Adalimumab News and Research

Adalimumab is an injectable prescription drug used to treat diseases of the immune system; it is marketed by Abbot as Humira. It is one of three drugs that work by inhibiting the potent inflammatory molecule tumor necrosis factor-alpha (TNF-alpha); the others are etanercept (Enbrel) and infliximab (Remicade). Like etanercept and infliximab, adalimumab is a large protein molecule made with recombinant DNA technology. Adalimumab is a monoclonal antibody of the IgG1 subtype that has been "humanized", meaning that all of its components are derived from human molecules.

TNF therapy does not raise cancer risk in RA patients; overall cancer risk comparable to those not taking immunosuppressive drugs

29. October 2009 01:00

A recent study by Swedish researchers found that rheumatoid arthritis (RA) patients did not experience an elevated cancer risk in the first 6 years after starting anti-tumor necrosis factor (TNF) therapy. [More]

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Posted in: Medical Condition News | Pharmaceutical News

Tags: Adalimumab, Arthritis, Autoimmune Disease, Cancer, Etanercept, Hospital, Infliximab, Methotrexate, Rheumatism, Rheumatoid Arthritis, Rheumatology, TNF Blockers

Report on the future market potential for monoclonal antibodies

27. October 2009 08:28

Reportlinker Adds Monoclonal Antibodies: Pipeline Analysis and Competitive Assessment [More]

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Posted in: Pharmaceutical News

Tags: Adalimumab, Alzheimer's Disease, Antibody, Arthritis, Avastin, Bevacizumab, Biotechnology, Cancer, Cetuximab, Crohn's Disease, Eculizumab, Evolution, Genetics, Hodgkin's Lymphoma, Infliximab, Lymphoma, Macular Degeneration, Monoclonal Antibody, Multiple Sclerosis, Non-Hodgkin's Lymphoma, Psoriasis, Ranibizumab, Raptiva, Rheumatoid Arthritis, Rituximab, Transplant, Vectibix, Zevalin

RA patients who adhere to their prescription drug regimen have better outcome: Study

20. October 2009 04:15

Rheumatoid arthritis (RA) patients who regularly adhere to their prescription drug regimen have fewer emergency room and doctor visits and incur lower medical costs, according to research presented today by Medco Health Solutions, Inc. at the American College of Rheumatology's Annual Meeting in Philadelphia. [More]

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Posted in: Medical Condition News

Tags: Adalimumab, Arthritis, Biotechnology, Crohn's Disease, Etanercept, Life Expectancy, Prescription Drug, Psoriasis, Rheumatoid Arthritis, Rheumatology

New data on Phase 3 SIMPONI clinical trials for rheumatoid arthritis

19. October 2009 09:41

New long-term data from two pivotal, Phase 3 clinical trials showed that patients with active rheumatoid arthritis (RA) receiving SIMPONI(TM) (golimumab) every four weeks achieved sustained improvements in signs and symptoms and physical function response through one year. These new data were presented today at the 2009 American College of Rheumatology (ACR) Annual Scientific Meeting. [More]

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Posted in: Drug Trial News | Medical Condition News

Tags: Adalimumab, Ankylosing Spondylitis, Antibody, Arthritis, Blood Pressure, Breast Cancer, Bronchitis, Cancer, Cartilage, Cell, Cold Sores, Cough, Diabetes, Diarrhea, Education, Etanercept, Golimumab, Heart Failure, Hepatitis B, Hygiene, Immunology, Infliximab, Lupus, Lymphoma, Methotrexate, Monoclonal Antibody, Multiple Sclerosis, Nausea, Nephrology, Nervous System, Oncology, Psoriatic Arthritis, Rheumatoid Arthritis, Rheumatology, TNF Blockers, Tuberculosis, Vaccine, Virus, Vomiting, Weight Loss

More studies needed to compare the efficacy of different biologic drugs for RA, say researchers

7. October 2009 04:34

More studies that directly compare the effectiveness of different biologic drugs for rheumatoid arthritis (RA) are needed, say Cochrane Researchers. The researchers reviewed all previous Cochrane Systematic Reviews assessing the effectiveness of biologic disease-modifying drugs for treatment of RA and found that although all were very effective, there was little data on direct comparisons between the drugs that could help doctors decide which to prescribe. [More]

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Posted in: Medical Condition News

Tags: Abatacept, Adalimumab, Arthritis, Autoimmune Disease, Etanercept, Infliximab, Methotrexate, Rheumatoid Arthritis, Rituximab, Veterans Affairs

Comprehensive and practical overview of psoriasis

22. September 2009 06:00

Treatments for psoriasis often present a therapeutic challenge to physicians because, besides affecting the skin, psoriasis may be associated with various comorbidities (for instance, depression, psoriatic arthritis, Crohn's disease and, in severe psoriasis, metabolic syndrome and cardiovascular diseases). [More]

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Posted in: Medical Condition News

Tags: Adalimumab, Arthritis, Crohn's Disease, Cyclosporine, Depression, Etanercept, Infliximab, Metabolic Syndrome, Methotrexate, Psoriasis, Psoriatic Arthritis

Event to address rheumatoid arthritis

22. September 2009 05:45

26 men and women with RA from across europe honoured as they share their inspirational stories. Actress, artist and activist Jane Seymour will host the first My Day for RA European event in Barcelona, Spain this evening to recognise the daily challenges, hopes and achievements of people living with rheumatoid arthritis (RA). [More]

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Posted in: Medical Condition News

Tags: Adalimumab, Arthritis, Biotechnology, Bone, Cartilage, Etanercept, Hemophilia, Hospital, Methotrexate, Nervous System, Oncology, Rheumatoid Arthritis, Rheumatology

New report on the psoriasis market offered by Research and Markets

4. September 2009 05:15

Research and Markets (http://www.researchandmarkets.com/research/b8d445/commercial_insight) has announced the addition of the "Commercial Insight: Psoriasis - Intellectual property drives growth" report to their offering. [More]

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Posted in: Medical Condition News

Tags: Adalimumab, Arthritis, Calcitriol, Corticosteroid, Dermatology, Etanercept, Infliximab, Psoriasis, Raptiva, Rheumatoid Arthritis, Tuberculosis

Golimumab shows promise for rheumatoid arthritis

28. June 2009 21:37

Golimumab, a new tumour necrosis factor-α (TNF-α) inhibitor reduces the signs and symptoms of rheumatoid arthritis in patients who have previously received any other TNF-α inhibitor, and might be a good option for patients who have inadequate responses to one or two other TNF-α inhibitors, finds an Article published Online first and in this week's edition of The Lancet. [More]

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Posted in: Drug Trial News

Tags: Adalimumab, Etanercept, Golimumab, Infliximab, Rheumatoid Arthritis, TNF Blockers

Impact of Medicare Part D on access to and cost sharing for specialty biologic medications for beneficiaries with rheumatoid arthritis

1. June 2009 19:33

Biologic disease-modifying antirheumatic drugs (DMARDs) such as adalimumab, etanercept and infliximab are effective at reducing symptoms and slowing progression of rheumatoid arthritis (RA). These drugs act more quickly, require less laboratory monitoring, and are better tolerated than nonbiologic DMARDs, but they are also up to 100 times more expensive. [More]

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Posted in: Pharmaceutical News

Tags: Adalimumab, Arthritis, Biologics Drug / Agent, Etanercept, Infliximab, Medicare, Rheumatoid Arthritis

Musculoskeletal Center wins $2.2 million to study biologics safety

18. November 2008 22:12

The UAB Center for Education and Research on Therapeutics has won a $2.2 million federal grant to study the risks and benefits of a class of drugs called ‘biologics' -- genetically engineered agents targeting the immune system of patients with rheumatoid arthritis, Crohn's disease, psoriasis and other autoimmune disorders. [More]

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Posted in: Pharmaceutical News

Tags: Adalimumab, Arthritis, Biologics Drug / Agent, Bone, Crohn's Disease, Education, Etanercept, Immunology, Inflammatory Disease, Infliximab, Psoriasis, Rheumatoid Arthritis, Rheumatology, TNF Blockers

Adalimumab therapy may reduce health-care costs for Crohn's disease patients

12. November 2008 21:30

Inflammatory bowel disease (IBD) is a term that refers to both ulcerative colitis (UC) and Crohn's disease (CD). [More]

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Posted in: Medical Condition News

Tags: Adalimumab, Antibody, Anxiety, Cancer, Colon Cancer, Colorectal Cancer, Crohn's Disease, Depression, Diarrhea, Dysplasia, Gastroenterology, Genetics, Hepatology, Inflammatory Bowel Disease, Osteoporosis, TNF Blockers, Ulcerative Colitis, Weight Loss

First-ever international guidelines for the treatment of psoriatic arthritis

26. October 2008 22:59

Rheumatologists, dermatologists, and patient advocates have come together to publish the first-ever international guidelines for the treatment of psoriatic arthritis, a disease that mainly affects people who have psoriasis but also some people without it. [More]

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Posted in: Medical Condition News

Tags: Adalimumab, Anti-Inflammatory, Arthritis, Autoimmune Disease, Back Pain, Blood Pressure, Bone, Diabetes, Etanercept, Ibuprofen, Immunology, Infliximab, Methotrexate, Osteoarthritis, Psoriasis, Psoriatic Arthritis, Rheumatoid Arthritis, Rheumatology, Spine, Tennis Elbow, TNF Blockers

Discovery of new genes for inflammatory bowel disease in children

31. August 2008 19:38

Researchers have discovered two new genes that increase the risk of developing inflammatory bowel disease (IBD) in childhood. [More]

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Posted in: Child Health News

Tags: Adalimumab, Antibody, Chromosome, Chromosome 20, Chromosome 21, Chromosome 6, Crohn's Disease, DNA, Genetics, Genomics, Hospital, Inflammatory Bowel Disease, Infliximab, Monoclonal Antibody, Pediatrics, TNF Blockers, Ulcerative Colitis

Could arthritis wonder drugs provide clues for all disease?

17. July 2008 20:00

Drugs that have helped treat millions of rheumatoid arthritis sufferers may hold the key to many more medical conditions, including atherosclerosis - a leading cause of heart disease - says the researcher who jointly invented and developed them. [More]

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Posted in: Medical Research News

Tags: Adalimumab, Alcohol Addiction, Ankylosing Spondylitis, Arthritis, Atherosclerosis, Blood Vessel, Cholesterol, Crohn's Disease, Cytokines, Etanercept, Infliximab, Psoriasis, Psoriatic Arthritis, Rheumatoid Arthritis, Rheumatology, TNF Blockers, Ulcerative Colitis

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Adalimumab News and Research

TNF therapy does not raise cancer risk in RA patients; overall cancer risk comparable to those not taking immunosuppressive drugs

Report on the future market potential for monoclonal antibodies

RA patients who adhere to their prescription drug regimen have better outcome: Study

New data on Phase 3 SIMPONI clinical trials for rheumatoid arthritis

More studies needed to compare the efficacy of different biologic drugs for RA, say researchers

Comprehensive and practical overview of psoriasis

Event to address rheumatoid arthritis

New report on the psoriasis market offered by Research and Markets

Golimumab shows promise for rheumatoid arthritis

Impact of Medicare Part D on access to and cost sharing for specialty biologic medications for beneficiaries with rheumatoid arthritis

Musculoskeletal Center wins $2.2 million to study biologics safety

Adalimumab therapy may reduce health-care costs for Crohn's disease patients

First-ever international guidelines for the treatment of psoriatic arthritis

Discovery of new genes for inflammatory bowel disease in children

Could arthritis wonder drugs provide clues for all disease?

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