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How Epstein-Barr virus shapes immune responses in multiple sclerosis

Study found that EBV-specific immune responses in MS patients showed higher IgG titers and cell-mediated reactions to EBV antigens compared to healthy controls, suggesting a complex role of EBV in MS development.

9 Jun 2024

Experts call for clear rules governing human embryo research

Clear rules governing human embryo research must be established to enable regulators, researchers and funders to assess whether stem cell-generated models should be considered as human embryos, two leading experts from The University of Manchester have argued.

8 Jun 2024

Curcumin nanoparticles show promise in treating neurodegenerative diseases

Review demonstrates curcumin's neuroprotective effects in neurodegenerative diseases, enhancing its potential through innovative nanoparticle formulations. This advancement could significantly improve treatments for diseases like Parkinson's, Alzheimer's, and Multiple Sclerosis.

6 Jun 2024

KFF Health News' 'What the Health?': Nursing home staffing rules prompt pushback

It's not surprising that the nursing home industry is filing lawsuits to block new Biden administration rules requiring minimum staffing at facilities that accept federal dollars.

6 Jun 2024

Cervix organ chips pave the way for next-generation studies on host-microbiome interactions

A group of researchers developed human Cervical Organ Chips to model the cervical interface.

4 Jun 2024

Family's rare telomere mutation reveals new insights into telomere flexibility and disease

Researchers discovered a rare telomere mutation (TTAGGT) in a family, revealing that human telomeres can tolerate non-canonical sequences, impacting telomere maintenance and disease.

4 Jun 2024

DefiniGEN and Atelerix collaborate to ship in vitro cell models internationally without the need for freezing or cryopreservation

DefiniGEN Ltd., and Atelerix Ltd., today announced they have successfully shipped in vitro liver models from the UK to a top tier pharma customer in the US. The agreement between the companies combines DefiniGEN’s mechanistically relevant iPSC hepatocytes (Opti-Heps) with Atelerix's hydrogel preservation technology, which prevents loss of function and enables even sensitive samples to remain stable at ambient temperatures for up to two weeks.

From Defini Gen 3 Jun 2024

Canagliflozin enhances senescent cell clearance, improving aging-related conditions

Whether sodium-glucose co-transporter 2 (SGLT2) inhibitors induce senolysis.

3 Jun 2024

Foam technology revolutionizes gene therapy, boosting efficiency and safety

Liquid foam gene delivery significantly enhances transfection efficiency and safety, offering a cost-effective alternative to conventional methods.

3 Jun 2024

Embryo selection based on polygenic risk scores can be unreliable and unethical

Polygenic risk scores (PRSs) are estimates of an individual's susceptibility to a specific complex trait obtained by aggregating the effects of dozens, thousands, and potentially millions of genetic variants associated with that specific trait into a single figure.

31 May 2024

Stem cell models unlock secrets of early human embryo development

A new study using stem cell-based models has shed new light on how the human embryo begins to develop, which could one day benefit the development of fertility treatment.

31 May 2024

Super-resolution microscopy offers high-resolution view of virus replication inside cells

A new, nano-scale look at how the SARS-CoV-2 virus replicates in cells may offer greater precision in drug development, a Stanford University team reports in Nature Communications.

31 May 2024

Single infusion of engineered T-cells achieves lasting asthma remission in mice

Researchers demostrate that durable asthma remission can be achieved with engineered and long-lived CAR T-cell treatment in mice.

31 May 2024

New recommendations designed to reframe the evaluation of in vitro diagnostic tests

Recommendations designed to reframe the evaluation of in vitro diagnostic tests have been published today by the Royal Statistical Society in its Series A journal.

30 May 2024

Miniaturized CRISPR protein opens door for gene therapy with adeno-associated virus

Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells.

30 May 2024

Cervix-on-a-Chip: A breakthrough model for studying women's health

Bacterial Vaginosis (BV) has been identified as one of the many unmet needs in women's health and affects more than 25% of reproductive-aged women.

30 May 2024

How tight binding between immune cells dictates T cell cancer-fighting ability

Immunotherapy, treatments that reinvigorate immune cells' anti-cancer activity or reprogram T cells to target cancer, has shown promise in treating leukemias but has not yet been realized in solid tumors.

30 May 2024

Advancing therapeutic insights: The impact of understanding cellular target engagement with NanoBRET® technology

In this Interview, NewsMedical speaks with Amy Landreman about NanoBRET® Technology and its role in cellular target engagement.

From Promega Corporation 30 May 2024

Evaluating the efficacy of harmol in treating herpes simplex virus-induced keratitis

The antiviral efficacy and therapeutic potential of harmol in treating herpes simplex virus type 1 (HSV-1) induced keratitis

29 May 2024

Targeting CD47 to improve osimertinib efficacy in EGFR mutant NSCLC

NSCLC is the leading cause of cancer deaths globally, with EGFR mutations being a common feature in these cancers.

28 May 2024

in vitro News and Research

How Epstein-Barr virus shapes immune responses in multiple sclerosis

Experts call for clear rules governing human embryo research

Curcumin nanoparticles show promise in treating neurodegenerative diseases

KFF Health News' 'What the Health?': Nursing home staffing rules prompt pushback

Cervix organ chips pave the way for next-generation studies on host-microbiome interactions

Family's rare telomere mutation reveals new insights into telomere flexibility and disease

DefiniGEN and Atelerix collaborate to ship in vitro cell models internationally without the need for freezing or cryopreservation

Canagliflozin enhances senescent cell clearance, improving aging-related conditions

Foam technology revolutionizes gene therapy, boosting efficiency and safety

Embryo selection based on polygenic risk scores can be unreliable and unethical

Stem cell models unlock secrets of early human embryo development

Super-resolution microscopy offers high-resolution view of virus replication inside cells

Single infusion of engineered T-cells achieves lasting asthma remission in mice

New recommendations designed to reframe the evaluation of in vitro diagnostic tests

Miniaturized CRISPR protein opens door for gene therapy with adeno-associated virus

Cervix-on-a-Chip: A breakthrough model for studying women's health

How tight binding between immune cells dictates T cell cancer-fighting ability

Advancing therapeutic insights: The impact of understanding cellular target engagement with NanoBRET® technology

Evaluating the efficacy of harmol in treating herpes simplex virus-induced keratitis

Targeting CD47 to improve osimertinib efficacy in EGFR mutant NSCLC

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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