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Anti-VEGF therapy benefits in wet AMD not sustained

Anti-VEGF therapy benefits in wet AMD not sustained

Real-world experience of anti-vascular endothelial growth factor therapy for patients with wet age-related macular degeneration suggests that initial improvements in visual acuity are not maintained over time. [More]
Submacular air injection aids tPA haemorrhage displacement

Submacular air injection aids tPA haemorrhage displacement

Submacular air injection with a microneedle is effective at facilitating the displacement of massive submacular haemorrhages dissolved with tissue plasminogen activator in patients with age-related macular degeneration, an interventional case series shows. [More]
Heavy metallic elements influence AMD progression

Heavy metallic elements influence AMD progression

Researchers report associations between age-related macular degeneration and five heavy metallic elements, in findings that highlight the detrimental effects of pollution but the possible benefits of essential elements supplementation. [More]
AMD severity and progression tracks across eyes

AMD severity and progression tracks across eyes

Age-related macular degeneration in one eye tracks the severity of it in the fellow eye at all stages of the disease, findings from the Beaver Dam Eye study show. [More]

No added benefit with pazopanib over ranibizumab for neovascular AMD

Pazopanib eye drops do not enhance visual outcomes in patients with neovascular age-related macular degeneration beyond those achieved with ranibizumab alone, study findings indicate. [More]

Risk factors predict geographic atrophy after anti-VEGF treatment of RAP

Researchers have found three factors that could identify which patients with retinal angiomatous proliferation receiving anti-vascular endothelial growth factor treatment are likely to develop geographic atrophy. [More]
hESC-derived cells offer source of macular tissue repair and replacement

hESC-derived cells offer source of macular tissue repair and replacement

Subretinal transplantation of retinal pigment epithelium derived from human embryonic stem cells appears to be a well-tolerated means of treating age-related macular degeneration and Stargardt’s macular dystrophy, suggest two open-label phase I/II studies. [More]

Envision presents awards for work in low vision rehabilitation

Envision presents the Lifetime Achievement Award from time-to-time to researchers whose careers have been marked by outstanding, creative and important contributions to low vision research... [More]

Parkinson's disease drug delays onset of age-related macular degeneration

L-DOPA, a routine drug taken by patients suffering from Parkinson's disease, has been found to delay the onset of age-related macular degeneration (AMD). The research is being presented at the 2015 Annual Meeting of the Association for Research in Vision and Ophthalmology this week in Denver, Colo. [More]

Trained nurses administer AMD treatments as safely and effectively as doctors

Nurses trained to deliver eye injections for patients with the wet form of age-related macular degeneration (AMD) administered the treatments as safely and effectively as doctors, according to a new study. The research is being presented at the 2015 Annual Meeting of the Association for Research in Vision and Ophthalmology this week in Denver, Colo. [More]
AIDS patients at increased risk of developing intermediate-stage AMD

AIDS patients at increased risk of developing intermediate-stage AMD

Patients with acquired immunodeficiency syndrome (AIDS) have a four-fold increase in their risk of developing intermediate-stage age-related macular degeneration (AMD) compared to people of the same age who are not infected with HIV, according to results from the Longitudinal Study of the Ocular Complications of AIDS (LSOCA) presented today at the 2015 ARVO Annual Meeting in Denver, CO. [More]
Fifth patient dosed in Benitec's TT-034 Phase I/IIa clinical trial for prevention of HCV infection

Fifth patient dosed in Benitec's TT-034 Phase I/IIa clinical trial for prevention of HCV infection

Benitec Biopharma, a biopharmaceutical company focused on providing potentially curative therapies with its proprietary gene-silencing technology called ddRNAi or "expressed RNAi," is pleased to advise that the fifth patient in the company's 'first in man', Phase I/IIa dose escalation clinical trial of TT-034 for hepatitis C virus (HCV) infection, has today, been dosed at the Duke Clinical Research Unit. [More]
OAO report calls for better care for people living with eye disease, vision problems in Ontario

OAO report calls for better care for people living with eye disease, vision problems in Ontario

By 2031, the number of Ontarians living with eye disease and vision problems, already in the millions, is expected to double. This leads to significant costs for Ontario's healthcare system, with vision loss already costing the province $7.3 billion annually. [More]
TSRI study provides new insight into preventing diseases that cause vision loss in adults

TSRI study provides new insight into preventing diseases that cause vision loss in adults

A new study from scientists at The Scripps Research Institute shows that nerve cells and blood vessels in the eye constantly "talk" to each other to maintain healthy blood flow and prevent disease. [More]
Blocking Slit2 protein prevents blood vessel development that causes vasoproliferative ocular diseases

Blocking Slit2 protein prevents blood vessel development that causes vasoproliferative ocular diseases

Vasoproliferative ocular diseases are responsible for sight loss in millions of people in the industrialised countries. Many patients do not currently respond to the treatment offered, which targets a specific factor, VEGF. A team of Inserm researchers at the Vision Institute (Inserm/CNRS/Pierre and Marie Curie University), in association with a team from the Yale Cardiovascular Research Center, have demonstrated in an animal model that blocking another protein, Slit2, prevents the pathological blood vessel development that causes these diseases. [More]
Current challenges in tackling macular degeneration: an interview with Mark Ackermann, AMD Alliance International

Current challenges in tackling macular degeneration: an interview with Mark Ackermann, AMD Alliance International

There are two forms of macular degeneration: the wet form and the dry form. The dry form is less challenging as it affects a smaller number of people and the disease progression is far slower... [More]
RetroSense Therapeutics receives Luis Villalobos Award

RetroSense Therapeutics receives Luis Villalobos Award

RetroSense Therapeutics, LLC, a Wayne State University start-up biotechnology company, has received the Luis Villalobos Award from the Angel Capital Association, the world's leading professional association for angel investors. [More]
Research: Stem cell injection may soon slow or reverse effects of age-related macular degeneration

Research: Stem cell injection may soon slow or reverse effects of age-related macular degeneration

An injection of stem cells into the eye may soon slow or reverse the effects of early-stage age-related macular degeneration, according to new research from scientists at Cedars-Sinai. Currently, there is no treatment that slows the progression of the disease, which is the leading cause of vision loss in people over 65. [More]
UC Davis' John S. Werner wins 2015 Verriest Medal from International Colour Vision Society

UC Davis' John S. Werner wins 2015 Verriest Medal from International Colour Vision Society

John S. Werner, a UC Davis neuroscientist and international authority on visual perception, has been selected to receive the 2015 Verriest Medal from the International Colour Vision Society for his contributions to understanding the structural and functional basis of color vision, how and why vision changes across the life span, and factors that contribute to loss of vision associated with disease. He will receive the award at the society's biennial symposium in Sendai, Japan, in July. [More]
Fujifilm enters into definitive agreement to acquire Cellular Dynamics International

Fujifilm enters into definitive agreement to acquire Cellular Dynamics International

FUJIFILM Holdings Corporation (President: Shigehiro Nakajima) and Cellular Dynamics International, Inc. (CEO: Robert J. Palay), a leading developer and manufacturer of fully functioning human cells in industrial quantities to precise specifications, today announced that the two companies have entered into a definitive agreement whereby Fujifilm will acquire CDI via an all-cash tender offer to be followed by a second step merger. [More]
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