Neurodegenerative Diseases News and Research

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Boosting mitochondrial health can reverse protein clumping in aging and Alzheimer's

It has long been known that a hallmark of Alzheimer's disease, and most other neurodegenerative diseases, is the clumping together of insoluble protein aggregates in the brain.

16 May 2024

Novel gene-delivery vehicle shows promise for treating brain disorders

In an important step toward more effective gene therapies for brain diseases, researchers from the Broad Institute of MIT and Harvard have engineered a gene-delivery vehicle that uses a human protein to efficiently cross the blood-brain barrier and deliver a disease-relevant gene to the brain in mice expressing the human protein.

16 May 2024

Genes and age reveal new insights into cognitive variability, study finds

Study examines the effects of specific genes and age on cognition, revealing potential for creating genotype- and cognition-stratified cohorts for future research.

16 May 2024

New therapy shows greater weight loss in mice by targeting brain's appetite center

A groundbreaking paper in Nature describes a promising new therapy for obesity that leads to greater weight loss in mice than existing medications.

16 May 2024

Repurposing human-approved drugs for prion disease treatment

Prions are the abnormal, pathogenic agents that are transmissible and are able to induce abnormal folding of specific normal cellular proteins.

16 May 2024

Study identifies a new biomarker for Alzheimer's disease in asymptomatic stages

A recent study led by the Molecular and Cellular Neurobiotechnology group at the Institute for Bioengineering of Catalonia (IBEC) and the University of Barcelona has identified a new biomarker for Alzheimer's disease in asymptomatic stages of the disease.

15 May 2024

Study reveals CNTN4 gene's role in neuronal development and Alzheimer's disease pathogenesis

New research has shed light on the complex interplay between cell proteins, and how they impact on neurons in neurodevelopmental disorders and Alzheimer's disease.

15 May 2024

Western diet linked to chronic diseases by gut microbiota disruption

The Western diet disrupts gut microbiota and gut barrier function, increasing the risk of non-communicable chronic diseases through chronic low-grade inflammation.

13 May 2024

Protein mechanics key to cell nucleus entry, study finds

Researchers at the Francis Crick Institute and King's College London have discovered that how soft or rigid proteins are in certain regions can dictate how fast or slow they enter the nucleus.

13 May 2024

Study uncovers alcohol's damaging effects on brain cells through oxidative stress

Alcohol exposure leads to accumulation of oxidatively damaged proteins in neuronal cells. Differentiated cells are more susceptible to alcohol-induced oxidative protein damage despite higher resistance to cytotoxicity.

9 May 2024

Ultra-processed foods linked to higher risk of death in long-term study

Higher consumption of most ultra-processed foods is linked to a slightly higher risk of death, with ready-to-eat meat, poultry, and seafood based products, sugary drinks, dairy based desserts, and highly processed breakfast foods showing the strongest associations, finds a 30-year US study in The BMJ today.

8 May 2024

FAU researchers receive grants to tackle Alzheimer's disease

Three Florida Atlantic University researchers at the forefront of Alzheimer's disease (AD) research have each received a $350,000 grant from the Florida Department of Health's "Ed and Ethel Moore Alzheimer's Disease Research Program."

8 May 2024

Study identifies neural compass in the human brain

A pattern of brain activity that helps prevent us from getting lost has been identified in a new study, published in Nature Human Behaviour.

6 May 2024

Researchers unveil mechanism enhancing cellular fitness against aging and neurodegeneration

Researchers at Duke University Medical Center discover a mechanism to enhance the fitness of cells against aging and neurodegenerative diseases. This finding will pave the way for novel therapeutic approaches in neuroprotection against aging-related disorders and neurodegeneration.

6 May 2024

Study reveals how photobiomodulation improves cognitive alterations from chronic stress

Some neurological disorders can be improved through photobiomodulation, a non-invasive technique based on the application of low-intensity light to stimulate altered functions in specific regions of the body.

2 May 2024

Columbia researchers uncover brain's ability to control inflammation

The brain can direct the immune system to an unexpected degree, capable of detecting, ramping up and tamping down inflammation, shows a new study in mice from researchers at Columbia's Zuckerman Institute.

2 May 2024

Parkinson’s UK invests £2.1 million in Neumora Therapeutics for preclinical testing of new Parkinson’s drug

Parkinson’s UK is investing £2.1million to support Neumora Therapeutics to carry out preclinical testing of NMRA-NLRP3, a NLRP3 inhibitor with the potential to reduce inflammation and protect brain cells in Parkinson’s. NLRP3 is a protein that plays a role in regulating a number of inflammatory processes that are believed to contribute to the damage to brain cells that underlies Parkinson’s.

27 Apr 2024

Diet's impact on gut bacteria offers new clues in Parkinson's disease management

Researchers find that diet significantly influences the gut microbiome in Parkinson's disease patients, potentially affecting disease progression and symptoms.

25 Apr 2024

Synthetic nanomaterial could be an effective tool for treating neurodegenerative diseases

A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for treating Alzheimer's and other neurodegenerative diseases.

25 Apr 2024

Researchers identify a ‘gene module’ involved in both depression and cardiovascular disease

Depression and cardiovascular disease (CVD) are serious concerns for public health. Approximately 280 million people worldwide have depression, while 620 million people have CVD. It has been known since the 1990s that the two diseases are somehow related.

25 Apr 2024

Neurodegenerative Diseases News and Research

Boosting mitochondrial health can reverse protein clumping in aging and Alzheimer's

Novel gene-delivery vehicle shows promise for treating brain disorders

Genes and age reveal new insights into cognitive variability, study finds

New therapy shows greater weight loss in mice by targeting brain's appetite center

Repurposing human-approved drugs for prion disease treatment

Study identifies a new biomarker for Alzheimer's disease in asymptomatic stages

Study reveals CNTN4 gene's role in neuronal development and Alzheimer's disease pathogenesis

Western diet linked to chronic diseases by gut microbiota disruption

Protein mechanics key to cell nucleus entry, study finds

Study uncovers alcohol's damaging effects on brain cells through oxidative stress

Ultra-processed foods linked to higher risk of death in long-term study

FAU researchers receive grants to tackle Alzheimer's disease

Study identifies neural compass in the human brain

Researchers unveil mechanism enhancing cellular fitness against aging and neurodegeneration

Study reveals how photobiomodulation improves cognitive alterations from chronic stress

Columbia researchers uncover brain's ability to control inflammation

Parkinson’s UK invests £2.1 million in Neumora Therapeutics for preclinical testing of new Parkinson’s drug

Diet's impact on gut bacteria offers new clues in Parkinson's disease management

Synthetic nanomaterial could be an effective tool for treating neurodegenerative diseases

Researchers identify a ‘gene module’ involved in both depression and cardiovascular disease

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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