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Imaging proteasome complex helps show target site for potential cancer drugs

Imaging proteasome complex helps show target site for potential cancer drugs

Scientists have pioneered the use of a high-powered imaging technique to picture in exquisite detail one of the central proteins of life - a cellular recycling unit with a role in many diseases. [More]
Researchers discover mechanism that regulates metabolism

Researchers discover mechanism that regulates metabolism

The protein complex mTORC1 is a central regulator of cell metabolism. In the active state, it stimulates anabolic processes and increases the production and storage of proteins and lipids. Researchers from the German Leibniz Institute for Age Research in Jena and the Dutch Ageing Institute ERIBA in Groningen discovered a mechanism how mTORC1 regulates metabolism: It controls the expression of a specific variant of the transcriptional regulator C/EBPβ. [More]
Inactivity affects muscular strength in young and older people

Inactivity affects muscular strength in young and older people

New research reveals that it only takes two weeks of not using their legs for young people to lose a third of their muscular strength, leaving them on par with a person who is 40-50 years their senior. The Center for Healthy Aging and the Department of Biomedical Sciences at the University of Copenhagen conducted the research. [More]
Newcastle University scientists document action spectrum of ultraviolet damage in skin cells

Newcastle University scientists document action spectrum of ultraviolet damage in skin cells

Scientists at Newcastle University have documented for the first time the DNA damage which can occur to skin across the full range of ultraviolet radiation from the sun providing an invaluable tool for sun-protection and the manufacturers of sunscreen. [More]
Digital map of ageing brain could aid diagnosis of Alzheimer's disease, other neurodegenerative disorders

Digital map of ageing brain could aid diagnosis of Alzheimer's disease, other neurodegenerative disorders

A digital map of the ageing brain could aid the diagnosis of Alzheimer's disease and other neurodegenerative disorders in older people, a study suggests. [More]
New study predicts outcomes of CV patients using polypill intervention

New study predicts outcomes of CV patients using polypill intervention

A new study published in the journal BMJ Open (May 2015) has demonstrated that the improved treatment adherence achievable using a fixed-dose combination polypill (atorvastatin, ramipril and low-dose aspirin) to prevent recurring myocardial infarction, can avoid up to 15% more fatal and non-fatal CV events, conferring potential savings to healthcare systems. [More]
ABC TV's science program impacts use of statins among Australians

ABC TV's science program impacts use of statins among Australians

More than 60,000 Australians are estimated to have reduced or discontinued their use of prescribed cholesterol-lowering statin medications following the airing of a two-part series critical of statins by ABC TV's science program, Catalyst, a University of Sydney study reveals in the latest Medical Journal of Australia. [More]
New therapy for osteoporosis may be in the pipeline

New therapy for osteoporosis may be in the pipeline

Researchers from The Scripps Research Institute (TSRI), Florida, have reported a novel therapeutic approach that could promote the formation of new bone cells in people suffering from bone loss. [More]

Study shows autophagic defects are linked to sarcopenia

Sarcopenia is the aging-related loss of skeletal muscle mass and strength. Preventing sarcopenia is important for maintaining a high quality of life (QOL) in the aged population. [More]
GBD analysis shows over 95% of global population has health problems

GBD analysis shows over 95% of global population has health problems

Just one in 20 people worldwide (4·3%) had no health problems in 2013, with a third of the world's population (2·3 billion individuals) experiencing more than five ailments, according to a major new analysis from the Global Burden of Disease Study (GBD) 2013, published in The Lancet. [More]
HEALTH-TECH project approved by European Commission to establish centre of excellence for healthy ageing

HEALTH-TECH project approved by European Commission to establish centre of excellence for healthy ageing

2015 June 4-5 the kick-off meeting of the project HEALTH-TECH is taking place at Kaunas University of Technology (KTU) Santaka Valley. The project is aimed at founding a centre of excellence for healthy ageing. [More]
Study explores how our intestinal tract changes as we age

Study explores how our intestinal tract changes as we age

Scientists and clinicians on the Norwich Research Park have carried out the first detailed study of how our intestinal tract changes as we age, and how this determines our overall health. [More]
Type 2 diabetes screening followed by treatment could reduce risk of cardiovascular disease, death

Type 2 diabetes screening followed by treatment could reduce risk of cardiovascular disease, death

Screening to identify Type 2 diabetes followed by early treatment could result in substantial health benefits, according to new research published today in Diabetes Care that combined large scale clinical observations and innovative computer modelling. [More]
Serotonin and TGF-beta pathways link diet to health and ageing

Serotonin and TGF-beta pathways link diet to health and ageing

Diet exerts a major impact on health and ageing. The nervous system plays an important role in this process but, thus far, how food signals are interpreted by the nervous system has been a mystery. [More]
Eating Mediterranean diet helps delay cognitive decline

Eating Mediterranean diet helps delay cognitive decline

Professor of Preventive Medicine at the University of Valencia Dolors Corella is part of the multidisciplinary team conducting the Predimed study, which has found that eating a Mediterranean diet, enriched with olive oil or nuts, helps delay cognitive decline. [More]
Psychologists plan to enhance online health information on lung cancer

Psychologists plan to enhance online health information on lung cancer

Psychologists are to improve online health information on lung cancer after research showed that family members are more likely to search online to encourage loved ones to seek help. [More]
Health interventions to boost exercise in older people could be more successful with age differentiation

Health interventions to boost exercise in older people could be more successful with age differentiation

Health interventions to increase exercise in older people could be more successful if they differentiated between people aged 65 to 79 years old and those over 80 years old. [More]
Study offers new insights into construction of nuclear pores in nuclear envelope

Study offers new insights into construction of nuclear pores in nuclear envelope

In a recent study, a team of researchers led by Alwin Köhler at the Max F. Perutz Laboratories (MFPL) belonging to the University of Vienna and the Medical University of Vienna offer new insights into how nuclear pores are constructed in the nuclear envelope. [More]
1 in 5 people to develop heart failure in developed countries

1 in 5 people to develop heart failure in developed countries

One person in five is expected to develop heart failure in developed countries, a disease with no cure but which is largely preventable. [More]
Brachytherapy improves overall survival for women with inoperable early stage endometrial cancer

Brachytherapy improves overall survival for women with inoperable early stage endometrial cancer

Women who have early stage endometrial cancer and are inoperable tend to live longer if they have been treated with brachytherapy with or without external beam radiation, according to new research to be presented at the 3rd ESTRO Forum in Barcelona, Spain, on Sunday. [More]
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