Researchers at USC have found that a class of pharmaceuticals can both prevent and treat Alzheimer's Disease in mice.
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While Huntington's disease (HD) is currently incurable, the HD research community anticipates that new disease-modifying therapies in development may slow or minimize disease progression. The success of HD research depends upon the identification of reliable and sensitive biomarkers to track disease and evaluate therapies, and these biomarkers may eventually be used as outcome measures in clinical trials. Biomarkers could be especially helpful to monitor changes during the time prior to diagnosis and appearance of overt symptomatology.
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Researchers have pinpointed a catalytic trigger for the onset of Alzheimer's disease - when the fundamental structure of a protein molecule changes to cause a chain reaction that leads to the death of neurons in the brain.
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Television actor and "Dancing with the Stars" winner John O'Hurley is the host of Epilepsy: A Guide for Patients and Families, the latest free patient education DVD and guidebook produced by the American Academy of Neurology and its foundation, the American Brain Foundation.
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Non-invasive brain stimulation techniques aimed at mental and neurological conditions include transcranial magnetic stimulation for depression, and transcranial direct current (electrical) stimulation, shown to improve memory.
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Treatment for alcohol use disorders works best if the patient actively understands and incorporates the interventions provided in the clinic.
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Scientists investigating the interaction of a group of proteins in the brain responsible for protecting nerve cells from damage have identified a new target that could increase cell survival.
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Insero Health, Inc., a company developing natural compounds to address unmet medical needs in epilepsy and related neurological disorders, is today reporting top-line results from a Phase Ib trial of its lead compound INS001 in patients with drug-resistant epilepsy.
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Political and ethical fights over human cloning may follow the latest stem cell therapy advance after scientists created embryos that are genetic copies of living people in an effort to treat diseases such as Alzheimer's.
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People who have skin cancer may be less likely to develop Alzheimer's disease, according to new research published in the May 15, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology. The link does not apply to melanoma, a less common but more aggressive type of skin cancer.
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When the brain's primary "learning center" is damaged, complex new neural circuits arise to compensate for the lost function, say life scientists from UCLA and Australia who have pinpointed the regions of the brain involved in creating those alternate pathways - often far from the damaged site.
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Today's headlines detail the Senate confirmation of Acting Chief Marilyn Tavenner to run the Centers for Medicare & Medicaid Services.
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The red double-decker buses that are symbolic of the city of London have an altogether different significance if you study heart disease. Sixty years ago, these iconic buses helped a Scottish medical doctor named Jerry Morris discover the link between physical activity and heart attacks.
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Scientists at Washington University School of Medicine in St. Louis have helped identify many of the biomarkers for Alzheimer's disease that could potentially predict which patients will develop the disorder later in life.
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Forget apples - lifting weights and doing cardio can also keep the doctors away, according a new study by researchers at the University of British Columbia and Vancouver Coastal Health Research Institute.
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Once famously described as "orphan diseases, too small to be noticed, too small to be funded" in the Hollywood drama Lorenzo's Oil, rare diseases are getting unprecedented attention today among drug manufacturers, who are ramping up research efforts and marketing new medicines that promise fuller lives for children and other patients with these heartbreaking conditions.
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A drug developed by scientists at the Salk Institute for Biological Studies, known as J147, reverses memory deficits and slows Alzheimer's disease in aged mice following short-term treatment.
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Researchers at Georgetown University Medical Center have used tiny doses of a leukemia drug to halt accumulation of toxic proteins linked to Parkinson's disease in the brains of mice. This finding provides the basis to plan a clinical trial in humans to study the effects.
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When his wife got Alzheimer's disease, lawyer Ken Chiate invested all his hopes in an unorthodox treatment. Nothing, it seems, could make him give up on it. ... Jeannette's difficulties seemed to emerge out of nowhere. She couldn't grasp the rules of a dice game. She kept asking questions her husband had just answered. ... in 2001, at age 58, she was diagnosed with mild cognitive impairment. As months and years passed, she fell into an angry haze that was determined to be Alzheimer's disease.
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In many neurodegenerative diseases the neurons of the brain are over-stimulated and this leads to their destruction. After many failed attempts and much scepticism this process was finally shown last year to be a possible basis for treatment in some patients with stroke. But very few targets for drugs to block this process are known.
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