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The adrenal glands are the part of the body responsible for releasing three different classes of hormones. These hormones cont, controlling the "fight or flight" response to stress, maintaining pregnancy, initiating and controlling sexual maturation during childhood and puberty. The adrenal glands are also an important source of sex steroids, such as estrogen and testosterone.

Drug trial for OSI-906 begins

23. September 2009 03:50
TGen Clinical Research Services at Scottsdale Healthcare today announced the start of a clinical trial for a drug designed to combat adrenocortical carcinoma (ACC), a rare but deadly cancer that attacks the adrenal glands. [More]

Posted in: Drug Trial News

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OSI Pharmaceuticals initiates two clinical trials with OSI-906 oral insulin-like growth factor-1 receptor inhibitor

4. September 2009 04:47
OSI Pharmaceuticals, Inc. (NASDAQ: OSIP) announced today the initiation of two clinical trials with OSI-906, the Company’s potential first-in-class, oral insulin-like growth factor-1 receptor (IGF-1R) inhibitor. The first study is a Phase III, multi-center study that will evaluate the use of OSI-906 for patients with locally advanced or metastatic adrenocortical carcinoma (ACC). [More]

European Medicines Agency validates Schering-Plough's MAA for nomegestrol acetate/17 beta-estradiol

27. August 2009 06:32
Schering-Plough Corporation, (NYSE: SGP), today announced that the European Medicines Agency (EMEA) has validated (accepted for review) the company's Marketing Authorization Application (MAA) for a fixed-dose combination of mometasone furoate and formoterol fumarate for the maintenance treatment of asthma in patients 12 years of age and older. [More]

Biological mechanisms contribute to stress resilience

5. August 2009 22:09
It is important to understand what biological mechanisms contribute to an individual’s capacity to be resilient under conditions of extreme stress, such as those regularly experienced by soldiers, police, and firefighters. [More]

Posted in: Medical Research News

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DHEA supplement combined with vitamin D and calcium significantly improves spinal bone density in older women

12. May 2009 06:49
"The results of our study are very promising. Similar studies have demonstrated much smaller benefits for bone than we found. However, calcium and vitamin D deficiencies, which are present in half of older adults, may have prevented DHEA from improving bone density in the earlier studies," said Edward Weiss, Ph.D., associate professor of nutrition and dietetics at Saint Louis University's Doisy College of Health Sciences and lead author of the study. [More]

Waiting for biopsy results may adversely affect health

24. February 2009 20:57
Women who've had a breast biopsy know the anxiety of waiting for the results, but that stress may cause adverse health effects, according to a new study published in the March issue of Radiology. [More]

Posted in: Medical Research News

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Researchers find novel use for old compound in cancer treatment

19. January 2009 02:43
The compound, alpha-difluoromethylornithine or DFMO, targets the activity of a specific enzyme and, even in very limited doses, is effective in protecting against the malignancy in animal models. [More]

New technique produces genetically identical stem cells

1. July 2008 18:24
Adult cells of mice created from genetically reprogrammed cells-so-called induced pluripotent stem (IPS) stem cells-can be triggered via drug to enter an embryonic-stem-cell-like state, without the need for further genetic alteration. [More]

Posted in: Medical Research News

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Stress hormone impacts memory, learning in diabetic rodents

18. February 2008 12:07
Diabetes is known to impair the cognitive health of people, but now scientists have identified one potential mechanism underlying these learning and memory problems. [More]

Smoking and SIDS

30. January 2008 08:18
A new study sheds light on the relationship between women who smoke while pregnant or are exposed to second-hand smoke and an increased risk of SIDS to their babies. [More]

Posted in: Child Health News

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Radical and partial nephrectomy for kidney cancers

10. January 2008 06:39
A new Mayo Clinic study suggests that removing the entire kidney from younger patients with small kidney tumors may lead to decreased overall survival compared with an operation that removes the tumor but leaves the kidney intact. [More]

Posted in: Medical Procedure News

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A happy marriage bolsters a woman's physiological recovery from work

2. January 2008 04:42
That's the suggestion from a new UCLA study that tracked levels of cortisol, a key stress hormone, among 30 Los Angeles married couples involved in one of our age's trickiest juggling acts - raising kids when both parents work full time. [More]

Discovery of master switch that regulates blood pressure

2. November 2007 12:19
A team of Oregon Health & Science University researchers studying a rare form of hypertension has identified the mechanism by which they believe a protein complex in the kidney operates as a master switch that regulates blood pressure, a finding that has broad implications for the treatment of more common forms of hypertension. [More]

New research may show why some prostate cancer recurs after treatment

12. October 2007 03:01
Cancer researchers have long worked to understand why some prostate cancers recur after the use of therapies designed to stop the production of testosterone and other androgens that fuel cancer cell growth. [More]

Posted in: Medical Research News

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Low birth weight children may be at a greater risk of stress-related health problems as adults

27. September 2007 22:55
Findings from this study show that low birth weight (below the 10th percentile) can lead later in life to low concentrations of cortisol, a hormone that regulates stress response by adjusting blood pressure and blood sugar levels. [More]
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