Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Cardiovascular burden of TTR gene variant among Black carriers across mid to late-life

The key contribution of this study was to provide more accurate estimates of cardiovascular risk across mid to late life, compared to previously existing analyses.

15 May 2024

New study reveals brain clearance of toxins is reduced during sleep and anesthesia

The adipose-neural axis plays an important role in arrhythmogenesis.

15 May 2024

Researchers find beneficial effects of a novel drug in the management of myocardial infarction

Researchers from the Cardiac Regeneration and Heart Failure Research Group (ICREC) at the Germans Trias i Pujol Research Institute (IGTP) and the Heart Institute of the Germans Trias Hospital(iCor) have found beneficial effects of the novel drug Sacubitril/Valsartan in the management of myocardial infarction (MI).

14 May 2024

New risk assessment tool developed for predicting outcomes in heart failure patients

UVA Health researchers have developed a powerful new risk assessment tool for predicting outcomes in heart failure patients. The researchers have made the tool publicly available for free to clinicians.

14 May 2024

Investigational drug shows promise in increasing oxygen uptake for patients with heart condition

People with a common heart condition were able to use significantly more oxygen while exercising after taking an investigational drug in an international clinical trial, according to a study published today in the New England Journal of Medicine.

14 May 2024

Aficamten shows promise in enhancing exercise capacity in patients with hypertrophic cardiomyopathy

Even though mortality and hospitalization rates have improved, the quality of life for those living with hypertrophic cardiomyopathy (HCM) can be compromised with limiting symptoms such as exertional dyspnoea and decreased exercise capacity.

13 May 2024

Semaglutide improves heart failure symptoms and reduces loop diuretic dose

Semaglutide reduces the need for loop diuretic use and dose, and has positive effects on symptoms, physical limitations, and body weight in patients with heart failure with preserved ejection fraction (HFpEF) regardless of diuretic use, according to late breaking research presented today at Heart Failure 2024, a scientific congress of the European Society of Cardiology.

13 May 2024

Yogic practices enhance heart health and functional capacity in heart failure patients

Yoga focused on breathing, meditation, and relaxation is linked with symptom improvement in patients with heart failure, according to research presented today at Heart Failure 2024, a scientific congress of the European Society of Cardiology.

13 May 2024

Study shows clear benefit from COVID-19 vaccination for heart failure patients

Heart failure patients who are vaccinated against COVID-19 have an 82% greater likelihood of living longer than those who are not vaccinated, according to research presented today at Heart Failure 2024, a scientific congress of the European Society of Cardiology.

13 May 2024

Genetic variant increases heart failure risk and decreases longevity in Black Americans

Researchers at Brigham and Women’s Hospital and Duke University showed that a genetic variant, present in 3-4% of self-identified Black individuals in the U.S., increases the risk for both heart failure and death and contributes to significant decreases in longevity at the population level.

11 May 2024

Heightened risk of adverse neonatal outcomes from prenatal exposure to both cannabis and nicotine

A recent JAMA Network Open study found that combined prenatal use of nicotine and cannabis significantly increases risks for adverse perinatal outcomes, such as higher rates of hypertensive disease, preterm delivery, and elevated infant mortality compared to using neither or only one substance.

9 May 2024

Higher cardiorespiratory fitness levels linked to dramatically lower mortality and disease risks, study finds

A study in the British Journal of Sports Medicine, aggregating over 20.9 million observations, shows cardiorespiratory fitness (CRF) as a consistent predictor of reduced morbidity and mortality across various health outcomes in adults.

8 May 2024

Compound 12: A promising candidate for heart failure therapy with reduced glucose-lowering activity

Prior research showed that thoughtful structural modifications can dissociate the anti-heart failure activity from glucose-lowering effects.

8 May 2024

Breakthrough implantable cardiac pump offers hope for children awaiting heart transplants

A small, implantable cardiac pump that could help children await heart transplants at home, not in the hospital, has performed well in the first stage of human testing.

7 May 2024

Breakthrough imaging technique enhances evaluation of cardiac conditions and chest pain

A new imaging technique tested in patients could improve the evaluation of cardiac conditions and undiagnosed chest pain.

6 May 2024

MedStar Washington Hospital Center enrolls first U.S. patient in gene-editing therapy trial for heart disease

The first U.S. heart patient involved in a study for a new gene-editing therapy directly infused inside the body has successfully been enrolled at MedStar Washington Hospital Center.

6 May 2024

Sedentary behavior and low activity levels in childhood linked to heart strain in adolescence

According to a recent Finnish study, conducted at the University of Jyväskylä, high levels of sedentary behavior and physical inactivity from childhood strain the heart in adolescence.

6 May 2024

SMART study shows hemodynamic benefits of self-expanding valves in aortic stenosis patients

Additional analysis from the SMall Annuli Randomized To Evolut or SAPIEN (SMART) study demonstrated clinical non-inferiority of self-expanding valves (SEV) versus balloon-expandable valves (BEV) in aortic stenosis patients undergoing transcatheter aortic valve replacement (TAVR) and confirmed valve performance superiority over time based on hemodynamics.

3 May 2024

New transcatheter heart valve shows promise in treating aortic stenosis

Recent findings from a study on a transcatheter heart valve (THV) system, which includes a new class of transcatheter aortic valve, showed positive results in the device's ability to function as a healthy and natural aortic valve in patients with aortic stenosis (AS).

3 May 2024

High blood pressure in youth linked to elevated risk of heart conditions

Youth with high blood pressure are nearly four times more likely to be at long-term risk of serious heart conditions including stroke and heart attack, according to a new study.

3 May 2024

Heart Failure News and Research

Further Reading

Cardiovascular burden of TTR gene variant among Black carriers across mid to late-life

New study reveals brain clearance of toxins is reduced during sleep and anesthesia

Researchers find beneficial effects of a novel drug in the management of myocardial infarction

New risk assessment tool developed for predicting outcomes in heart failure patients

Investigational drug shows promise in increasing oxygen uptake for patients with heart condition

Aficamten shows promise in enhancing exercise capacity in patients with hypertrophic cardiomyopathy

Semaglutide improves heart failure symptoms and reduces loop diuretic dose

Yogic practices enhance heart health and functional capacity in heart failure patients

Study shows clear benefit from COVID-19 vaccination for heart failure patients

Genetic variant increases heart failure risk and decreases longevity in Black Americans

Heightened risk of adverse neonatal outcomes from prenatal exposure to both cannabis and nicotine

Higher cardiorespiratory fitness levels linked to dramatically lower mortality and disease risks, study finds

Compound 12: A promising candidate for heart failure therapy with reduced glucose-lowering activity

Breakthrough implantable cardiac pump offers hope for children awaiting heart transplants

Breakthrough imaging technique enhances evaluation of cardiac conditions and chest pain

MedStar Washington Hospital Center enrolls first U.S. patient in gene-editing therapy trial for heart disease

Sedentary behavior and low activity levels in childhood linked to heart strain in adolescence

SMART study shows hemodynamic benefits of self-expanding valves in aortic stenosis patients

New transcatheter heart valve shows promise in treating aortic stenosis

High blood pressure in youth linked to elevated risk of heart conditions

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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