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Aldara (imiquimod) is a synthetic agent with immune response modifying activity. As an immune response modifier (IRM), imiquimod stimulates cytokine production, especially interferon production, and exhibits antitumor activity, particularly against cutaneous cancers. Imiquimod's proapoptotic activity appears to be related to Bcl-2 overexpression in susceptible tumor cells. Check for active clinical trials or closed clinical trials using this agent.

Graceway Pharmaceuticals acquires global rights to Gilead Sciences' GS 9191 anti-proliferative agent

7. November 2009 00:12
Graceway Pharmaceuticals, LLC, a portfolio company of GTCR Golder Rauner, LLC, today announced that the company has acquired from Gilead Sciences, Inc. the worldwide license, including related regulatory filings and intellectual properties, to Gilead’s investigational molecule, GS 9191, for topical use. GS 9191 is an anti-proliferative agent that works by inhibiting cellular DNA synthesis, leading to the induction of apoptosis, or programmed cell death. [More]

Posted in: Drug Trial News | Medical Condition News

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National campaign to raise awareness of actinic keratosis

24. October 2009 03:50
Driver Aric Almirola is lending his voice to a national public education program to raise awareness of actinic keratosis (AK) -- a potential early warning sign of skin cancer -- as well as the long-term consequences of sun damage over a lifetime. The national campaign, "Is it AK or OK?" is sponsored by Graceway Pharmaceuticals, LLC, in partnership with The Skin Cancer Foundation. [More]

Posted in: Medical Condition News

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Anadys Pharmaceuticals presents data showing ANA773 promotes anti-tumor activity of killer cells

18. April 2007 14:38
Anadys Pharmaceuticals presented data from an in vitro study showing that the active metabolite of ANA773 promotes natural killer (NK) cell-mediated anti-tumor response by inducing cytokine secretion, cytolysis of tumor cells and enhanced antibody-dependent cellular cytotoxicity (ADCC), during a poster presentation at the Annual Meeting of the American Association of Cancer Research (AACR) in Los Angeles. [More]

New cream treatment for common form of skin cancer

23. July 2004 07:25
The US Food and Drug Administration has approved a new treatment for some people with a very common form of skin cancer. Imiquimod cream, sold as Aldara, can now be used to treat superficial basal cell carcinoma. [More]

Posted in: Pharmaceutical News

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3M granted FDA approval for cream to treat superficial basal cell carcinoma

16. July 2004 08:58
3M announced today that the U.S. Food and Drug Administration (FDA) has approved the first prescription therapy in nearly a decade for the treatment of superficial basal cell carcinoma (sBCC), a type of nonmelanoma skin cancer. [More]

FDA approval for skin cancer cream

14. April 2004 20:19
3M has received an "approvable" letter from the U.S. Food and Drug Administration (FDA) in response to its supplemental new drug application on Aldara (imiquimod) Cream, 5% for the treatment of superficial basal cell carcinoma (sBCC), a common form of non-melanoma skin cancer. [More]

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