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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Protector of single cysteines discovered

21. November 2009 01:40
We've all read studies about the health benefits of having a life partner. The same thing is true at the molecular level, where amino acids known as cysteines are much more vulnerable to damage when single than when paired up with other cysteines. [More]

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Review of R&D and novel therapeutic challenges in neurological disorders

20. November 2009 04:39
Research and Markets (http://www.researchandmarkets.com/research/fae4d4/neurological_disea) has announced the addition of Decision Resources, Inc.'s new report "Neurological Disease: Early-Stage R&D and Dealmaking" to their offering. [More]

Alzheimer Research Forum reports on the highlights of the Society of Neuroscience conference

20. November 2009 04:22
Between 17-21 October 2009, the 39th annual conference of the Society of Neuroscience drew some 30,500 people to the great city of Chicago, which was more balmy than windy for the occasion. Your Alzforum reporters have been busy roaming the halls, buttonholing scientists for their comments on the presentations, and putting together reports on the most significant advances. [More]

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Health technology assessment to influence coverage of neurology drugs in most markets

20. November 2009 03:16
Research and Markets (http://www.researchandmarkets.com/research/60b63b/the_pricing_and_re) has announced the addition of Decision Resources, Inc.'s new report "The Pricing and Reimbursement Environment for Neurology Drugs" to their offering. [More]

Cognitive declines not linked to surgery in older adults, say researchers

20. November 2009 00:24
For years, it has been widely assumed that older adults may experience memory loss and other cognitive problems following surgery. But a new study from researchers at Washington University School of Medicine in St. Louis questions those assumptions. In fact, the researchers were not able to detect any long-term cognitive declines attributable to surgery in a group of 575 patients they studied. [More]

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Comprehensive report on neurodegenerative disorders market

19. November 2009 23:57
Research and Markets (http://www.researchandmarkets.com/research/5f3158/alzheimers_and_pa) has announced the addition of the "Alzheimer's and Parkinson's Diseases - A Global Update of Market Trends & Opportunities" report to their offering. [More]

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AFFiRiS to commence Phase II trial of its Alzheimer's vaccine candidate

19. November 2009 05:33
AFFiRiS AG will focus its Alzheimer's vaccine program on one product candidate at an unexpectedly early stage of development: the vaccine candidate AD02 is planned to enter into Phase II clinical trial early in 2010. This decision by the company immediately follows the completion of two Phase I trials with the candidates AD01 and AD02. The company based its fast decision on the first interim analysis of the secondary endpoints at the six month time point. [More]

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Possible new approach to slow the progression of cognitive decline in Down's syndrome

19. November 2009 04:41
A study by neuroscientist William C. Mobley, MD, PhD, chair of the Department of Neurosciences at the University of California, San Diego School of Medicine, and colleagues at Stanford University Medical School has demonstrated a possible new approach to slowing the inevitable progression of cognitive decline found in Down's syndrome. [More]

Study examines how dietary restriction and high-caloric diet influence biochemical responses

19. November 2009 03:26
Researchers at Mount Sinai School of Medicine set out to address a question that has been challenging scientists for years: How do dietary restriction-and the reverse, overconsumption-produce protective effects against aging and disease? [More]

Joint project focuses on finding ways to prevent dementia, including Alzheimer's disease

19. November 2009 02:36
Every two years, 2,000 senior Group Health patients check in with the Adult Changes in Thought (ACT) study. The joint project between Group Health Research Institute and the University of Washington (UW) focuses on finding ways to delay or prevent dementia, including Alzheimer's disease, and declines in memory and thinking. [More]

Halifax researcher wins Prix Galien Research Award

19. November 2009 02:13
Dr. Donald Weaver, a Halifax researcher with unmatched credentials, received the Prix Galien Research Award at a ceremony in Ottawa last night. Known as the Nobel Prize of pharmaceutical research, this award is the highest distinction worldwide for biopharmaceutical work, and the most prestigious in the field of Canadian pharmaceutical research and innovation. [More]

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Xeomin receives approval for post-stroke spasticity of upper limb in European countries

19. November 2009 01:42
Today, Merz Pharmaceuticals announced Xeomin®, the first botulinum toxin type A free from complexing proteins has been granted an extension of indication for post-stroke spasticity of the upper limb presenting with flexed wrist and clenched fist in adults in various European countries. [More]

Women with multiple sclerosis are less likely to have pregnancy complicaitons

19. November 2009 00:55
There is good news for women with multiple sclerosis (MS) who are pregnant or thinking about becoming pregnant. A new study shows that pregnant women with multiple sclerosis are only slightly more likely to have cesarean deliveries and babies with a poor prenatal growth rate than women who do not have MS. [More]

Gene that tells embryonic stem cells when to stop producing neurons identified

18. November 2009 07:00
Researchers from North Carolina State University have identified a gene that tells embryonic stem cells in the brain when to stop producing nerve cells called neurons. The research is a significant advance in understanding the development of the nervous system, which is essential to addressing conditions such as Parkinson's disease, Alzheimer's disease and other neurological disorders. [More]

New neuroimaging techniques yield new insights on Alzheimer's disease

18. November 2009 04:11
Brain imaging can offer a window into risk for diseases such as Alzheimer's disease (AD). A study conducted at the University of Kansas School of Medicine demonstrated that genetic risk is expressed in the brains of even those who are healthy, but carry some risk for AD. The results of this study are published in the November 2009 issue of the Journal of Alzheimer's Disease. [More]

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