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New IMA device could improve diagnosis, treatment of chronic musculoskeletal pain

More than 100 million people across Europe suffer from chronic musculoskeletal pain, with an estimated 40 per cent undiagnosed. Ageing populations throughout Europe means that this only going to increase in the coming years. [More]
Scientists study role of protein oxidation in the ageing process

Scientists study role of protein oxidation in the ageing process

Research published in the journal Cell Reports challenges the most popular theory about why our bodies deteriorate in old age. Scientists know that as we grow older our cells accumulate particles, called free radicals. [More]
Possible link discovered between common medications and falls in older men

Possible link discovered between common medications and falls in older men

Serious falls are more than twice as likely in older men who take medicines with anti-cholinergic properties - according to new research from the University of East Anglia. [More]
Twenty Radboud researchers receive Veni grant as part of Innovational Research Incentives Scheme

Twenty Radboud researchers receive Veni grant as part of Innovational Research Incentives Scheme

Twenty young and promising researchers from Nijmegen - eleven from Radboud University and nine from Radboudumc - are each to receive up to 250,000. NWO (The Netherlands Organisation for Scientific Research) is awarding the Veni grant as part of the Innovational Research Incentives Scheme. [More]
New paper describes positive effects of CRAC channel inhibitors in animal models of acute pancreatitis

New paper describes positive effects of CRAC channel inhibitors in animal models of acute pancreatitis

Researchers from CalciMedica, Inc. and the University of Liverpool today announced the publication of a paper describing positive effects of calcium release-activated calcium (CRAC) channel inhibitors in animal models of acute pancreatitis. The paper, titled "Inhibitors of ORAI1 prevent cytosolic calcium-associated injury of human pancreatic acinar cells and acute pancreatitis in 3 mouse models" appears in the August edition of the journal Gastroenterology. [More]

People who grow up in working class family happier than people from higher class background

People who grew up in a working class family are more satisfied in later life than those from a higher class background according to new research from The University of Manchester. [More]
Six hot line sessions set to reveal latest research in cardiovascular disease at ESC Congress 2015

Six hot line sessions set to reveal latest research in cardiovascular disease at ESC Congress 2015

Six hot line sessions at ESC Congress 2015 are set to reveal the latest in cardiovascular disease research across a range of conditions and comorbidities. Hot topics include atrial fibrillation, pacing, acute myocardial infarction, heart failure, hypertension, diabetes mellitus, pharmacology and coronary artery disease. [More]
Study shows regions of genome underlying IBD consistent around the world

Study shows regions of genome underlying IBD consistent around the world

The first genetic study of inflammatory bowel disease (IBD) to include individuals from diverse populations has shown that the regions of the genome underlying the disease are consistent around the world. This study, conducted under the auspices of the International IBD Genetics Consortium, included nearly 10,000 DNA samples from people of East Asian, Indian or Iranian descent and an existing set of 86,640 samples drawn from across Europe, North America and Oceania. [More]
Accutronics’s latest whitepaper tackles issues facing battery design in medical, healthcare sectors

Accutronics’s latest whitepaper tackles issues facing battery design in medical, healthcare sectors

Battery manufacturer Accutronics is making available for download its latest whitepaper, which tackles the issues facing battery design, development and use in the medical and healthcare field. [More]
Discovery brings hope for people suffering from Parkinson's disease

Discovery brings hope for people suffering from Parkinson's disease

Scientists from Singapore's Nanyang Technological University and McLean Hospital and Harvard Medical School in the United States have found that existing anti-malaria drugs could be a potential treatment for Parkinson's disease. [More]
Study stresses importance of investigating telomeres to improve diagnoses, develop treatments for many diseases

Study stresses importance of investigating telomeres to improve diagnoses, develop treatments for many diseases

Studying telomeres, the structures that protect the ends of chromosomes, has become a key issue in biology. In recent years, not only has their relation to ageing been confirmed; defective telomeres seem to be linked to more and more illnesses, including many types of cancer. [More]
NHFD initiative significantly improves care, survival of older people with hip fracture in England

NHFD initiative significantly improves care, survival of older people with hip fracture in England

Substantial improvements in the care and survival of older people with hip fracture in England have followed the introduction of a collaborative national initiative to tackle the issue, according to a new study published in the Medical Care journal. [More]
Futura Medical develops new generation of topical pain relief

Futura Medical develops new generation of topical pain relief

Futura Medical has developed a "new generation" of topical pain relief with two products that target more active ingredients directly to the point of pain. The new products have the potential to transform the pain relief market, according to chief executive James Barder. [More]
Restrictive policies for blood transfusions could produce significant cost savings for NHS

Restrictive policies for blood transfusions could produce significant cost savings for NHS

Changing clinical thresholds for the single leading reason for blood transfusions could safely produce significant savings for the NHS, according to NHS Blood and Transplant research published in The Lancet tomorrow. [More]
Imaging proteasome complex helps show target site for potential cancer drugs

Imaging proteasome complex helps show target site for potential cancer drugs

Scientists have pioneered the use of a high-powered imaging technique to picture in exquisite detail one of the central proteins of life - a cellular recycling unit with a role in many diseases. [More]
Researchers discover mechanism that regulates metabolism

Researchers discover mechanism that regulates metabolism

The protein complex mTORC1 is a central regulator of cell metabolism. In the active state, it stimulates anabolic processes and increases the production and storage of proteins and lipids. Researchers from the German Leibniz Institute for Age Research in Jena and the Dutch Ageing Institute ERIBA in Groningen discovered a mechanism how mTORC1 regulates metabolism: It controls the expression of a specific variant of the transcriptional regulator C/EBPβ. [More]
Inactivity affects muscular strength in young and older people

Inactivity affects muscular strength in young and older people

New research reveals that it only takes two weeks of not using their legs for young people to lose a third of their muscular strength, leaving them on par with a person who is 40-50 years their senior. The Center for Healthy Aging and the Department of Biomedical Sciences at the University of Copenhagen conducted the research. [More]
Newcastle University scientists document action spectrum of ultraviolet damage in skin cells

Newcastle University scientists document action spectrum of ultraviolet damage in skin cells

Scientists at Newcastle University have documented for the first time the DNA damage which can occur to skin across the full range of ultraviolet radiation from the sun providing an invaluable tool for sun-protection and the manufacturers of sunscreen. [More]
Digital map of ageing brain could aid diagnosis of Alzheimer's disease, other neurodegenerative disorders

Digital map of ageing brain could aid diagnosis of Alzheimer's disease, other neurodegenerative disorders

A digital map of the ageing brain could aid the diagnosis of Alzheimer's disease and other neurodegenerative disorders in older people, a study suggests. [More]
New study predicts outcomes of CV patients using polypill intervention

New study predicts outcomes of CV patients using polypill intervention

A new study published in the journal BMJ Open (May 2015) has demonstrated that the improved treatment adherence achievable using a fixed-dose combination polypill (atorvastatin, ramipril and low-dose aspirin) to prevent recurring myocardial infarction, can avoid up to 15% more fatal and non-fatal CV events, conferring potential savings to healthcare systems. [More]
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