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Purified components of ginger help asthma patients breathe more easily

Gourmands and foodies everywhere have long recognized ginger as a great way to add a little peppery zing to both sweet and savory dishes; now, a study from researchers at Columbia University shows purified components of the spicy root also may have properties that help asthma patients breathe more easily. [More]
Takeda, Lundbeck announce presentation of data from four studies that evaluate vortioxetine for MDD

Takeda, Lundbeck announce presentation of data from four studies that evaluate vortioxetine for MDD

Takeda Pharmaceutical Company Limited and H. Lundbeck A/S today announced that the companies will be presenting new data from four studies that evaluated effectiveness in treating the overall symptoms of depression in patients taking vortioxetine, an investigational agent under review with the U.S. Food and Drug Administration for the treatment of major depressive disorder. [More]

Preclinical study shows PLX cells may help reverse symptoms associated with preeclampsia

Could the answer to repairing the ailing placenta in preeclampsia lie within the stem cells of a healthy placenta? New promising evidence may lead scientists to answer that question. [More]
Taking strong anticholinergic doubles risk of developing cognitive impairment in older adults

Taking strong anticholinergic doubles risk of developing cognitive impairment in older adults

Research from the Regenstrief Institute, the Indiana University Center for Aging Research and Wishard-Eskenazi Health on medications commonly taken by older adults has found that drugs with strong anticholinergic effects cause cognitive impairment when taken continuously for as few as 60 days. [More]
Scientists discover how Alzheimer's pharmaceuticals sharpen the brain's performance

Scientists discover how Alzheimer's pharmaceuticals sharpen the brain's performance

Scientists at the Virginia Tech Carilion Research Institute have discovered how the predominant class of Alzheimer's pharmaceuticals might sharpen the brain's performance. [More]
Study: Stem cell transplant heals neurological deficits in mice

Study: Stem cell transplant heals neurological deficits in mice

For the first time, human embryonic stem cells have been transformed into nerve cells that helped mice regain the ability to learn and remember. [More]
Review finds drugs, vitamin supplements may not help prevent cognitive decline in seniors

Review finds drugs, vitamin supplements may not help prevent cognitive decline in seniors

A review of published research has found no evidence that drugs, herbal products or vitamin supplements help prevent cognitive decline in healthy older adults. [More]
Scientists develop pig brain model to study human brain development

Scientists develop pig brain model to study human brain development

A mutual curiosity about patterns of growth and development in pig brains has brought two University of Illinois research groups together. Animal scientists Rod Johnson and Ryan Dilger have developed a model of the pig brain that they plan to use to answer important questions about human brain development. [More]
Antipsychotic drugs associated with increased risk of stroke in the elderly

Antipsychotic drugs associated with increased risk of stroke in the elderly

Antipsychotic administration in the elderly is associated with an increased risk for cerebrovascular accident, more commonly known as stroke; a new study published in Biological Psychiatry provides additional insight into this important relationship. [More]
BCHE gene variant predicts extent of plaque deposits in Alzheimer's

BCHE gene variant predicts extent of plaque deposits in Alzheimer's

A study combining genetic data with brain imaging, designed to identify genes associated with the amyloid plaque deposits found in Alzheimer's disease patients, has not only identified the APOE gene -- long associated with development of Alzheimer's -- but has uncovered an association with a second gene, called BCHE. [More]

Study finds chemical cues that allow seals’ brain to remain half awake and asleep

A new study led by an international team of biologists has identified some of the brain chemicals that allow seals to sleep with half of their brain at a time. [More]

No proof of added benefit from aclidinium bromide in adults with COPD

The drug aclidinium bromide has been approved since October 2012 for widening the narrowed airways of adults with chronic-obstructive pulmonary disease (COPD). The German Institute for Quality and Efficiency in Health Care (IQWiG) has now examined the added benefit of the drug pursuant to the "Act on the Reform of the Market for Medicinal Products" (AMNOG). [More]

Study sheds new light on learning and memory-making

In experiments on rats outfitted with tiny goggles, scientists say they have learned that the brain's initial vision processing center not only relays visual stimuli, but also can "learn" time intervals and create specifically timed expectations of future rewards. [More]
Multiple vascular benefits in salt restriction

Multiple vascular benefits in salt restriction

Restricting salt intake reverses vascular endothelial dysfunction in people with moderately increased blood pressure, shows a randomized study published in the Journal of the American College of Cardiology. [More]
Botulinum toxin A more effective than intralesional steroids in treating plantar fasciitis

Botulinum toxin A more effective than intralesional steroids in treating plantar fasciitis

Plantar fasciitis is the most frequent cause of chronic heel pain, leaving many sufferers unable to put their best foot forward for months at a time. Now a Mexican study suggests that physicians should turn to Botox rather than steroids to offer patients the fastest road to recovery. [More]

Vanderbilt University, AstraZeneca partner to identify candidate drugs for major brain diseases

Today, AstraZeneca and Vanderbilt University announced they have signed a research collaboration agreement to identify candidate drugs aimed at treating psychosis and other neuropsychiatric symptoms associated with major brain diseases such as Alzheimer's disease and schizophrenia. [More]
Merck’s resubmission of the NDA for suggammadex sodium injection accepted for review by the FDA

Merck’s resubmission of the NDA for suggammadex sodium injection accepted for review by the FDA

Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced that the resubmission of the New Drug Application (NDA) for sugammadex sodium injection has been accepted for review by the U.S. Food and Drug Administration (FDA). Merck expects the FDA’s review to be completed in the first half of 2013. [More]

Antibody type prognostic for myasthenia gravis patients

Patients who have myasthenia gravis are more likely to have a severe form of the disease and more difficulty achieving remission if they are seropositive for antibodies to muscle-specific kinase, report researchers. [More]
Molecule imitating a virus may trigger inappropriate immune response

Molecule imitating a virus may trigger inappropriate immune response

Why would our immune system turn against our own cells? This is the question that the combined Inserm/CNRS/ Pierre and Marie Curie University/Association Institut de Myologie have strived to answer in their "Therapies for diseases of striated muscle", concentrating in particular on the auto-immune disease known as myasthenia gravis. [More]
Paroxetine could treat vascular complications of diabetes

Paroxetine could treat vascular complications of diabetes

University of Texas Medical Branch at Galveston researchers have discovered that the commonly used antidepressant drug paroxetine could also become a therapy for the vascular complications of diabetes. [More]