Acute Respiratory Distress Syndrome News and Research

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Study reveals how SARS-CoV-2 hijacks lung cells to drive COVID-19 severity

Researchers identified how SARS-CoV-2 targets and manipulates specific lung cells, using innovative techniques to trace the virus's impact on the cells' gene expression, revealing insights into early COVID-19 pathogenesis.

14 Apr 2024

Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

Research highlights the inflammatory impacts of ARDS on the heart, underscoring the role of immune responses in cardiovascular complications from viral infections, including COVID-19, and emphasizes the potential of TNF-α neutralizing therapy to mitigate these effects.

24 Mar 2024

SARS-CoV-2-associated ARDS can damage the heart without direct infection

SARS-CoV-2, the virus that causes COVID-19, can damage the heart even without directly infecting the heart tissue, a National Institutes of Health-supported study has found.

20 Mar 2024

Genetic key to milder COVID: Certain genes slash severity and death risk in older men

Study found that certain genetic variants in the IL1RN gene significantly reduce COVID-19-related inflammation and mortality in patients, with notable improvements observed in older men carrying specific single-nucleotide variants.

19 Mar 2024

Research uncovers mechanical explanation for instability in the lungs of ARDS patients

Researchers at the University of Minnesota Twin Cities may have discovered a mechanical explanation for instability observed in the lungs in cases of acute respiratory distress syndrome (ARDS), particularly in the aftermath of respiratory illnesses such as COVID-19 or pneumonia.

12 Mar 2024

Proteins regulating plasminogen-plasmin levels can help predict COVID-19 severity

The global impact of the COVID-19 pandemic on healthcare systems has been significant. The sudden surge in infected cases overwhelmed hospitals and disrupted routine healthcare services, thus further worsening public health.

7 Mar 2024

Scientists uncover a new doorway for SARS-CoV-2 into human cells

Research identifies the human transferrin receptor as an alternative pathway for SARS-CoV-2 infection, offering potential new targets for COVID-19 therapies.

27 Feb 2024

Study reveals how long COVID can affect brain function through vascular disruption

The neurological response to coronavirus disease 2019 (COVID-19) may be due to brain-brain barrier (BBB) disruption.

26 Feb 2024

New cell therapy shows promise for critically ill COVID-19 patients with ARDS

Promising trial results indicate that a new type of cell therapy could improve the prognosis of those who are critically ill with acute respiratory distress syndrome (ARDS) resulting from severe Covid-19.

6 Feb 2024

Short-acting antibody curbs cytokine storms with minimal side effects

Cytokines are chemical messengers that help the body get rid of invading bacteria and viruses, and control inflammation.

16 Jan 2024

Infammasomes provide a therapeutic target against human diseases

The structure of inflammasomes and their role in diseases.

9 Jan 2024

Study suggests iron accumulation plays a central role in senescence and fibrosis

Researchers investigated the association between cellular damage, iron buildup, senescence, and fibrosis.

18 Dec 2023

Revolutionizing critical care: the potential of gut microbiota therapeutics

The curative potential and limitations of gut microbiome-based therapeutics in critical illnesses.

13 Nov 2023

Does adding sigh breaths to the usual care of trauma patients receiving mechanical ventilation increase ventilator-free days?

Researchers investigated whether adding sigh breaths to standard care regimens of mechanically ventilated trauma patients increased ventilator-free days.

30 Oct 2023

$3.4 million grant awarded to identify therapeutic treatments for acute respiratory distress syndrome

A four-year, $3.4 million grant to investigate molecular mechanisms and therapeutic treatments for acute respiratory distress syndrome (ARDS) has been awarded to UTHealth Houston researchers by the National Heart, Lung, and Blood Institute, part of the National Institutes of Health.

26 Oct 2023

Study shows benefit of convalescent plasma in Covid-19 patients requiring artificial ventilation

In a study published in The New England Journal of Medicine, clinicians and researchers from the CHU of Liège and the University of Liège show that the administration of plasma taken from convalescent donors after infection with Sars-CoV-2 to patients suffering from acute respiratory distress syndrome requiring artificial mechanical ventilation significantly reduced mortality (10%).

25 Oct 2023

COVID-19 survivors face sleep battles, with ARDS patients hardest hit, study finds

A recent study in the "Journal of Clinical Medicine" explored the long-term effects on sleep and circadian rhythms in COVID-19 survivors who experienced acute respiratory distress syndrome (ARDS). Findings revealed that a year after hospital discharge, over 91% of these patients suffered poor sleep quality, with nearly 59% experiencing insomnia, highlighting the lasting impact of COVID-19 on sleep health.

24 Oct 2023

Long-term lung issues and lower quality of life plague COVID-19 survivors, new study warns

New research in Scientific Reports reveals that COVID-19 survivors, especially those who had severe or critical illness, face long-term lung complications and a reduced quality of life. The study recommends 6-monthly pulmonary function tests for these survivors to monitor for chronic lung damage.

15 Oct 2023

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

The research paper explores the multifaceted role of the IL-17 family in immune response, covering everything from infection control to pathological conditions like autoimmune diseases and cancer. Future therapies may exploit IL-17's unique signaling pathways to offer more targeted and cost-effective treatments.

12 Oct 2023

Researchers develop an improved way to test potential vaccines against bird flu

Researchers from the University of Pittsburgh and the National Institutes of Health (NIH) Vaccine Research Center have developed an improved way to test potential vaccines against bird flu. The report was published this week in the journal iScience.

29 Sep 2023