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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.
Researchers uncover role of epigenetic changes in Alzheimer's disease

Researchers uncover role of epigenetic changes in Alzheimer's disease

A team led by researchers at the University of Exeter Medical School and King's College London has uncovered some of the strongest evidence yet that epigenetic changes in the brain play a role in Alzheimer's disease. [More]
Study shows bryostatin plays key role in slowing or reversing Alzheimer's disease

Study shows bryostatin plays key role in slowing or reversing Alzheimer's disease

Neurotrope, Inc. (OTCQB: NTRP) today announced that results from a new study, entitled, "PKCe Deficits in Alzheimer's Disease Brains and Skin Fibroblasts," published in the recent edition of the peer-reviewed Journal of Alzheimer's Disease and co-authored by Tapan K. Khan, Ph.D.; Abhik Sen, Ph.D.; Jarin Hongpaisan, Ph.D.; Chol S. Lim, Ph.D.; Thomas J. Nelson, Ph.D., and; Dr. Daniel L. Alkon, each of the Blanchette Rockefeller Neurosciences Institute (BRNI), provide further indication of the role that protein kinase C epsilon (PKCe) may play in the potential treatment of Alzheimer's disease (AD). [More]
Decision Resources expands disease-level coverage of Treatment Algorithms Insight Series

Decision Resources expands disease-level coverage of Treatment Algorithms Insight Series

Decision Resources has expanded its disease-level coverage of the Treatment Algorithms Insight Series, which examines U.S. physicians' prescribing behavior, to provide a quantitative analysis of an agent's penetration into each line of therapy. [More]
Researchers reveal how early changes in DNA methylation involved in Alzheimer's disease

Researchers reveal how early changes in DNA methylation involved in Alzheimer's disease

A new study led by researchers at Brigham and Women's Hospital (BWH) and Rush University Medical Center, reveals how early changes in brain DNA methylation are involved in Alzheimer's disease. [More]
Yizhijiannao granule may exert therapeutic effect by inhibiting neural cell apoptosis

Yizhijiannao granule may exert therapeutic effect by inhibiting neural cell apoptosis

Previous studies have shown that Yizhijiannao granule can enhance cognitive performance in Alzheimer's disease patients and Alzheimer's disease-model mice. [More]
Reducing brain levels of tau protein effectively blocks development of childhood epilepsy

Reducing brain levels of tau protein effectively blocks development of childhood epilepsy

Researchers at the Gladstone Institutes have shown that reducing brain levels of the protein tau effectively blocks the development of disease in a mouse model of Dravet syndrome, a severe intractable form of childhood epilepsy. [More]
Lead levels in foods prepared in aluminum pots from Cameroon exceed US guidelines for lead intake

Lead levels in foods prepared in aluminum pots from Cameroon exceed US guidelines for lead intake

Lead levels in foods prepared in aluminum pots from Cameroon exceed U.S. guidelines for lead consumption according to a new study published this month. [More]
Decline in daily functioning linked with Alzheimer's disease is related to alterations in brain activity

Decline in daily functioning linked with Alzheimer's disease is related to alterations in brain activity

Decline in daily functioning associated with Alzheimer's disease is related to alterations in activity in certain regions of the brain, according to a study published in the August 2014 issue of the Journal of Alzheimer's Disease. [More]
Researchers determine safety and effectiveness of neurostimulation to treat chronic pain

Researchers determine safety and effectiveness of neurostimulation to treat chronic pain

Chronic pain, which persists despite the fact that an injury has healed, can last for many months or years and may affect up to 15 percent of the adult population at any point in time. [More]
BCC Research report provides detailed analyses of global stem cell market

BCC Research report provides detailed analyses of global stem cell market

Reportlinker.com announces that a new market research report is available in its catalogue: The Global Market for Stem Cells. [More]
Global therapeutic market for BBB technologies expected to grow at 64.9% CAGR over 2014-2019

Global therapeutic market for BBB technologies expected to grow at 64.9% CAGR over 2014-2019

Reportlinker.com announces that a new market research report is available in its catalogue: Blood-Brain Barrier Technologies and Global Markets. [More]
Inovio Pharmaceuticals reports increased revenue in second quarter 2014

Inovio Pharmaceuticals reports increased revenue in second quarter 2014

Inovio Pharmaceuticals, Inc. today reported financial results for the quarter ended June 30, 2014. Total revenue was $3.8 million and $6.2 million for the three and six months ended June 30, 2014, compared to $786,000 and $2.2 million for the same periods in 2013. [More]
Scientists identify mechanism by which inherited neurological disease causes muscle weakness in men

Scientists identify mechanism by which inherited neurological disease causes muscle weakness in men

Researchers at University of California, San Diego School of Medicine have identified the mechanism by which a rare, inherited neurodegenerative disease causes often crippling muscle weakness in men, in addition to reduced fertility. [More]
People who develop depression, MCI after age 65 are more vulnerable for accelerated brain aging

People who develop depression, MCI after age 65 are more vulnerable for accelerated brain aging

People who develop depression and mild cognitive impairment (MCI) after age 65 are more likely to have biological and brain imaging markers that reflect a greater vulnerability for accelerated brain aging, according to a study conducted by researchers at the University of Pittsburgh School of Medicine. The findings were published online in Molecular Psychiatry. [More]
Infectious prion protein is marker for variant Creutzfeldt-Jakob disease

Infectious prion protein is marker for variant Creutzfeldt-Jakob disease

The misfolded and infectious prion protein that is a marker for variant Creutzfeldt-Jakob disease - linked to the consumption of infected cattle meat - has been detected in the urine of patients with the disease by researchers at The University of Texas Health Science Center at Houston (UTHealth) Medical School. [More]
People diagnosed with MCI are more likely to increase risk of developing dementia

People diagnosed with MCI are more likely to increase risk of developing dementia

In a long-term, large-scale population-based study of individuals aged 55 years or older in the general population researchers found that those diagnosed with mild cognitive impairment (MCI) had a four-fold increased risk of developing dementia or Alzheimer's disease (AD) compared to cognitively healthy individuals. [More]
Low levels of vitamin D may double dementia, Alzheimer's risks

Low levels of vitamin D may double dementia, Alzheimer's risks

In the largest study of its kind, researchers suggests that in older people, not getting enough vitamin D may double the risk of developing dementia and Alzheimer's disease. The study is published in the August 6, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
7.0T NMR spectroscopy detects lesions in hippocampal neurons of Alzheimer's disease

7.0T NMR spectroscopy detects lesions in hippocampal neurons of Alzheimer's disease

Magnetic resonance spectroscopy can quantitatively analyze in vivo abnormalities of biochemical metabolism within brain tissue in a noninvasive and non-radioactive manner. [More]
Whey protein drink can control erratic glucose levels associated with type 2 diabetes

Whey protein drink can control erratic glucose levels associated with type 2 diabetes

Blood sugar surges - after-meal glucose "spikes" - can be life threatening for the 29 million Americans with diabetes. Diabetic blood sugar spikes have been linked to cardiovascular disease, cancer, Alzheimer's disease, kidney failure, and retinal damage. [More]
Researchers study effect of alcohol on neural activity using fruit flies

Researchers study effect of alcohol on neural activity using fruit flies

Seeking eventual solutions to problems ranging from alcoholism, cancer and Alzheimer's to finding better ways to clean contact lenses and use Lego models to build bridges, University of Houston (UH) students devoted the summer to some serious scholarship. [More]