapy durations offer hope for patients with leukemia

The novel anti-CD19 autologous chimeric antigen receptor (CAR) T cell therapy obecabtagene autoleucel (obe-cel) achieved durable remissions in 40% of patients with relapsed or refractory B-ALL without a subsequent stem cell transplant (SCT), according to results from the Phase Ib/II FELIX clinical trial presented today by Elias Jabbour, M.D., professor of Leukemia.

31 May 2024

Eye-tracking technology offers earlier, more accurate autism diagnosis

Nearly 3% of all children in the United States are diagnosed with autism, according to the Centers for Disease Control and Prevention.

31 May 2024

Radiomics imaging analysis can effectively forecast hearing status of vestibular schwannoma patients

A recent study demonstrates that radiomics imaging analysis can effectively forecast the hearing status of patients with vestibular schwannoma patients.

31 May 2024

New mobile app shows dramatic success in smoking cessation

A new mobile application, developed under the leadership of researchers from the University of Oulu, Finland, has proven to be an effective aid for long-term smokers attempting to quit.

31 May 2024

Wake Forest researchers to study bone health post-bariatric surgery with $1.5 million NIH grant

Researchers at Wake Forest University of School of Medicine have received a five-year, $1.5 million grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the National Institutes of Health, to study bone microarchitecture in patients following bariatric surgery.

30 May 2024

Clinical Trial News and Research

Novel small molecule oral antiviral could be a game-changer in the fight against future pandemics

Alcohol plus cabin pressure at higher altitude may threaten sleeping plane passengers' heart health

SU2C-SARC032 trial: Immunotherapy reduces relapse risk in soft tissue sarcoma by 43%

Low-dose aspirin can reduce inflammatory responses to sleep restriction

Novel male contraceptive gel suppresses sperm production faster than similar birth control methods

Thyroid eye disease patients experience lasting improvements after treatment with teprotumumab

Breakthrough male contraceptive gel shows rapid results in clinical trial

Experimental treatment for metastatic pancreatic cancer shows promise in phase 2 clinical trial

Progesterone therapy shows mixed results for neurodevelopment in infants with heart defects

Precision medicine doubles progression-free survival in young cancer patients

Stress and pain linked to worse outcomes in HER2-positive breast cancer patients

Breakthrough CAR T therapy and shorter targeted therapy durations offer hope for patients with leukemia

Eye-tracking technology offers earlier, more accurate autism diagnosis

Radiomics imaging analysis can effectively forecast hearing status of vestibular schwannoma patients

New mobile app shows dramatic success in smoking cessation

Wake Forest researchers to study bone health post-bariatric surgery with $1.5 million NIH grant

Study examines the cost-effectiveness of a targeted immunotherapy for lung cancer

Snap, track, eat: Taking photos of food could be key to better diets

BRCA1 testing during prenatal care could prevent cancer, save lives

Early peanut consumption slashes allergy risk by 71%, landmark study finds

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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