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Analysis of diabetes drugs

Most oral medications prescribed for type 2 diabetes are similarly effective for reducing blood glucose, but the drug metformin is less likely to cause weight gain and may be more likely than other treatments to decrease so-called bad cholesterol, according to a report funded by HHS Agency for Healthcare Research and Quality.

17 Jul 2007

Current guidelines for blood glucose self-monitoring should be reviewed

A new study published on bmj.com questions the value of blood glucose monitoring among patients with well-controlled, non-insulin dependent (type 2) diabetes.

27 Jun 2007

Diabetes easily identified in pregnant women with simple blood test

More than a third of women who suffer from diabetes during pregnancy develop type 2 diabetes within five years and those most at risk can be predicted from their blood glucose levels at diagnosis, according to a study published in the June issue of the Postgraduate Medical Journal .

8 Jun 2007

Laparoscopic gastric banding surgery improves insulin resistance

A new study examining the overall and gender-related effects of laparoscopic gastric banding surgery (LGBS) on insulin resistance, body composition, and metabolic risk markers six months post-surgery has found significant improvements in insulin resistance.

2 May 2007

Novel anti-oxidant and anti-inflammatory agent reduces coronary events

Heart attacks are caused by a build-up and instability of plaque in the coronary arteries, which is often a result of chronic inflammation of the blood vessel walls.

31 Mar 2007

Pioglitazone may help slow progression of artery wall thickening

A medication given to diabetics to improve their body's sensitivity to insulin also appears to slow the thickening of their artery walls, according to a study posted online by JAMA: The Journal of the American Medical Association.

13 Nov 2006

Approval of integrated insulin pump and continuous glucose system a significant step towards artificial pancreas technology

The Juvenile Diabetes Research Foundation (JDRF) has said that the federal government's approval of an insulin pump that also provides real-time, continuous glucose monitoring is a significant step on the path to the development of an artificial pancreas, with the potential to significantly improve diabetes care and lower the risk of complications.

13 Apr 2006

MannKind initiates two phase 3 studies of inhaled Technosphere insulin

MannKind Corporation has announced that it has initiated patient enrollment in two pivotal 12-month Phase 3 clinical trials of Technosphere Insulin (TI) in patients with Type 1 and Type 2 Diabetes.

7 Mar 2006

Actos reduces the combined risk of non-fatal heart attacks, strokes in patients with type-2 diabetes

A study published in The Lancet shows that Takeda's Actos (pioglitazone HCl), an oral glucose lowering medication, significantly reduces the combined risk of non-fatal heart attacks, strokes and deaths by an additional 16% on top of standard medication

10 Oct 2005

Lowering blood sugar levels could reduce the risk of coronary heart disease

Lowering blood sugar levels could reduce the risk of coronary heart disease in both diabetics and non-diabetics, according to researchers at the Johns Hopkins Bloomberg School of Public Health and other institutions.

19 Sep 2005

Women's health suffers under welfare reform

Women who are current and former welfare recipients suffer a whole host of health problems - and getting a job doesn't always help matters.

29 Jun 2005

Insulin resistance drug with anti-inflammatory effects reduces risk factors

A drug, which reduces insulin resistance and also may have anti-inflammatory and other effects on blood vessels, lowered cardiovascular risk factors in patients with diabetes more than another diabetes medicine, even though both drugs improved blood sugar control equally, according to a new study (PDF) in the June 21, 2005, issue of the Journal of the American College of Cardiology.

21 Jun 2005

Chromium picolinate significantly reduces weight gain associated with common antidiabetic medication

...according to a study released today. Researchers at the Pennington Biomedical Research Center (PBRC), who conducted the study, also found that chromium significantly improved blood sugar control and insulin sensitivity.

16 Jun 2005

Tight glucose control lowers CVD by about 50 percent in diabetes

A significantly lower risk of heart disease can now be added to the list of proven long-term benefits of tight glucose control in people with type 1 diabetes.

12 Jun 2005

Rimonabant study shows significant improvements in HbA1c and cardiometabolic risk factors in people with type 2 diabetes

The reported results of a one-year phase III study in 1045 people with type 2 diabetes treated with rimonabant, the first in a new class of therapeutic agents called selective CB1 Blockers, were that rimonabant 20 mg significantly improved HbA1c (a measure of blood sugar control), dyslipidemia (abnormal levels of fat in the blood), and systolic blood pressure with a concomitant substantial reduction in abdominal obesity in people with type 2 diabetes treated with oral anti-diabetic medications and requiring further control.

12 Jun 2005

New study suggests Pioglitazone HCl may significantly improve key predictors of cardiovascular risk

Study results published in the May 17th issue of Circulation, the journal of the American Heart Association, found that the diabetes medication pioglitazone HCl reduced carotid artery intima-media thickness (IMT). Patients taking pioglitazone also experienced significant reductions in insulin resistance, C-reactive protein (a marker for inflammation) and blood pressure, all of which contribute to the overall risk for cardiovascular disease.

9 May 2005

New beta blocker may help diabetic patients with high blood pressure

A medication that is commonly used to control high blood pressure does not raise blood sugar levels in diabetics who also have high blood pressure, according to researchers from Rush University Medical Center.

9 Nov 2004

Link between elevated blood sugar levels in diabetics and increased risk of life-threatening forms of cardiovascular disease

A Johns Hopkins study suggests that people with type I and type II diabetes would be well advised to monitor their blood sugar levels more than the usual twice daily to make sure that levels are not elevated over 150 milligrams per deciliter for sustained periods.

20 Sep 2004

Exubera shows sustained blood glucose control in patients with type 2 diabetes

New data showed that Exubera (inhaled insulin) was effective and well tolerated in controlling blood glucose levels over a two-year period in patients with Type 2 diabetes.

8 Sep 2004

Summary of The Euro Heart Survey on the diabetic state of patients with coronary artery disease

The survey engaged 110 centres in 25 countries recruiting 4,196 patients referred to a cardiology department or outpatient clinic due to CAD. A total of 2 107 of these patients were admitted on acute basis while 2,854 had an elective consultation. Patient data were collected via a web-based case record form.

30 Aug 2004