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Anticholinergic medications associated with pneumonia risk in older people

Anticholinergic medications associated with pneumonia risk in older people

Taking commonly used medications with anticholinergic effects is associated with a significantly higher risk for developing pneumonia in a study of more than 3,000 older Group Health patients living in the community--not in nursing homes. [More]
Nicotine metabolite supports learning, memory by amplifying action of primary chemical messenger

Nicotine metabolite supports learning, memory by amplifying action of primary chemical messenger

Nicotine's primary metabolite supports learning and memory by amplifying the action of a primary chemical messenger involved in both, researchers report. [More]
Study suggests introduction of specific NGF to prevent neuronal degradation in Alzheimer's patients

Study suggests introduction of specific NGF to prevent neuronal degradation in Alzheimer's patients

Scientists at Karolinska Institutet have evaluated a new Alzheimer's therapy in which the patients receive an implant that stimulates the growth of a certain type of nerve cell. The results, which are published in the scientific journal Alzheimer's & Dementia, suggest that the introduction of a nerve growth factor can prevent neuronal degradation in Alzheimer's patients. [More]
MGH, MIT researchers reveal how the brain controls different sleep states

MGH, MIT researchers reveal how the brain controls different sleep states

Researchers at Massachusetts General Hospital and Massachusetts Institute of Technology have added another piece to the complex puzzle of how the brain controls one of the most essential functions - sleep. [More]
Bionomics initiates BNC210 Phase 1b clinical trial in healthy volunteers

Bionomics initiates BNC210 Phase 1b clinical trial in healthy volunteers

Bionomics Limited has initiated a Phase 1b clinical trial in healthy volunteers of BNC210, the Company's drug candidate in development for the treatment of anxiety and depression. [More]
Researchers probe possibility of reversing medications' adverse cognitive effects

Researchers probe possibility of reversing medications' adverse cognitive effects

Whether the adverse cognitive effects of medications can be reversed is of significant importance to an aging population, their caregivers and their families, as well as to an overburdened health care system. [More]
Research explores effect of DBS treatments in animals with brain injuries

Research explores effect of DBS treatments in animals with brain injuries

The research, published in Behavioural Brain Research, was conducted by Pilar Segura and Ignacio Morgado (coordinators), Laura Aldavert and Marc Ramoneda, psychobiologists of the Institute of Neurosciences and the Department of Psychobiology and Health Sciences Methodology of the UAB and by Elisabet Kadar and Gemma Huguet, molecular biologists of the University of Girona, to explore the power of Deep Brain Stimulation treatments in the hypothalamus to recover the ability to learn and remember after a severe lesion of the amygdala. [More]
Study: Fear of terrorism, existential anxiety increase pulse rate and risk of death

Study: Fear of terrorism, existential anxiety increase pulse rate and risk of death

A new study of over 17,000 Israelis has found that long-term exposure to the threat of terrorism can elevate people's resting heart rates and increase their risk of dying. [More]
Wimpy antibody prevents more serious self-inflicted forms of kidney disease, researchers say

Wimpy antibody prevents more serious self-inflicted forms of kidney disease, researchers say

An antibody abundant in mice and previously thought to offer poor assistance in fighting against infection may actually play a key role in keeping immune responses in check and preventing more serious self-inflicted forms of kidney disease, researchers say. [More]
‘Neuroprotective’ effects of smoking disputed

‘Neuroprotective’ effects of smoking disputed

The apparent neuroprotective effect of smoking may simply be because ease of quitting smoking is a marker of prodromal Parkinson’s disease, say researchers. [More]
Researchers develop potential fast-acting "vaccine" for myasthenia gravis

Researchers develop potential fast-acting "vaccine" for myasthenia gravis

Nearly 60,000 Americans suffer from myasthenia gravis (MG), a non-inherited autoimmune form of muscle weakness. The disease has no cure, and the primary treatments are nonspecific immunosuppressants and inhibitors of the enzyme cholinesterase. [More]
U-M scientists launch $11.5 million effort to better understand cause of Parkinson's disease

U-M scientists launch $11.5 million effort to better understand cause of Parkinson's disease

Deep in the brains of the million Americans with Parkinson's disease, changes to their brain cells put them at high risk of dangerous falls -- a problem that resists even the most modern treatments. [More]
Review article provides novel insight into brain changes in alcohol-related sleep-wake disturbances

Review article provides novel insight into brain changes in alcohol-related sleep-wake disturbances

A review article published online in Behavioral Brain Research provides novel insight into changes that happen in the brain as a result of chronic alcohol exposure that can lead to disruptions in the sleep cycle. [More]
Tissue-level model of human airway musculature could pave way for patient-specific asthma treatments

Tissue-level model of human airway musculature could pave way for patient-specific asthma treatments

The majority of drugs used to treat asthma today are the same ones that were used 50 years ago. New drugs are urgently needed to treat this chronic respiratory disease, which causes nearly 25 million people in the United States alone to wheeze, cough, and find it difficult at best to take a deep breath. [More]
New study sheds light on relationship between schizophrenia and smoking stems

New study sheds light on relationship between schizophrenia and smoking stems

Schizophrenia is associated with increased rates and intensity of tobacco smoking. A growing body of research suggests that the relationship between schizophrenia and smoking stems, in part, from an effort by patients to use nicotine to self-medicate symptoms and cognitive impairment associated with the disease. [More]
Alternatives to cigarette smoking may still pose a risk to human health due to over-use

Alternatives to cigarette smoking may still pose a risk to human health due to over-use

Cigarette smoking kills approximately 440,000 Americans each year, according to the Centers for Disease Control and Protection. It's the leading cause of preventable death worldwide. In order to overcome this addiction, many people resort to nicotine replacement therapies. [More]
Blocking nerve signals could be effective treatment for stomach cancer

Blocking nerve signals could be effective treatment for stomach cancer

Research from Columbia University Medical Center shows that nerves may play a critical role in stomach cancer growth and that blocking nerve signals using surgery or Botox® (onabotulinumtoxinA) could be an effective treatment for the disease. [More]
Anti-cholinergic drugs could be responsible for decline in cognitive, physical function in elderly patients

Anti-cholinergic drugs could be responsible for decline in cognitive, physical function in elderly patients

Drugs widely prescribed to the elderly could be responsible for a decline in cognitive and physical function according to research from the University of East Anglia and the Regenstrief Institute. [More]
Protein once seen as promising anti-cancer compound helps to stabilize neural circuits

Protein once seen as promising anti-cancer compound helps to stabilize neural circuits

Researchers at UC San Francisco (UCSF) have discovered that endostatin, a protein that once aroused intense interest as a possible cancer treatment, plays a key role in the stable functioning of the nervous system. [More]
Scientists reveal secrets of cell membrane proteins

Scientists reveal secrets of cell membrane proteins

Rice University scientists have succeeded in analyzing transmembrane protein folding in the same way they study the proteins' free-floating, globular cousins. [More]