Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

UCSF scientists discover less invasive prenatal treatment for Angelman syndrome

In a discovery that opens the door to a less invasive way of treating some serious disorders before birth, UC San Francisco scientists have found that delivering medicine through amniotic fluid is as effective as delivering it to the fetal brain via cerebrospinal fluid.

4 Mar 2024

Penn engineers develop targeted lung delivery system using lipid nanoparticles

Penn Engineers have developed a new means of targeting the lungs with lipid nanoparticles (LNPs), the miniscule capsules used by the Moderna and Pfizer-BioNTech COVID-19 vaccines to deliver mRNA, opening the door to novel treatments for pulmonary diseases like cystic fibrosis.

1 Mar 2024

FB1006: AI-discovered drug advances to clinical trials for ALS treatment

Amyotrophic Lateral Sclerosis (ALS) is a fatal type of motor neuron disease characterized by progressive degeneration of nerve cells in the spinal cord and brain, resulting in muscle weakness and paralysis that can include the inability to walk and speak, or even swallow and breathe.

27 Feb 2024

Breakthrough discovery offers hope for reducing infections in cystic fibrosis patients

University of Queensland researchers have identified an opportunity to reduce infections in people living with cystic fibrosis.

22 Feb 2024

Cedars-Sinai researchers discover why some injured kidneys heal while others develop scarring

Cedars-Sinai investigators have discovered why some injured kidneys heal while others develop scarring that can lead to kidney failure.

22 Feb 2024

Targeting the Hippo signaling pathway to treat systemic sclerosis

Systemic sclerosis causes the skin to tighten and harden resulting in a potentially fatal autoimmune condition that is associated with lung fibrosis and kidney disease.

21 Feb 2024

Mitochondrial activation enhances cardiac regeneration therapy

Regenerative therapy to treat heart failure is more effective when the mitochondria of the regenerative cells are activated prior to treatment.

21 Feb 2024

Breakthrough gene therapy method utilizes bird retrotransposon for safe gene insertion

The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease.

20 Feb 2024

Innovative computer model of the lung enables detailed simulation of radiation effects

An innovative computer model of a human lung is helping scientists simulate, for the first time, how a burst of radiation interacts with the organ on a cell-by-cell level.

20 Feb 2024

New standards for evaluating aging biomarkers unveiled

A new paper led by Harvard researchers has zeroed in on biomarkers of aging using omic data from population-based studies.

16 Feb 2024

Risk of non-alcoholic fatty liver disease for cardiovascular disease and all cause death in patients with type 2 diabetes mellitus

Researchers investigated the link between non-alcoholic fatty liver disease in individuals with type 2 diabetes mellitus (T2DM) and all-cause death and cardiovascular disease.

16 Feb 2024

Study may open up new ways of approaching metabolic diseases

A study led by the University of Barcelona and the Biomedical Research Networking Center in Diabetes and Associated Metabolic Disorders (CIBERDEM) reveals how a new mechanism could improve the efficiency of currently available treatments for diabetes.

12 Feb 2024

Blood biomarkers in TGF-β pathway identify hidden liver cancer risk

A new research paper was published in Genes & Cancer on February 5, 2023, entitled, "Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in patients with cirrhosis."

9 Feb 2024

Immune cells in overdrive: Study finds unbalanced response worsens lung infections

CD4+ T cells have been highlighted in the scientific literature for the important role they play in the immune response to lung infections.

8 Feb 2024

Patients with non-alcoholic fatty liver disease may benefit from increased dietary niacin intake

Whether higher dietary niacin intake lowers the risk of all-cause, heart and cerebrovascular disease(s).

6 Feb 2024

UVA scientists develop new approach to machine learning for identifying heart drug

University of Virginia scientists have developed a new approach to machine learning – a form of artificial intelligence – to identify drugs that help minimize harmful scarring after a heart attack or other injuries.

5 Feb 2024

CAR T cells target senescent cells, improve healthspan in mice

Chimeric antigen receptor (CAR) T cells have transformed the treatment of blood cancers in recent years. And there have been positive signs the "living drugs" can be harnessed against other diseases, like autoimmune disorders.

2 Feb 2024

Scientists coax a deadly bacterium to destroy itself from the inside out

Northwestern University researchers have successfully coaxed a deadly pathogen to destroy itself from the inside out.

31 Jan 2024

Study: Up to 10% of dementia cases in veterans may be caused by liver disease

As many as 10% of older U.S. veterans diagnosed with dementia may suffer instead from reversible cognitive decline caused by advanced liver disease, according to an analysis from the Virginia Commonwealth University's School of Medicine and the Richmond VA Medical Center.

31 Jan 2024

Study reveals key mechanism behind obesity-related metabolic dysfunction

Researchers found that feeding a high-fat diet (HFD) causes mitochondrial dysfunction and fragmentation in white adipocytes in mice.

31 Jan 2024

Fibrosis News and Research

Further Reading

UCSF scientists discover less invasive prenatal treatment for Angelman syndrome

Penn engineers develop targeted lung delivery system using lipid nanoparticles

FB1006: AI-discovered drug advances to clinical trials for ALS treatment

Breakthrough discovery offers hope for reducing infections in cystic fibrosis patients

Cedars-Sinai researchers discover why some injured kidneys heal while others develop scarring

Targeting the Hippo signaling pathway to treat systemic sclerosis

Mitochondrial activation enhances cardiac regeneration therapy

Breakthrough gene therapy method utilizes bird retrotransposon for safe gene insertion

Innovative computer model of the lung enables detailed simulation of radiation effects

New standards for evaluating aging biomarkers unveiled

Risk of non-alcoholic fatty liver disease for cardiovascular disease and all cause death in patients with type 2 diabetes mellitus

Study may open up new ways of approaching metabolic diseases

Blood biomarkers in TGF-β pathway identify hidden liver cancer risk

Immune cells in overdrive: Study finds unbalanced response worsens lung infections

Patients with non-alcoholic fatty liver disease may benefit from increased dietary niacin intake

UVA scientists develop new approach to machine learning for identifying heart drug

CAR T cells target senescent cells, improve healthspan in mice

Scientists coax a deadly bacterium to destroy itself from the inside out

Study: Up to 10% of dementia cases in veterans may be caused by liver disease

Study reveals key mechanism behind obesity-related metabolic dysfunction

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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