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ARA 290 drug reduces neuropathic pain in type 2 diabetic patients

ARA 290 drug reduces neuropathic pain in type 2 diabetic patients

Molecular Medicine, a peer-reviewed biomedical journal published by the Feinstein Institute Press, published the results of a new study reporting clinically significant pain reduction in type 2 diabetic patients. In an exploratory study conducted by Araim Pharmaceuticals, a biotech company developing novel treatments for chronic diseases, investigators also observed improvements in metabolic control in patients administered ARA 290. [More]
UT Southwestern researchers identify cell signaling mechanism that plays vital role in brain cancer

UT Southwestern researchers identify cell signaling mechanism that plays vital role in brain cancer

UT Southwestern Medical Center neurology researchers have identified an important cell signaling mechanism that plays an important role in brain cancer and may provide a new therapeutic target. [More]
Researchers gain new insights into potential treatment for Alzheimer's disease

Researchers gain new insights into potential treatment for Alzheimer's disease

It is estimated that about 35 million people worldwide currently suffer from dementia and it is expected that the number will increase to 135 million by the year 2050. The disease is already one of the most common health problems in the elderly, which is why experts predict that the numbers of people affected will increase over time. [More]
Ten facts about Alzheimer's disease

Ten facts about Alzheimer's disease

Dr. Daniel Thomas will be conducting a ground-breaking study to determine if cognitive decline due to memory-destroying Alzheimer's disease can begin to be reversed in 90 days by combating the root causes using an innovative combination of diet, exercise, vitamin supplements, hormone therapy, and intravenous nutrition. [More]
Experts report three key topics that may make difference in the battle against Alzheimer's disease

Experts report three key topics that may make difference in the battle against Alzheimer's disease

Detection, prevention, and preclinical treatment are three key areas that may make a difference in the battle to reduce the rapid rise of new Alzheimer's disease (AD) cases every year. These three topics are the focus of an important new supplement to the Journal of Alzheimer's Disease. [More]
Neuroimaging markers have synergistic effect on cognitive decline

Neuroimaging markers have synergistic effect on cognitive decline

The Alzheimer disease neuroimaging markers β-amyloid and neurodegeneration have synergistic effects on the rate of cognitive decline in clinically normal people, research shows. [More]
Eli Lilly, AstraZeneca begin AZD3293 Phase II/III study for treatment of early Alzheimer's disease

Eli Lilly, AstraZeneca begin AZD3293 Phase II/III study for treatment of early Alzheimer's disease

Eli Lilly and Company and AstraZeneca today announced enrollment of the first patient into AMARANTH, a Phase II/III study of an oral beta secretase cleaving enzyme (BACE) inhibitor currently in development as a potential treatment for Alzheimer's disease. [More]

Bilingualism has protective effect in delaying Alzheimer's disease symptoms

A new study at Ghent University has established that the symptoms of Alzheimer disease (AD) manifest themselves about four to five years later in bilinguals as opposed to monolinguals. In bilinguals, the disease onset was estimated at the age of 77, while in monolinguals, this was at the age of 73. [More]
DTI may play role in assessing brain damage in early Alzheimer's disease

DTI may play role in assessing brain damage in early Alzheimer's disease

Changes in brain connections visible on MRI could represent an imaging biomarker of Alzheimer's disease, according to a new study presented today at the annual meeting of the Radiological Society of North America (RSNA). [More]
Drinking 3-5 cups of coffee per day may protect against Alzheimer’s Disease

Drinking 3-5 cups of coffee per day may protect against Alzheimer’s Disease

Drinking 3-5 cups of coffee per day may help to protect against Alzheimer’s Disease, according to research highlighted in an Alzheimer Europe session report published by the Institute for Scientific Information on Coffee, a not-for-profit organisation devoted to the study and disclosure of science related to coffee and health. [More]
Researchers discover two common genetic variants associated with memory performance

Researchers discover two common genetic variants associated with memory performance

In the largest study of the genetics of memory ever undertaken, an international researcher team including scientists from Boston University School of Medicine, have discovered two common genetic variants that are believed to be associated with memory performance. [More]
Protein that awakens brain from sleep may fight against Alzheimer's disease

Protein that awakens brain from sleep may fight against Alzheimer's disease

A protein that stimulates the brain to awaken from sleep may be a target for preventing Alzheimer's disease, a study by researchers at Washington University School of Medicine in St. Louis suggests. [More]
Special receptor signalling mediates astrocytic hyperactivity in  Alzheimer's disease mouse model

Special receptor signalling mediates astrocytic hyperactivity in Alzheimer's disease mouse model

It has long been known that astrocytes change their shapes as a consequence of Alzheimer's. Cells located near the "plaques", as the protein deposits typical for this disease are called, grow in size and form additional extensions. [More]
Stopping the death of synapses: an interview with Dr Soledad Galli

Stopping the death of synapses: an interview with Dr Soledad Galli

Synapses are the sites that connect neurons – sites where information is passed from one neuron to another. They are highly specialized structures and synaptic function is crucial for normal brain function. [More]
Anxiety can accelerate conversion to Alzheimer's disease for people with mild cognitive impairment

Anxiety can accelerate conversion to Alzheimer's disease for people with mild cognitive impairment

People with mild cognitive impairment (MCI) are at increased risk of converting to Alzheimer's disease within a few years, but a new study warns the risk increases significantly if they suffer from anxiety. [More]
Tau proteins spur neuron death in Alzheimer's disease

Tau proteins spur neuron death in Alzheimer's disease

New research points to tau, not amyloid-beta (Abeta) plaque, as the seminal event that spurs neuron death in disorders such as Alzheimer's disease. The finding, which dramatically alters the prevailing theory of Alzheimer's development, also explains why some people with plaque build-up in their brains don't have dementia. [More]
Mediterranean diet is good for your kidneys

Mediterranean diet is good for your kidneys

New research indicates that adopting a Mediterranean-style diet can reduce the risk of developing chronic kidney disease by 50%. [More]
New blood test could predict early onset Alzheimer’s disease with high accuracy

New blood test could predict early onset Alzheimer’s disease with high accuracy

The research team previously identified that changes in the brain occur two decades before patients show signs of dementia. These changes can be detected through expensive brain imaging procedures. [More]
Sleep apnea may affect peoples' ability to form new spatial memories

Sleep apnea may affect peoples' ability to form new spatial memories

Sleep apnea may affect your ability to form new spatial memories, such as remembering where you parked your car, new research led by NYU Langone Medical Center sleep specialists suggests. [More]
Roskamp Institute Discovers New Target For Drugs To Treat Alzheimer's Disease

Roskamp Institute Discovers New Target For Drugs To Treat Alzheimer's Disease

Scientists at the Roskamp Institute, a not-for-profit biomedical research facility specializing in Alzheimer's disease research, have isolated a key molecule that gives researchers a new drug target for the treatment of the progressive, irreversible neurological disorder. [More]