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RPGRIP1L gene expression levels can be a potential prognostic marker for invasive breast cancer

A protein called retinitis pigmentosa GTPase regulator interacting protein 1-like (RPGRIP1L) performs various functions that are important for development and for health throughout life, and mutations in the RPGRIP1L gene have been linked to different diseases.

15 May 2024

New PET imaging biomarker Gal-1 predicts tumor responses to immunotherapy

The protein galectin-1 (Gal-1) has been identified as a new PET imaging biomarker for immune checkpoint blockade (ICB) therapy, allowing physicians to predict the tumor responses before beginning treatment.

15 May 2024

How AI is set to transform patient outcomes and surgical practices

Using artificial intelligence (AI) in surgery.

15 May 2024

Streamlining immune sensing and signaling dynamics research with INTEGRA Biosciences liquid handling tools

Immunologists in the Immune Sensing and Signaling Dynamics Group | ImmunoHUB at Instituto de Investigação e Inovação em Saúde (i3S) in Porto, Portugal, are using INTEGRA Biosciences laboratory tools to help further our understanding of the human immune system.

From INTEGRA Biosciences 15 May 2024

Study proposes a novel therapeutic avenue for tackling EHF-induced cholangiocarcinogenesis

This study is led by Dr. Yiming Luo (Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology) and Professor. Huifang Liang (Hepatic Surgery Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology).

14 May 2024

Research unveils the dual subdomain structure of the centromere

Researchers from the Kops group in collaboration with researchers from the University of Edinburgh, made a surprising new discovery in the structure of the centromere, a structure that is involved in ensuring that chromosomes are segregated properly when a cell divides.

14 May 2024

Exploring how intense ultrasound can release biological indicators of disease

Ultrasound imaging offers a valuable and noninvasive way to find and monitor cancerous tumors. However, much of the most crucial information about a cancer, such as specific cell types and mutations, cannot be learned from imaging and requires invasive and damaging biopsies.

14 May 2024

Curcuminoid compounds show promise against COVID-19 in neuronal cells

The effects of curcumin and curcuminoids on a human neuroblastoma cell line (SH-SY5Y) infected with SARS-CoV-2.

14 May 2024

Genetic analysis suggests the sudden emergence of threatening viruses

Suddenly they appear and - like the SARS-CoV-2 coronavirus - can trigger major epidemics: Viruses that nobody had on their radar.

13 May 2024

Plant virus-derived treatment shows promise against metastatic cancers

An experimental treatment made from a plant virus is effective at protecting against a broad range of metastatic cancers in mice, shows a new study from the University of California San Diego.

13 May 2024

New insights into Chaga mushroom's mechanisms for fighting oral cancer

The mechanisms behind the anti-tumor activity of Chaga mushroom extracts in HSC-4 human oral cancer cells.

13 May 2024

Expanding treatment horizons for hypermutated urothelial carcinomas beyond immunotherapy

A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, "Therapeutic opportunities for hypermutated urothelial carcinomas beyond immunotherapy."

10 May 2024

DoD grant awarded for investigating alternative polyadenylation in prostate cancer

A team led by Dr. Eddie Imada, assistant professor of research in pathology and laboratory medicine, has been awarded a three-year, $1.5 million United States Department of Defense grant for research on a cellular process called alternative polyadenylation and its role in prostate cancer.

10 May 2024

FDA-approved TIVDAK®: Targeting tissue factor in cervical cancer

On April 29th, 2024, the U.S. FDA granted full approval for Seagen Inc.'s TIVDAK® (tisotumab vedotin) targeting tissue factor (TF) for the treatment of patients with recurrent or metastatic cervical cancer who have progressed on or after chemotherapy. This marks a significant advancement in the therapeutic landscape for cervical cancer, highlighting the potential of antibody-drug conjugates (ADCs) in oncology.

From Sino Biological Inc. 10 May 2024

Combination immunotherapy treatment enhances immune response for people with malignant gliomas

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have pinpointed a combination immunotherapy treatment that enhances the immune response for people with malignant gliomas, an aggressive type of brain tumor that is fast growing and difficult to treat.

9 May 2024

Exploring microbiome dynamics in esophageal cancer

Esophageal cancer (EC) has two primary subtypes: esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC).

9 May 2024

Enhancing the ability of natural killer cells to combat hematologic malignancies

A new study reveals a groundbreaking approach to immunotherapy, demonstrating that blocking the interaction between the CD300A receptor and phosphatidylserine (PS) significantly enhances the ability of human natural killer (NK) cells to lyse hematologic malignancies (HMs).

9 May 2024

Researchers enhance CAR-T cells to target solid tumors

Researchers at the National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC) have shown that a breakthrough therapy for treating blood cancers can be adapted to treat solid tumors-;an advance that could transform cancer treatment.

8 May 2024

Intermittent fasting halts liver disease progression and reduces cancer risk

Fatty liver disease often leads to chronic liver inflammation and can even result in liver cancer. Scientists from the German Cancer Research Center (DKFZ) and the University of Tübingen have now shown in mice that intermittent fasting on a 5:2 schedule can halt this development.

8 May 2024

AI-driven model identifies potent cancer-killing immune cells for personalized immunotherapy

Using artificial intelligence, Ludwig Cancer Research scientists have developed a powerful predictive model for identifying the most potent cancer killing immune cells for use in cancer immunotherapies.

7 May 2024

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Tumor News and Research

RPGRIP1L gene expression levels can be a potential prognostic marker for invasive breast cancer

New PET imaging biomarker Gal-1 predicts tumor responses to immunotherapy

How AI is set to transform patient outcomes and surgical practices

Streamlining immune sensing and signaling dynamics research with INTEGRA Biosciences liquid handling tools

Study proposes a novel therapeutic avenue for tackling EHF-induced cholangiocarcinogenesis

Research unveils the dual subdomain structure of the centromere

Exploring how intense ultrasound can release biological indicators of disease

Curcuminoid compounds show promise against COVID-19 in neuronal cells

Genetic analysis suggests the sudden emergence of threatening viruses

Plant virus-derived treatment shows promise against metastatic cancers

New insights into Chaga mushroom's mechanisms for fighting oral cancer

Expanding treatment horizons for hypermutated urothelial carcinomas beyond immunotherapy

DoD grant awarded for investigating alternative polyadenylation in prostate cancer

FDA-approved TIVDAK®: Targeting tissue factor in cervical cancer

Combination immunotherapy treatment enhances immune response for people with malignant gliomas

Exploring microbiome dynamics in esophageal cancer

Enhancing the ability of natural killer cells to combat hematologic malignancies

Researchers enhance CAR-T cells to target solid tumors

Intermittent fasting halts liver disease progression and reduces cancer risk

AI-driven model identifies potent cancer-killing immune cells for personalized immunotherapy

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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