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How COVID-19 targets the pancreas revealed

The study uncovers the role of the PLAC8 protein in making the human pancreas vulnerable to SARS-CoV-2 infection, leading to pancreatic injury and complications in severe COVID-19 cases. The findings open up new avenues for understanding how the virus affects multiple organ systems and offer a potential target for future treatments.

12 Sep 2023

Musashi-2 protein plays key role in the regulation of mass and metabolic processes in skeletal muscle

Researchers from Tokyo Metropolitan University have shown that the protein Musashi-2 (Msi2) plays a key role in the regulation of mass and metabolic processes in skeletal muscle.

11 Sep 2023

Researchers use machine learning to predict drug approval chances before clinical trials

Developing new drugs is paramount in discovering innovative treatments and preventing diseases. This is vital not only for advancing medicine but also for the overall health and well-being of humanity.

8 Sep 2023

Can brown fat really keep you slim? New study digs into the science of diet-induced thermogenesis

The research paper delves into the role of brown adipose tissue and its protein, UCP1, in diet-induced thermogenesis, questioning whether it could be a key to fighting obesity. Despite some evidence suggesting that brown fat activity could influence weight, the study calls for more research to determine the causality between reduced brown adipose tissue activity and obesity.

7 Sep 2023

RIT researchers use CRISPR to develop new treatment for degenerative disc disease

Rochester Institute of Technology researchers are improving non-invasive treatment options for degenerative disc disease, an ailment that impacts 3 million adults yearly in the U.S., according to the Mayo Clinic.

6 Sep 2023

New blood test pinpoints Parkinson's disease through mitochondrial DNA damage

Researchers have developed a new blood test that measures mitochondrial DNA damage as a potential marker for Parkinson's disease (PD). The study shows the test could aid in diagnosing PD and assessing responses to LRRK2 kinase inhibitors, which may help in reducing mitochondrial damage in PD patients.

4 Sep 2023

Review finds correlation between milk oligosaccharides and infant brain development

In a recent article published in Nutrients, researchers investigated the current evidence of the impact of milk oligosaccharides (MOS) on early life neurocognitive and brain development.

30 Aug 2023

Study identifies an endogenous bile acid that alleviates non-alcoholic fatty liver disease

A study finds that hyodeoxycholic acid alleviates non-alcoholic fatty liver disease by modulating the gut-liver axis.

22 Aug 2023

Platelets play a role in mediating the rejuvenating effects of exercise during physiological brain ageing

The impacts of physical activity on the neuronal formation and prevent age-related cognitive decay.

22 Aug 2023

Pig kidney xenotransplantation continues to function well after 32 days

Surgeons at NYU Langone Health have transplanted a genetically engineered pig kidney that continues to function well after 32 days in a man declared dead by neurologic criteria and maintained with a beating heart on ventilator support.

16 Aug 2023

Next-generation sequencing provides novel insights into the mechanisms underlying autism and myotonic muscular dystrophy

The pathomechanistic connection between autism and myotonic muscular dystrophy type 1.

16 Aug 2023

Newly discovered protein kinase shows promise for establishing future obesity and diabetes treatments

Researchers used genetically modified animal models to investigate the role of the newly discovered Traf2- and NCK-interacting protein kinase (TNIK) in obesity and metabolic dysfunction.

15 Aug 2023

Researchers uncover genetic machinery responsible for EBV-induced B cell growth transformation

B cells or B lymphocytes are an important part of the body's immune system. When healthy B cells are infected with the Epstein-Barr virus (EBV), they undergo growth transformation, a process that immortalizes B cells, leading to their uncontrolled proliferation.

7 Aug 2023

Researchers discover how aging can lead to chronic metabolic disorders

Korean researchers have unveiled a novel signaling pathway that fosters aging-related chronic metabolic disorders.

3 Aug 2023

TTUHSC researcher receives $1.76 million grant to investigate new pancreatic cancer treatment

With a survival rate in the single digits, pancreatic ductal adenocarcinoma (PDAC) is highly lethal. In fact, by the time PDAC is clinically diagnosed, it is already considered incurable via surgery or other means in up to 90% of patients.

2 Aug 2023

Cancer-causing gene also plays a crucial role in aging, study finds

A gene called Myc (pronounced "mick") that is among the most important drivers of cancer in both mice and humans also plays a newly discovered crucial role in aging, according to a new Cell Reports study by researchers at UPMC Children's Hospital of Pittsburgh and the University of Pittsburgh School of Medicine.

24 Jul 2023

Knockout News and Research

How COVID-19 targets the pancreas revealed

Musashi-2 protein plays key role in the regulation of mass and metabolic processes in skeletal muscle

Researchers use machine learning to predict drug approval chances before clinical trials

Can brown fat really keep you slim? New study digs into the science of diet-induced thermogenesis

RIT researchers use CRISPR to develop new treatment for degenerative disc disease

New blood test pinpoints Parkinson's disease through mitochondrial DNA damage

Review finds correlation between milk oligosaccharides and infant brain development

Study identifies an endogenous bile acid that alleviates non-alcoholic fatty liver disease

Platelets play a role in mediating the rejuvenating effects of exercise during physiological brain ageing

Pig kidney xenotransplantation continues to function well after 32 days

Next-generation sequencing provides novel insights into the mechanisms underlying autism and myotonic muscular dystrophy

Newly discovered protein kinase shows promise for establishing future obesity and diabetes treatments

Researchers uncover genetic machinery responsible for EBV-induced B cell growth transformation

Researchers discover how aging can lead to chronic metabolic disorders

TTUHSC researcher receives $1.76 million grant to investigate new pancreatic cancer treatment

Cancer-causing gene also plays a crucial role in aging, study finds

Study reveals potential target for repairing beta-cell dysfunction in Type 2 diabetes

Unveiling the key defender: PLSCR1 identified as a potent anti-SARS-CoV-2 factor in COVID-19 immunity

New mouse model mimics the development of frailty in older adults

How B-cells and androgens contribute to the development of PCOS

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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