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Two new studies offer insights into the molecular biology of neuropsychiatric disease

Working under the umbrella of the PsychENCODE Consortium, the mental health research project established in 2015 by the National Institutes of Health, a team of Mount Sinai scientists has uncovered important new insights into the molecular biology of neuropsychiatric disease through two new studies published in a special issue of Science on Friday, May 24.

24 May 2024

Researchers produce advanced multidimensional maps of gene regulation networks in the brain

A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders.

24 May 2024

Immunotherapy-chemotherapy combo boosts survival for patients with metastatic colorectal cancer

A study led by UCLA Health Jonsson Comprehensive Cancer Center researchers found that using a combination of experimental immunotherapy drugs with chemotherapy significantly improves progression-free survival and overall survival for patients with metastatic colorectal cancer who have previously undergone standard chemotherapy treatment when compared to those who received the targeted therapy regorafenib alone.

24 May 2024

Phase 1 trial for EBC-129 progresses into dose expansion

The Experimental Drug Development Centre (EDDC), Singapore's national platform for drug discovery and development, is pleased to announce that the Phase 1 trial for EBC-129 has progressed into dose expansion.

24 May 2024

High-tech imaging and VR used for mapping the brain and understanding developmental disorders

Through high-tech imaging and virtual reality, a University of South Florida medical engineering professor is creating a detailed map of the brain that can be used to better understand developmental disorders, such as autism, and provide earlier, more effective treatments for brain injuries and diseases.

24 May 2024

Tattoos could be a risk factor for lymphoma, study suggests

A new study from Lund University in Sweden suggests that tattoos could be a risk factor for cancer in the lymphatic system, or lymphoma.

24 May 2024

New immunogenic strain of vaccinia virus unveils potent cancer therapy potential

Vaccinia viruses are therapeutic tools with different biomedical applications depending on the susceptibility characteristics.

24 May 2024

Comprehensive study provides new understandings of genomic influences on neuropsychiatric disease

A new analysis has revealed detailed information about genetic variation in brain cells that could open new avenues for the targeted treatment of diseases such as schizophrenia and Alzheimer's disease.

23 May 2024

In-vivo imaging to quantify collagen morphology in preclinical melanoma models during immunotherapy

Collagen, a major component of the extracellular matrix, plays a crucial role in tumor development.

23 May 2024

Physician-pharmacy integration not associated with change in the care of cancer patients

Integration of pharmacies with physician practices, where on-site pharmacies open at physician practice locations, is a growing trend in cancer treatment.

23 May 2024

New stem cell transplant approach may expand donor pool for high-risk blood cancer patients

A new treatment approach using an older drug may enable more patients with high-risk blood cancers to receive transplanted stem cells from unrelated, partially matched donors, according to a study conducted by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and colleagues.

23 May 2024

UCLA research connects genetic risk and brain changes in autism

A groundbreaking study led by UCLA Health has unveiled the most detailed view of the complex biological mechanisms underlying autism, showing the first link between genetic risk of the disorder to observed cellular and genetic activity across different layers of the brain.

23 May 2024

Ketogenic diet shows promise in treating anxiety, depression, and other mental health disorders, study finds

Research suggests the ketogenic diet may offer benefits in managing anxiety, depression, stress, schizophrenia, and bipolar disorder, but more clinical trials are needed to confirm its efficacy.

23 May 2024

Cherries and berries: Nature’s sweet remedy for a healthy heart

Research paper reviews the cardiovascular benefits of phenolic compounds in cherries and berries, highlighting their potential to reduce inflammation, oxidative stress, and improve lipid profiles. Regular consumption of these fruits can significantly lower the risk of cardiovascular diseases.

23 May 2024

Flavonoid-rich diet slashes type 2 diabetes risk by up to 28%, new study reveals

Increasing the intake of flavonoid-rich foods significantly reduces the risk of developing type 2 diabetes, according to a study in Nutrition & Diabetes.

23 May 2024

Study sheds light on intricate differences in the brains of people with PTSD and depression

Stress-related disorders like post-traumatic stress disorder and clinical depression are complex conditions influenced by both genetics and our environment.

23 May 2024

New understanding of cancer drug's ability to prevent fat buildup in the liver

University of Oklahoma researchers have deepened their understanding of a drug's ability to prevent fat buildup in the liver, a condition that often occurs with obesity and can lead to serious fatty liver disease.

23 May 2024

Study demonstrates causal link between microbial factors and dysfunction of ISCs in colitis

In a study published in Cell Host & Microbe, a research team led by Prof. PAN Wen from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences, in collaboration with research teams led by Prof. ZHU Shu and Prof. SONG Xinyang, demonstrated the causal link between microbial factors and dysfunction of intestinal stem cells (ISCs) in colitis.

23 May 2024

New genetic discoveries offer hope for targeted lupus therapies

Lupus is a lifelong, often painful and occasionally lethal autoimmune disease. Few treatments exist today beyond powerful steroids to knock down a patient's immune system -; a therapy that has its own serious risks.

23 May 2024

e-QuoL project: Digital tools for young cancer survivors' follow-up care

The "e-QuoL" project will develop a variety of digital tools to assist young cancer survivors manage their health and their follow-up care.

23 May 2024

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Medical Condition News

Two new studies offer insights into the molecular biology of neuropsychiatric disease

Researchers produce advanced multidimensional maps of gene regulation networks in the brain

Immunotherapy-chemotherapy combo boosts survival for patients with metastatic colorectal cancer

Phase 1 trial for EBC-129 progresses into dose expansion

High-tech imaging and VR used for mapping the brain and understanding developmental disorders

Tattoos could be a risk factor for lymphoma, study suggests

New immunogenic strain of vaccinia virus unveils potent cancer therapy potential

Comprehensive study provides new understandings of genomic influences on neuropsychiatric disease

In-vivo imaging to quantify collagen morphology in preclinical melanoma models during immunotherapy

Physician-pharmacy integration not associated with change in the care of cancer patients

New stem cell transplant approach may expand donor pool for high-risk blood cancer patients

UCLA research connects genetic risk and brain changes in autism

Ketogenic diet shows promise in treating anxiety, depression, and other mental health disorders, study finds

Cherries and berries: Nature’s sweet remedy for a healthy heart

Flavonoid-rich diet slashes type 2 diabetes risk by up to 28%, new study reveals

Study sheds light on intricate differences in the brains of people with PTSD and depression

New understanding of cancer drug's ability to prevent fat buildup in the liver

Study demonstrates causal link between microbial factors and dysfunction of ISCs in colitis

New genetic discoveries offer hope for targeted lupus therapies

e-QuoL project: Digital tools for young cancer survivors' follow-up care

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Why use light scattering to analyze proteins and viral vectors?

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