Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Lung cancer screening yields early diagnoses and increased cure rates in veterans

Among US veterans diagnosed with lung cancer through the Veterans Health Administration healthcare system, those who underwent screening before diagnosis were more likely to be diagnosed with earlier stage disease and had a higher cure rate than those who had not been screened.

10 Jun 2024

Glowing marker dye gives medics a 'second pair of eyes' during prostate cancer surgery

A glowing marker dye that sticks to prostate cancer cells could help surgeons to remove them in real-time, according to a study funded by Cancer Research UK.

10 Jun 2024

Unlocking the potential of ubiquitin-proteasome system in cancer treatment

A new editorial paper was published in Oncoscience (Volume 11) on May 6, 2024, entitled, "Restoring our ubiquitination machinery to overcome resistance in cancer therapy."

7 Jun 2024

Moffitt Cancer Center leads the way in revolutionizing cancer treatment with bioengineering

Bioengineering is revolutionizing cancer research, and Moffitt Cancer Center is at the forefront of this transformative movement.

7 Jun 2024

How increased mTOR activity shortens lifespan and promotes aging-related diseases

The reality of a population who is aging at an accelerated rate makes it a priority to understand what happens in the body over time, on a molecular scale.

7 Jun 2024

New biological mechanism uncovered for treating breast cancer metastasis to the brain

A study led by researchers from the University of Arizona Cancer Center at UArizona Health Sciences identified a biological mechanism that could lead to more effective treatments for breast cancer that has metastasized to the brain.

7 Jun 2024

New molecular portrait of KRAS in pancreatic cancer may guide better treatments

Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have established the most comprehensive molecular portrait of the workings of KRAS, a key cancer-causing gene or "oncogene," and how its activities impact pancreatic cancer outcomes.

6 Jun 2024

New hope for BCG-unresponsive bladder cancer patients with innovative combination therapy

In a groundbreaking advance that could revolutionize bladder cancer treatment, a novel combination of cretostimogene grenadenorepvec and pembrolizumab has shown remarkable efficacy in patients with Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer.

6 Jun 2024

‘Artificial lymph node’ shows potential to treat cancer

Johns Hopkins Medicine scientists say they have developed an artificial lymph node with the potential to treat cancer, according to a new study in mice and human cells.

6 Jun 2024

Precision medicine revolutionizes outcomes for high-risk pediatric cancer patients

In a world-first, Australian researchers and clinicians have shown that precision medicine – where treatment is tailored to an individual child's cancer – leads to significantly improved outcomes in children with high risk cancer.

6 Jun 2024

AI-powered liquid biopsy shows promise in early detection of lung cancer

Using artificial intelligence technology to identify patterns of DNA fragments associated with lung cancer, researchers from the Johns Hopkins Kimmel Cancer Center and other institutions have developed and validated a liquid biopsy that may help identify lung cancer earlier.

6 Jun 2024

Phase III trial highlights benefits of intensity modulated proton therapy for oropharyngeal cancer

According to preliminary data from a multi-institution Phase III trial led by researchers at The University of Texas MD Anderson Cancer Center, intensity modulated proton therapy (IMPT) achieved similar clinical outcomes and offered significant patient benefits when compared to traditional intensity modulated radiation therapy (IMRT) as part of chemoradiation treatment for patients with oropharyngeal (head and neck) cancer.

6 Jun 2024

Ultrasound technology breaks blood-brain barrier for glioblastoma treatment

In a major advance for the treatment of the deadly brain cancer glioblastoma, Northwestern Medicine scientists used ultrasound technology to penetrate the blood-brain barrier and provide a small dose of a chemotherapy and immunotherapy drug cocktail.

6 Jun 2024

Synergistic cytotoxicity in pancreatic cancer: HDAC, PARP inhibitors, and decitabine show promise

A new research paper was published in Oncotarget's Volume 15 on June 3, 2024, entitled, "Synergistic cytotoxicity of histone deacetylase and poly-ADP ribose polymerase inhibitors and decitabine in pancreatic cancer cells: Implications for novel therapy."

5 Jun 2024

Stanford study reveals link between adaptive myelination and drug addiction

Our brains, even in adulthood, continually adapt to what we do, strengthening or weakening neural pathways as we practice new skills or abandon old habits.

5 Jun 2024

Novel combination treatment outperforms standard therapy in patients with EGFR NSCLC

The combination of the antibody amivantamab and lazertinib, a drug targeting EGFR, shows better clinical benefits compared to standard treatment in patients with advanced or metastatic non-small cell lung cancer with EGFR gene mutations who also present one of these poor prognosti markers: brain and/or liver metastases, p53 gene co-mutations, or the presence of circulating tumor DNA.

4 Jun 2024

SU2C-SARC032 trial: Immunotherapy reduces relapse risk in soft tissue sarcoma by 43%

For the last three decades, breakthroughs have been sparse for soft tissue sarcomas, which are rare cancers that affect muscles, fat and other connective tissues.

4 Jun 2024

Experimental treatment for metastatic pancreatic cancer shows promise in phase 2 clinical trial

Clinicians at Georgetown University's Lombardi Comprehensive Cancer Center reported promising preliminary findings based on outcomes in the first six patients with metastatic pancreatic cancer enrolled in a phase 2 clinical trial of the experimental drug BXCL701 in combination with the immunotherapy drug pembrolizumab (Keytruda).

3 Jun 2024

Integrating PGx testing for personalized prostate cancer treatment

Prostate cancer (PC) is a significant health concern, being the second leading cause of death among American men.

31 May 2024

Stress and pain linked to worse outcomes in HER2-positive breast cancer patients

Secondary analyses of a phase 3 clinical trial have revealed that breast cancer patients who reported high levels of pain and stress were more likely than their study peers to experience worse invasive disease-free survival (iDFS) and worse overall survival (OS).

31 May 2024

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Oncology News and Research

Further Reading

Lung cancer screening yields early diagnoses and increased cure rates in veterans

Glowing marker dye gives medics a 'second pair of eyes' during prostate cancer surgery

Unlocking the potential of ubiquitin-proteasome system in cancer treatment

Moffitt Cancer Center leads the way in revolutionizing cancer treatment with bioengineering

How increased mTOR activity shortens lifespan and promotes aging-related diseases

New biological mechanism uncovered for treating breast cancer metastasis to the brain

New molecular portrait of KRAS in pancreatic cancer may guide better treatments

New hope for BCG-unresponsive bladder cancer patients with innovative combination therapy

‘Artificial lymph node’ shows potential to treat cancer

Precision medicine revolutionizes outcomes for high-risk pediatric cancer patients

AI-powered liquid biopsy shows promise in early detection of lung cancer

Phase III trial highlights benefits of intensity modulated proton therapy for oropharyngeal cancer

Ultrasound technology breaks blood-brain barrier for glioblastoma treatment

Synergistic cytotoxicity in pancreatic cancer: HDAC, PARP inhibitors, and decitabine show promise

Stanford study reveals link between adaptive myelination and drug addiction

Novel combination treatment outperforms standard therapy in patients with EGFR NSCLC

SU2C-SARC032 trial: Immunotherapy reduces relapse risk in soft tissue sarcoma by 43%

Experimental treatment for metastatic pancreatic cancer shows promise in phase 2 clinical trial

Integrating PGx testing for personalized prostate cancer treatment

Stress and pain linked to worse outcomes in HER2-positive breast cancer patients

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