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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.
Lamin nucleoskeleton disordered in Alzheimer's

Lamin nucleoskeleton disordered in Alzheimer's

Brain cell death in Alzheimer's disease is linked to disruption of a skeleton that surrounds the nucleus of the cells, a researcher in the School of Medicine at The University of Texas Health Science Center at San Antonio said. [More]
People with traumatic brain injuries may have buildup of plaques related to Alzheimer's disease

People with traumatic brain injuries may have buildup of plaques related to Alzheimer's disease

A new study suggests that people with brain injuries following head trauma may have buildup of the plaques related to Alzheimer's disease in their brains. The research is published in the February 3, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
NJHF awards 30 grants for NJ researchers working on health-related research

NJHF awards 30 grants for NJ researchers working on health-related research

New Jersey Health Foundation has awarded 30 grants totaling more than $1 million for researchers in New Jersey who are working on health-related research that demonstrates exciting potential. [More]
Seafood consumption may benefit older adults at risk for Alzheimer's disease

Seafood consumption may benefit older adults at risk for Alzheimer's disease

New research published Feb. 2 in the Journal of the American Medical Association found that older adults with a major risk gene for Alzheimer's disease known as APOE?4 who ate at least one seafood serving per week showed fewer signs of Alzheimer's-related brain changes. In contrast, this association was not found in the brains of volunteers who ate fish weekly but did not carry the risk gene. [More]
Saliva gland test may help diagnose early Parkinson's disease

Saliva gland test may help diagnose early Parkinson's disease

Researchers from Mayo Clinic in Arizona and Banner Sun Health Research Institute have determined that testing a portion of a person's submandibular gland may be a way to diagnose early Parkinson's disease. The study was published this month in Movement Disorders, the official journal of the International Parkinson and Movement Disorders Society. [More]
Understanding crucial role of 'healthy' brain in preventing memory failures linked to Alzheimer's disease

Understanding crucial role of 'healthy' brain in preventing memory failures linked to Alzheimer's disease

The mechanisms underlying the stability and plasticity of neural circuits in the hippocampus, the part of the brain responsible for spatial memory and the memory of everyday facts and events, has been a major focus of study in the field of neuroscience. Understanding precisely how a "healthy" brain stores and processes information is crucial to preventing and reversing the memory failures associated with Alzheimer's disease (AD), the most common form of late-life dementia. [More]
Study reveals increased mortality risk following hypertensive disease of pregnancy

Study reveals increased mortality risk following hypertensive disease of pregnancy

In a study to be presented on Feb. 5 at 8 a.m. EST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in Atlanta, researchers will present findings from a study titled, Long-term mortality risk following hypertensive disease of pregnancy (HDP). [More]
FDA-approved blood pressure drug reduces cell damage linked to Alzheimer's disease

FDA-approved blood pressure drug reduces cell damage linked to Alzheimer's disease

In laboratory neuronal cultures, an FDA-approved drug used to treat high blood pressure reduced cell damage often linked to Alzheimer's disease, say researchers at Georgetown University Medical Center and the National Institutes of Health. [More]
Eisai's Halaven receives FDA approval for treatment of patients with metastatic liposarcoma

Eisai's Halaven receives FDA approval for treatment of patients with metastatic liposarcoma

Eisai Inc. announced today that the U.S. Food and Drug Administration approved Halaven (eribulin mesylate) Injection (0.5 mg per mL) for the treatment of patients with unresectable or metastatic liposarcoma who have received a prior anthracycline-containing regimen. [More]
Education level influences cognitive training outcomes in older adults

Education level influences cognitive training outcomes in older adults

The first study to investigate the effects of cognitive training on the cognitive functioning of older adults by education level has found that individuals with fewer than 12 years of schooling benefit more from cognitive training than their more highly educated counterparts. [More]
Brain-derived neurotrophic factor linked to slower cognitive decline in older people

Brain-derived neurotrophic factor linked to slower cognitive decline in older people

Older people with higher amounts of a key protein in their brains also had slower decline in their memory and thinking abilities than people with lower amounts of protein from the gene called brain-derived neurotrophic factor, or BDNF, according to a study published in the January 27, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
New findings offer roadmap for development of novel therapies to target common brain disorders

New findings offer roadmap for development of novel therapies to target common brain disorders

Scientists have pinpointed the cells that are likely to trigger common brain disorders, including Alzheimer's disease, Multiple Sclerosis and intellectual disabilities. [More]

Lilly, Roche Diagnostics partner to develop cerebrospinal fluid assay for amyloid-beta 1-42

Eli Lilly and Company today announced an arrangement to partner with Roche Diagnostics on its ongoing development of a commercially scalable cerebrospinal fluid assay for amyloid-beta 1-42. [More]
Patients who receive information about coronary artery disease risk make improvements to health behaviors

Patients who receive information about coronary artery disease risk make improvements to health behaviors

A new study led by researchers at Brigham and Women's Hospital has found that providing unanticipated information about risk of coronary artery disease during a genetic risk assessment for Alzheimer's disease helped some participants cope with their results, and also motivated participants to make changes to their health behaviors. [More]
Synaptic plasticity alterations responsible for memory impairment in Alzheimer's disease

Synaptic plasticity alterations responsible for memory impairment in Alzheimer's disease

Neurons communicate with one another by synaptic connections, where information is exchanged from one neuron to its neighbor. These connections are not static, but are continuously modulated in response to the ongoing activity (or experience) of the neuron. This process, known as synaptic plasticity, is a fundamental mechanism for learning and memory in humans as in all animals. [More]
Genes that influence people's health also have impact on some cognitive functions

Genes that influence people's health also have impact on some cognitive functions

Genes that influence people's health also shape how effectively they think, a study shows. Scientists found that genes associated with diseases including Alzheimer's disease, schizophrenia, and autism also have an impact on some cognitive functions. [More]
Preventing memory loss in Alzheimer's Disease, a new key mechanism

Preventing memory loss in Alzheimer's Disease, a new key mechanism

Neurons communicate with one another by synaptic connections, where information is exchanged from one neuron to its neighbor. These connections are not static, but are continuously modulated in response to the ongoing activity (or experience) of the neuron. [More]
Chronic exposure to environmental toxin may up risk of neurodegenerative illness

Chronic exposure to environmental toxin may up risk of neurodegenerative illness

A new study published today in the science journal Proceedings of the Royal Society B indicates that chronic exposure to an environmental toxin may increase risk of neurodegenerative illness. Conducted by scientists at the Institute for EthnoMedicine, a non-profit medical research organization, and the University of Miami Brain Endowment Bank, the study provides a foundation for future research in Alzheimer's disease, ALS and Parkinson's disease. [More]
Oestrogen supplements could reduce dementia risk in women

Oestrogen supplements could reduce dementia risk in women

Women who take oestrogen supplements from before or at the start of menopause and continue with them for a few years have better preserved brain structure, which may reduce the risk of dementia. [More]
People suffering from chronic stress, anxiety may be at increased risk for depression and dementia

People suffering from chronic stress, anxiety may be at increased risk for depression and dementia

A scientific review paper warns that people need to find ways to reduce chronic stress and anxiety in their lives or they may be at increased risk for developing depression and even dementia. [More]
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