Animal Model News and Research

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New optogenetics approach may offer better muscle control with less fatigue

For people with paralysis or amputation, neuroprosthetic systems that artificially stimulate muscle contraction with electrical current can help them regain limb function.

23 May 2024

Improved animal model captures full picture of periodontal disease progression

Periodontal disease, represented by periodontitis, is the leading cause of tooth loss and affects close to one in five adults worldwide.

22 May 2024

Understanding the role of oxidative stress in Alzheimer's disease pathogenesis

The number of people suffering from Alzheimer's disease (AD) is expected to reach 100 million by 2050, but there is still no effective therapy.

21 May 2024

World's first human mini-brain with a fully functional blood-brain barrier developed

In a pioneering achievement, a research team led by experts at Cincinnati Children's have developed the world's first human mini-brain that incorporates a fully functional blood-brain barrier (BBB).

20 May 2024

Non-viral gene therapy offers hope for chronic low back pain sufferers

A novel non-viral gene therapy for discogenic back pain (DBP).

20 May 2024

Study proposes a novel therapeutic avenue for tackling EHF-induced cholangiocarcinogenesis

This study is led by Dr. Yiming Luo (Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology) and Professor. Huifang Liang (Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology).

14 May 2024

Breakthrough research offers promise for developing new immune therapies for cancer

Scientists from Trinity College Dublin have made an important breakthrough that offers promise for developing new immune therapies for cancer.

9 May 2024

Rutgers scientists create CRISPR-edited mice to study the neurobiology of Tourette disorder

In research that may be a step forward toward finding personalized treatments for Tourette disorder, scientists at Rutgers University–New Brunswick have bred mice that exhibit some of the same behaviors and brain abnormalities seen in humans with the disorder.

6 May 2024

Durable lymph-node expansion improves vaccine responses against tumors

Each one of us has around 600 lymph nodes (LNs) – small, bean-shaped organs that house various types of blood cells and filter lymph fluid – scattered throughout our bodies.

6 May 2024

Modified sugar molecules boost stem cell therapy for brain repair after cardiac arrest

Researchers at the University of Maryland School of Medicine (UMSOM) have identified an innovation in stem cell therapy to regenerate neural cells in the brain after cardiac arrest in an animal model.

6 May 2024

Inulin fiber exacerbates inflammatory bowel disease, study finds

Inulin, a type of fiber found in certain plant-based foods and fiber supplements, causes inflammation in the gut and exacerbates inflammatory bowel disease in a preclinical model, according to a new study by Weill Cornell Medicine investigators.

2 May 2024

Glycoengineered stem cells enhance brain recovery after cardiac arrest, study finds

Researchers at the University of Maryland School of Medicine have identified an innovation in stem cell therapy to regenerate neural cells in the brain after cardiac arrest in an animal model.

2 May 2024

New Kaposi sarcoma mouse model could be key to drug development

Researchers at UNC Lineberger Comprehensive Cancer Center, after decades of research efforts, have developed a mouse model of Kaposi sarcoma that could be key to the development of new drugs to treat the disease.

29 Apr 2024

Study explores the effects of ovulation inducing method on embryo quality

Low birth rates have become a serious problem in many developed countries throughout the world, with Japan being a prime example. In Japan particularly, aging and stress have led to a massive rise in infertility, which now affects one in every 4.4 couples.

22 Apr 2024

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Study introduces Reverse Vaccine Development as a strategic approach to identify correlates of protection early in vaccine development against antimicrobial-resistant pathogens, aiming to mitigate risks such as significant phase-III clinical trial failures.

7 Apr 2024

New protein-based micromaterials developed for targeted cancer therapy

Researchers at the Universitat Autònoma de Barcelona (UAB), in collaboration with the Sant Pau Research Institute and the CIBER-BBN, have developed micromaterials made up only of proteins, capable of delivering over an extended period of time nanoparticles that attack specific cancer cells and destroy them.

5 Apr 2024

Scientists develop trivalent vaccine offering broad protection against coronaviruses

Scientists have been searching for the optimal coronavirus vaccine since the Covid-19 pandemic started.

1 Apr 2024

Study identifies brain energy metabolism dysfunction in neuropsychiatric disorders

A global collaborative research group comprising 131 researchers from 105 laboratories across seven countries announces a groundbreaking research paper submitted to eLife.

26 Mar 2024

UCLA researchers develop promising vaccine against deadly melioidosis bacterium

In a mouse study, UCLA researchers tested a vaccine against the bacterium that causes melioidosis and found it was highly protective against the disease, which is endemic in many tropical areas, causing approximately 165,000 cases with 89,000 fatalities around the world each year.

22 Mar 2024

Aging affects regulatory T cells' ability to promote myelin regeneration

Regulatory T lymphocytes are cells that are responsible for regulating the immune system and have regenerative functions in many contexts, including myelin restoration.

20 Mar 2024

Animal Model News and Research

New optogenetics approach may offer better muscle control with less fatigue

Improved animal model captures full picture of periodontal disease progression

Understanding the role of oxidative stress in Alzheimer's disease pathogenesis

World's first human mini-brain with a fully functional blood-brain barrier developed

Non-viral gene therapy offers hope for chronic low back pain sufferers

Study proposes a novel therapeutic avenue for tackling EHF-induced cholangiocarcinogenesis

Breakthrough research offers promise for developing new immune therapies for cancer

Rutgers scientists create CRISPR-edited mice to study the neurobiology of Tourette disorder

Durable lymph-node expansion improves vaccine responses against tumors

Modified sugar molecules boost stem cell therapy for brain repair after cardiac arrest

Inulin fiber exacerbates inflammatory bowel disease, study finds

Glycoengineered stem cells enhance brain recovery after cardiac arrest, study finds

New Kaposi sarcoma mouse model could be key to drug development

Study explores the effects of ovulation inducing method on embryo quality

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

New protein-based micromaterials developed for targeted cancer therapy

Scientists develop trivalent vaccine offering broad protection against coronaviruses

Study identifies brain energy metabolism dysfunction in neuropsychiatric disorders

UCLA researchers develop promising vaccine against deadly melioidosis bacterium

Aging affects regulatory T cells' ability to promote myelin regeneration

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Sensing a Healthier Future

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