Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Scientists develop an mRNA technology approach to target Alzheimer’s disease

Scientists at The Florey have developed an mRNA technology approach to target the toxic protein tau, which builds up in patients with Alzheimer's disease and other dementias.

28 Mar 2024

Genetic and lifestyle factors linked to brain network aging, study reveals

Research highlights the impact of genetic and lifestyle factors on a brain network particularly sensitive to aging, schizophrenia, and Alzheimer's disease, using data from nearly 40,000 UK Biobank participants to investigate modifiable risk factors and genetic associations.

28 Mar 2024

Dietary vitamin A shows promise in Alzheimer's disease intervention, study finds

Study explored the impact of dietary vitamin A on gut microbiota and intestinal transcriptome, revealing its potential in Alzheimer's disease (AD) pathology and cognitive functions in mice.

28 Mar 2024

Familial Alzheimer's transmissible through bone marrow transplants, study shows

Familial Alzheimer's disease can be transferred via bone marrow transplant, researchers show March 28 in the journal Stem Cell Reports.

28 Mar 2024

New imaging technique maps oxygen movement in the brain

The human brain consumes vast amounts of energy, which is almost exclusively generated from a form of metabolism that requires oxygen.

28 Mar 2024

Mobile memory tests offer new hope for Alzheimer's detection

Dedicated memory tests on smartphones enable the detection of "mild cognitive impairment", a condition that may indicate Alzheimer's disease, with high accuracy.

27 Mar 2024

Study reveals risk factors for faster aging in the brain

The researchers had previously identified a 'weak spot' in the brain, which is a specific network of higher-order regions that not only develop later during adolescence, but also show earlier degeneration in old age.

27 Mar 2024

Xenotransplantation model used for studying microglial response to Alzheimer's disease

Microglia are specialized immune cells in the brain. While they normally protect our brains, they can also contribute to neurodegenerative diseases such as Alzheimer's.

27 Mar 2024

Multiomic approach boosts disease prediction accuracy beyond traditional methods

Study highlights the significant enhancement in predicting common diseases like heart disease, diabetes, Alzheimer's, and prostate cancer by integrating polygenic risk scores (PRSs) and gut microbiome scores with conventional risk factors, showcasing the potential of multiomic approaches in personalized medicine.

26 Mar 2024

Study identifies brain energy metabolism dysfunction in neuropsychiatric disorders

A global collaborative research group comprising 131 researchers from 105 laboratories across seven countries announces a groundbreaking research paper submitted to eLife.

26 Mar 2024

Researchers identify new potential target for the treatment of Alzheimer's disease

Researchers at the University of Leeds and Lancaster University in the UK have identified a new potential target for the treatment of Alzheimer's disease – PDE4B.

26 Mar 2024

Mediterranean diet linked to lower dementia risk, finds extensive review

Meta-analysis reveals a positive link between adherence to the Mediterranean diet and a reduced risk of dementia, particularly Alzheimer's disease, among older adults, highlighting the diet's potential as a modifiable risk factor in dementia prevention strategies.

26 Mar 2024

Study adds new evidence on the link between Type 2 diabetes and Alzheimer's disease

New research conducted in mice offers insights into what's going on at the molecular level that could cause people with diabetes to develop Alzheimer's disease.

25 Mar 2024

Reciprocated care in Alzheimer's couples enhances mutual well-being

In cases of Alzheimer's disease, it's common for a spouse to take on the role of caregiver. Research led by the University of California, Davis, suggests that patients can also support their caretakers, and that reciprocated care has mutual benefits.

22 Mar 2024

New drug inhibitors target protein linked to Alzheimer's and heart disease

The health impacts of a complex protein that plays a major role in the development of Alzheimer's disease and heart conditions can be lessened by three kinds of drug inhibitors, according to scientists at the University of Colorado Anschutz Medical Campus.

22 Mar 2024

Study shows cellular, molecular overlaps in ALS and FTLD

On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies frontotemporal dementia, manifest in very different ways. In addition, they are known to primarily affect very different regions of the brain.

22 Mar 2024

Aging linked to length of genes, study suggests

Aging may be less about specific "aging genes" and more about how long a gene is. Many of the changes associated with aging could be occurring due to decreased expression of long genes, say researchers in an opinion piece publishing March 21 in the journal Trends in Genetics.

22 Mar 2024

Long genes linked to faster biological aging

What causes our body to age? Four complementary studies, including one from Northwestern Medicine, have come to the same conclusion: long genes.

21 Mar 2024

Scientists shed light on key immune regulators involved in Alzheimer’s and other disorders of lipid-rich tissues

Using novel genetic and genomic tools, researchers at the Icahn School of Medicine at Mount Sinai have shed light on the role of immune cells called macrophages in lipid-rich tissues like the brain, advancing our understanding of Alzheimer's and other diseases.

21 Mar 2024

Study pinpoints several genetic variants contributing to Alzheimer's disease

Identifying genetic variants and the role they play in predisposing people to Alzheimer's disease can help researchers better understand how to treat the neurodegenerative condition for which there is currently no cure.

21 Mar 2024