Neutrophils News and Research

RSS

Targeting macrophages for enhanced vascular integrity and healing in ischemic injuries

Innate immune cells including macrophages and neutrophils have unique properties that allows them to quickly accumulate in large numbers at the site of infection or injury.

6 Jun 2024

Fertility warning: SARS-CoV-2 can linger in sperm for months after infection

Researchers at the University of São Paulo (USP) in Brazil have shown for the first time that SARS-CoV-2, the virus that causes COVID-19, can remain in the sperm of patients for up to 90 days after hospital discharge and up to 110 days after the initial infection, reducing semen quality.

4 Jun 2024

Young bone marrow transplants show promise in reversing Alzheimer's symptoms in mice

Researchers found that young bone marrow transplants rejuvenate aging immune cells, reducing Alzheimer's symptoms in mice models, suggesting a potential therapeutic approach for the disease.

4 Jun 2024

Exercise-induced exerkines: Secret weapon in disease prevention and therapy

A recent review in Signal Transduction and Targeted Therapy highlights the role of exercise-induced molecules, exerkines, in disease prevention and treatment, emphasizing their molecular mechanisms and therapeutic potential.

29 May 2024

Heart failure triggers multimorbidity by altering stem cells, study reveals

Researchers identified that heart failure (HF) promotes multimorbidity by altering hematopoietic stem cells (HSCs) to produce pro-inflammatory macrophages, increasing vulnerability in multiple organs. The study highlights the role of suppressed TGF-β signaling in these alterations, contributing to chronic inflammation and subsequent health issues.

28 May 2024

Study reveals ferroptosis as a major driver of severe COVID-19 lung damage

Ferroptosis, an iron-dependent cell death mechanism, is identified as a key factor in severe COVID-19 lung disease, suggesting potential new therapeutic targets.

22 May 2024

Unveiling the role of neutrophils in lung cancer progression

Lung cancer remains a leading global health concern, responsible for the highest number of cancer-related deaths worldwide.

16 May 2024

Durable lymph-node expansion improves vaccine responses against tumors

Each one of us has around 600 lymph nodes (LNs) – small, bean-shaped organs that house various types of blood cells and filter lymph fluid – scattered throughout our bodies.

6 May 2024

Ketone supplement boosts efficacy of prostate cancer immunotherapy

Adding a pre-ketone supplement -; a component of a high-fat, low-carb ketogenic diet -; to a type of cancer therapy in a laboratory setting was highly effective for treating prostate cancer, researchers from the University of Notre Dame found.

26 Apr 2024

Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

A review in Nature Reviews Nephrology presents the association between immune cells and the development of hypertension, suggesting potential new therapeutic targets to mitigate the disease by managing inflammation.

26 Apr 2024

Immune dysfunction mechanism discovered in stroke and heart attack patients

Every year, between 250,000 and 300,000 people in Germany suffer from a stroke or heart attack.

23 Apr 2024

Tumor microbiomes offer new insights for enhancing cancer therapies

Comprehensive review reveals the significant impact of tumor-resident bacteria on metastatic cancer, showing how microbiome genomes influence tumor biology, immune system response, and treatment effectiveness. It lays the groundwork for utilizing bacteria-focused therapies to complement traditional cancer treatments.

11 Apr 2024

Researchers create novel drug that can prevent flu-induced lung injury

Infection with the influenza virus leads to lung injury through inflammation over-activation that causes collateral damage to cells required for breathing.

10 Apr 2024

Systemic Inflammation Index: A new hope for autoimmune disease management

A routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of debilitating autoimmune diseases.

2 Apr 2024

Sensory neurons play pivotal role in orchestrating tissue repair and regeneration

Researchers from Monash University and Osaka University have unveiled a groundbreaking discovery regarding the pivotal role of sensory neurons in orchestrating tissue repair and regeneration, offering significant promise for patients with poorly healing tissues and diabetes.

27 Mar 2024

Unraveling the complexities of muscle repair in diabetes: A call for targeted research and therapies

Review outlines the impact of diabetes on skeletal muscle regeneration, highlighting the need for focused research and innovative therapies to tackle this growing health issue.

17 Mar 2024

Study unlocks the mystery of neonatal neutropenia in newborns

Compared to adults, newborns are highly susceptible to infections and these infections can cause serious health complications and even death.

15 Mar 2024

Study uncovers unexpected level of complexity hidden within neutrophils

In a study published in Cell on March 5, Prof. Zhang Xiaoming at the Shanghai Institute of Immunity and Infection (SIII) of the Chinese Academy of Sciences and Profs. Gao Qiang, Fan Jia and Yang Li at Fudan University have uncovered an unexpected level of complexity hidden within neutrophils, which were previously thought to be a relatively uniform population of short-lived immune cells.

6 Mar 2024

Neutrophil reprogramming promotes tumor growth in certain cancers

A new research study led by A*STAR.Singapore Immunology Network (A*STAR.SIgN) has found that neutrophils-;one of the most abundant white blood cells in our body-;change drastically in certain cancers, adopting a new function whereby they promote tumour growth.

23 Feb 2024