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Magic mushroom compound may offer potential new way for antidepressant research

Magic mushroom compound may offer potential new way for antidepressant research

Psilocybin – a hallucinogenic compound derived from magic mushrooms – may offer a possible new avenue for antidepressant research, according to a new study published in The Lancet Psychiatry today. [More]
Changes in the brain make people prone to alcoholism

Changes in the brain make people prone to alcoholism

The brain tissue of persons with alcohol dependence shows a variety of changes compared to non-alcoholic control persons. All alcoholics' brains share some characteristics, but some are exclusive to the brain tissue of anxiety-prone type 1 alcoholics or impulsive type 2 alcoholics, according to a recent study from the University of Eastern Finland. [More]
Nicotine metabolism linked with chronic alcohol abuse may contribute to poor smoking cessation rates

Nicotine metabolism linked with chronic alcohol abuse may contribute to poor smoking cessation rates

For smokers who are addicted to alcohol, chronic alcohol abuse may increase the rate of nicotine metabolism and contribute to poor smoking cessation rates. When smokers stop drinking the nicotine metabolism rates decline significantly, according to a study conducted by an international research team led by Roswell Park Cancer Institute. The research was a collaboration of scientists from Roswell Park, the University of California, San Francisco, and the Medical University of Silesia and Center of Addiction Treatment in Poland. [More]
UNC-Chapel Hill researchers identify functional brain circuit that controls alcohol binge drinking

UNC-Chapel Hill researchers identify functional brain circuit that controls alcohol binge drinking

Researchers at the University of North Carolina at Chapel Hill have identified a circuit between two brain regions that controls alcohol binge drinking, offering a more complete picture on what drives a behavior that costs the United States more than $170 billion annually and how it can be treated. [More]

Researchers use heavy and non-heavy drinking levels to evaluate effectiveness of alcohol treatment

One of the challenges in evaluating the effectiveness of alcohol treatment is determining what constitutes a "good" outcome or meaningful improvement. While abstinence at the end of treatment is clearly a good outcome, a focus on abstinence ignores the benefits of patients reducing their drinking to less problematic levels so that they can function better and incur fewer social costs. [More]
Motivational interviewing can help reduce risky use of pain pills

Motivational interviewing can help reduce risky use of pain pills

As America battles an epidemic of deaths from misused pain pills, a new study suggests an inexpensive way to cut risky use of these drugs by people who have a high chance of overdosing. [More]
Adults who use marijuana more likely to develop alcohol use disorder

Adults who use marijuana more likely to develop alcohol use disorder

Adults who use marijuana are five times more likely to develop an alcohol use disorder (AUD) --alcohol abuse or dependence-- compared with adults who do not use the drug. And adults who already have an alcohol use disorder and use marijuana are more likely to see the problem persist. [More]
Recreational drug and alcohol use can increase risk of poisoning-related hospital admissions

Recreational drug and alcohol use can increase risk of poisoning-related hospital admissions

Poisonings from recreational drug and alcohol use account for 9 percent of all poisoning-related hospital admissions, says a new University of Sydney study revealing that males and people under 30 are at greatest risk. [More]
Healthcare professionals urged to tackle alcohol misuse, reduce risk of colorectal cancer

Healthcare professionals urged to tackle alcohol misuse, reduce risk of colorectal cancer

Healthcare professionals across Europe are being urged to help reduce the risk of colorectal cancer (CRC) by taking positive action against alcohol misuse and dependence. [More]
MSU professor finds surprising results about drug use behaviors

MSU professor finds surprising results about drug use behaviors

Conducting an economic analysis of drug use is a particularly difficult endeavor, but for Michigan State University professor and economist Siddharth Chandra, it just meant taking a look at the history books. [More]
Mental health problems, negative peer influences linked to increased dating violence

Mental health problems, negative peer influences linked to increased dating violence

A new emergency department study from the University of Michigan Injury Center looks deeper at risk and protective factors among teenagers who report dating violence and alcohol use. [More]
Researchers one step closer to finding effective drug for alcohol dependence

Researchers one step closer to finding effective drug for alcohol dependence

Researchers at Karolinska Institutet and the Sahlgrenska Academy in Sweden might be one step closer to finding an effective drug for alcohol dependence. In two separate studies, they show that the so-called dopamine stabilizer OSU6162 can reduce the craving for alcohol in alcohol dependent people and normalises the level of dopamine in the brain reward system of rats that have consumed alcohol over a long period of time. [More]
Medication used for diabetes could be a valuable tool for treating alcohol dependence

Medication used for diabetes could be a valuable tool for treating alcohol dependence

A new study on mice and rats at Sahlgrenska Academy shows that a medication used for diabetes and obesity also could be a valuable tool for the treatment of alcohol dependence. [More]
Study reports use of new psychoactive drugs in US nationally representative survey

Study reports use of new psychoactive drugs in US nationally representative survey

In recent years, there has been an increase in emergence and use of a variety of new drugs, so-called "novel psychoactive substances" (NPS) in the US and worldwide. [More]
Variations in opioid receptor genes linked to neonatal abstinence syndrome severity in newborn babies

Variations in opioid receptor genes linked to neonatal abstinence syndrome severity in newborn babies

A new study led by researchers at Boston Medical Center indicates that variations in opioid receptor genes are associated with more severe neonatal abstinence syndrome (NAS) in newborn babies. The findings, published online in Drug & Alcohol Dependence, could help lead to the development of individualized treatment plans tailored to each infants' risk of requiring medication to curb their NAS symptoms, which could help improve these patients' outcomes and reduce how long some stay in the hospital. [More]
FDA accepts sNDA to review Brintellix clinical trial data for treatment of major depressive disorder

FDA accepts sNDA to review Brintellix clinical trial data for treatment of major depressive disorder

Takeda Pharmaceutical Company Limited (Takeda) and H. Lundbeck A/S (Lundbeck) announced today the U.S. Food and Drug Administration (FDA) has accepted a supplemental New Drug Application (sNDA) for review to add clinical data regarding the effect of Brintellix (vortioxetine) on certain aspects of cognitive function in adults with Major Depressive Disorder (MDD) to the current product label. [More]
More marijuana dispensaries associated with more marijuana-related hospitalization rates

More marijuana dispensaries associated with more marijuana-related hospitalization rates

People who live in areas of California with a higher density of marijuana dispensaries experience a greater number of hospitalizations involving marijuana abuse and dependence, a University of Pittsburgh Graduate School of Public Health analysis discovered. [More]
Legal regulations on alcohol consumption have preventive effect on young consumers

Legal regulations on alcohol consumption have preventive effect on young consumers

Young men are at risk from alcohol consumption. Regulations such as the minimum legal drinking age can protect them. As a national study headed by UZH scientists reveals: The more legal measures for alcohol prevention are enforced in a canton, the less young men drink excessively. However, this is not effective for high-risk consumers such as young men with a tendency towards sensation seeking or antisocial behavior. [More]
Housing First approach helps reduce alcohol-related problems among homeless people with mental illness

Housing First approach helps reduce alcohol-related problems among homeless people with mental illness

A "Housing First" approach, where homeless people with mental illness are provided with a place to live without preconditions such as sobriety or seeing a psychiatrist, coupled with intensive case management, helps to reduce alcohol-related problems, a new study has found. [More]
Cognitive behavioral therapy effective for insomnia with psychiatric and medical conditions

Cognitive behavioral therapy effective for insomnia with psychiatric and medical conditions

Cognitive behavioral therapy is a widely used nonpharmacologic treatment for insomnia disorders and an analysis of the medical literature by sleep researchers at Rush University Medical Center suggests it also can work for patients whose insomnia is coupled with psychiatric and medical conditions, according to an article published online by JAMA Internal Medicine. [More]
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