Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Better cardiovascular health among middle-aged Black women linked to less decline in cognition

Better heart health was linked to less decline in mental processing speed and cognition among middle-aged Black women, although not among middle-aged white women, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

24 Apr 2024

Neurons re-entering cell cycle succumb to senescence in neurodegenerative diseases

Post-mitotic neurons in the brain that re-enter the cell cycle quickly succumb to senescence, and this re-entry is more common in Alzheimer's disease, according to a new study published April 9th in the open-access journal PLOS Biology by Kim Hai-Man Chow and colleagues at the Chinese University of Hong Kong.

23 Apr 2024

$4.8 million grant supports research on TDP-43 misfolding in neurodegenerative diseases

A new $4.8 million grant will support researchers from Indiana University School of Medicine and the Medical Research Council Laboratory of Molecular Biology to study how human neurodegenerative diseases are affected by the misfolding of the protein TDP-43.

23 Apr 2024

Bursts of beta rhythms control cognition in the brain

The brain processes information on many scales. Individual cells electrochemically transmit signals in circuits but at the large scale required to produce cognition, millions of cells act in concert, driven by rhythmic signals at varying frequencies.

23 Apr 2024

State-of-the art imaging reveals how lipid metabolism is changed in Alzheimer's disease

Alzheimer's disease causes significant problems with memory, thinking and behavior and is the most common form of dementia, affecting more than 50 million people around the world each year.

23 Apr 2024

New tool hunts for Alzheimer's clues in gut microbiome

Cleveland Clinic researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease.

23 Apr 2024

Large-scale study identifies new approach to early Alzheimer's detection

Digital memory test and a blood sample - this combination will be tested for its potential to identify early Alzheimer's disease in a new research study. Over a hundred healthcare centers are part of the study that is now inviting participants to sign up. At least 3,000, preferably many more participants are needed for the study to be successful.

23 Apr 2024

Study identifies potential strategy to diminish the devastating impacts of traumatic brain injuries

For the roughly 1.5 million Americans per year who survive a traumatic brain injury, health outcomes vary widely.

22 Apr 2024

New platform can deliver gene therapy precisely to specific areas of the brain

A novel approach to gene therapy is improving lives in ways once thought impossible. Researchers at The Ohio State University Wexner Medical Center and College of Medicine have developed a new platform to deliver the gene therapy precisely to specific areas of the brain.

18 Apr 2024

Exploring the benefits of blueberries: Studies link extract to reduced cognitive aging

Wild blueberry extracts (WBE) may improve cognitive performance.

18 Apr 2024

Salk scientists explain how CBN protects the brain against aging and neurodegeneration

One in every 10 individuals above the age of 65 develops an age-related neurological disorder like Alzheimer's or Parkinson's, yet treatment options remain sparse for this population.

17 Apr 2024

Universities collaborate on $15 million project investigating inflammation's role in cardiac and brain diseases

Research teams from Northwestern University Chicago Campus, University of Michigan and University of Pittsburgh will lead a $15 million project dedicated to studying inflammation's role in cardiac and brain diseases.

17 Apr 2024

Study reveals neuronal mechanisms behind working memory

Cedars-Sinai investigators have discovered how brain cells responsible for working memory-;the type required to remember a phone number long enough to dial it-;coordinate intentional focus and short-term storage of information.

17 Apr 2024

Vaccines targeting chronic diseases show promise in combatting age-related conditions

Vaccine-based therapeutics for age-related disorders.

17 Apr 2024

Study reveals accelerated progression of Alzheimer's in people with Down syndrome

Nearly all adults with Down syndrome will develop evidence of Alzheimer's disease by late middle age.

16 Apr 2024

Junk food-filled diet in teens may disrupt brains' memory ability for a long time

A new USC-led study on rats that feasted on a high-fat, sugary diet raises the possibility that a junk food-filled diet in teens may disrupt their brains' memory ability for a long time.

16 Apr 2024

Common HIV drugs linked to reduced Alzheimer's disease risk

Alzheimer's disease (AD) currently afflicts nearly seven million people in the U.S. With this number expected to grow to nearly 13 million by 2050, the lack of meaningful therapies represents a major unmet medical need.

16 Apr 2024

Study unlocks genetic secrets in APOEε4 carriers that could defend against Alzheimer's

Researchers utilized whole-genome sequencing and pathway analysis to uncover protective genetic variations against Alzheimer's disease in APOEε4 carriers, revealing a crucial role for extracellular matrix-related genes in mitigating the disease's progression.

15 Apr 2024

Mayo Clinic study offers insights into lucid episodes in dementia

A recent Mayo Clinic study published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association investigated lucid episodes in people living with later stages of dementia, providing insights into how these occurrences reveal themselves.

13 Apr 2024

Geraniol alleviates cognitive decline in D-galactose-induced aging mice

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 6, entitled, "Geraniol attenuates oxidative stress and neuroinflammation-mediated cognitive impairment in D galactose-induced mouse aging model."

12 Apr 2024

Alzheimer's Disease News and Research

Further Reading

Better cardiovascular health among middle-aged Black women linked to less decline in cognition

Neurons re-entering cell cycle succumb to senescence in neurodegenerative diseases

$4.8 million grant supports research on TDP-43 misfolding in neurodegenerative diseases

Bursts of beta rhythms control cognition in the brain

State-of-the art imaging reveals how lipid metabolism is changed in Alzheimer's disease

New tool hunts for Alzheimer's clues in gut microbiome

Large-scale study identifies new approach to early Alzheimer's detection

Study identifies potential strategy to diminish the devastating impacts of traumatic brain injuries

New platform can deliver gene therapy precisely to specific areas of the brain

Exploring the benefits of blueberries: Studies link extract to reduced cognitive aging

Salk scientists explain how CBN protects the brain against aging and neurodegeneration

Universities collaborate on $15 million project investigating inflammation's role in cardiac and brain diseases

Study reveals neuronal mechanisms behind working memory

Vaccines targeting chronic diseases show promise in combatting age-related conditions

Study reveals accelerated progression of Alzheimer's in people with Down syndrome

Junk food-filled diet in teens may disrupt brains' memory ability for a long time

Common HIV drugs linked to reduced Alzheimer's disease risk

Study unlocks genetic secrets in APOEε4 carriers that could defend against Alzheimer's

Mayo Clinic study offers insights into lucid episodes in dementia

Geraniol alleviates cognitive decline in D-galactose-induced aging mice

Aneuro: A Year of Neuroscience in Review eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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