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Amino Acid is one of several molecules that join together to form proteins. There are 20 common amino acids found in proteins.
Brazilian study discovers promising therapeutic and diagnostic target for treatment of melanoma

Brazilian study discovers promising therapeutic and diagnostic target for treatment of melanoma

A Brazilian study shows that inhibition of an RNA named RMEL3, which is encoded by a previously uncharacterized gene (also named RMEL3), can reduce the viability of cultured melanoma cells by up to 95%. [More]
Iron-containing catalysts can alter amino acids to help develop new drug candidates

Iron-containing catalysts can alter amino acids to help develop new drug candidates

For medicinal chemists, making tweaks to peptide structures is key to developing new drug candidates. Now, researchers have demonstrated that two iron-containing small-molecule catalysts can help turn certain types of amino acids -- the building blocks of peptides and proteins -- into an array of potential new forms, even when part of a larger peptide, while preserving a crucial aspect of their chemistry: chirality, or "handedness." [More]
Researchers identify biomarkers to improve prognosis of CKD

Researchers identify biomarkers to improve prognosis of CKD

Currently, there is no effective method to predict the prognosis of chronic kidney disease (CKD) patients. [More]
Researchers discover pathway linking oxidative stress and cysteine in Huntington's disease

Researchers discover pathway linking oxidative stress and cysteine in Huntington's disease

Researchers at Johns Hopkins Medicine report they have identified a biochemical pathway linking oxidative stress and the amino acid cysteine in Huntington's disease. [More]
Scientists design and construct 10 large protein icosahedra to improve drug delivery

Scientists design and construct 10 large protein icosahedra to improve drug delivery

Using novel computational and biochemical approaches, scientists have accurately designed and built from scratch 10 large protein icosahedra--polyhedra with 20 faces--similar to viral capsids that carry viral DNA. [More]
Researchers identify unique mechanism to suppress colorectal cancer tumors in mice

Researchers identify unique mechanism to suppress colorectal cancer tumors in mice

A new scientific study has identified why colorectal cancer cells depend on a specific nutrient, and a way to starve them of it. Over one million men and women are living with colorectal cancer in the United States. [More]
Researchers discover how Zika virus travels from pregnant mother to fetus

Researchers discover how Zika virus travels from pregnant mother to fetus

Zika virus can infect numerous cell types in the human placenta and amniotic sac, according to researchers at UC San Francisco and UC Berkeley who show in a new paper how the virus travels from a pregnant woman to her fetus. They also identify a drug that may be able to block it. [More]
Scientists capture atomic level snapshots of how key enzyme modifies signaling proteins

Scientists capture atomic level snapshots of how key enzyme modifies signaling proteins

Scientists have captured atomic level snapshots showing how one key enzyme modifies a protein involved in turning genes on or off inside cells. Understanding this process-which is particularly important when cells are first taking on specialized identities such as nerve cells, muscle, skin, and so on-helps explain how complex organisms can arise from a finite number of genes. [More]
Biochemists design genetic poison pill to thwart coxsackievirus B3

Biochemists design genetic poison pill to thwart coxsackievirus B3

It has a funny name - coxsackievirus - but there's nothing funny about how this tiny germ and its close relatives sicken their hosts. [More]
Scientists discover key 'twist' in Rubik's cube-like plant puzzle

Scientists discover key 'twist' in Rubik's cube-like plant puzzle

Scientists at the John Innes Centre have discovered a key "twist" in a Rubik's cube-like plant puzzle, which could pave the way to new, or more effective pharmaceuticals. [More]
Researches create mini-brain model of idiopathic ASD characterized by early neuronal overgrowth

Researches create mini-brain model of idiopathic ASD characterized by early neuronal overgrowth

The vast majority of cases of autism spectrum disorder (ASD) are idiopathic - the cause is unknown. [More]
Researchers reveal how bacterial cell wall adapts to threatening environments

Researchers reveal how bacterial cell wall adapts to threatening environments

Researchers at Umea University in Sweden have published new findings on the adaptation of the bacterial cell wall in the Journal of the American Chemical Society. [More]
Diabetes drug metformin could help reduce toxic acid levels linked to MSUD

Diabetes drug metformin could help reduce toxic acid levels linked to MSUD

Maple Syrup Urine Disease (MSUD) is a rare inherited metabolic disorder involving the dysfunction of an enzyme which breaks down three essential amino acids: leucine, isoleucine and valine. [More]
New research holds potential to improve fetal surgery outcomes

New research holds potential to improve fetal surgery outcomes

University of California, Berkeley engineer Phillip Messersmith is happy to be learning lessons from a lowly mollusk, with the expectation that the knowledge gained will enable him and fellow physicians to prevent deaths among their youngest patients -- those who haven't been born yet. [More]
AHR plays role in modulating the body's innate immune response to viral infections

AHR plays role in modulating the body's innate immune response to viral infections

A receptor, first known for its role in mediating the harmful effects of the environmental pollutant dioxin in our body, is now understood to play other important roles in modulating the innate immune response. [More]
Using NMR to investigate intrinsically disordered proteins: an interview with Dr Isabella Felli

Using NMR to investigate intrinsically disordered proteins: an interview with Dr Isabella Felli

“IDPs” is now a widely used acronym that stands for “intrinsically disordered proteins.” It is the term generally used by the scientific community to refer to a wide variety of proteins that do not have a stable 3D structure and are instead characterized by a high extent of local mobility, disorder and many conformers that are accessible at room temperature. [More]
Scientists uncover how changes in metabolism of embryonic stem cells can help engineer new blood vessels

Scientists uncover how changes in metabolism of embryonic stem cells can help engineer new blood vessels

Researchers from the University of Illinois at Chicago College of Medicine have uncovered how changes in metabolism of human embryonic stem cells help coax them to mature into specific cell types — and may improve their function in engineered organs or tissues. [More]
Mayo researchers develop extremely precise assay to measure age-associated changes in GDF11

Mayo researchers develop extremely precise assay to measure age-associated changes in GDF11

Researchers at Mayo Clinic have developed an accurate way to measure a circulating factor, called GDF11, to better understand its potential impact on the aging process. [More]
Researchers reveal how cancer cells use energy to move and divide so quickly

Researchers reveal how cancer cells use energy to move and divide so quickly

Cancer cells and normal cells both divide and move, but with cancer cells it's like they're on steroids: everything is bigger, faster, more. [More]
New study may help unveil structure and behavior of neurotoxic oligomers in Alzheimer's disease

New study may help unveil structure and behavior of neurotoxic oligomers in Alzheimer's disease

Much of the research on Alzheimer's disease has focused on the amyloid beta protein, which clumps together into sticky fibrils that form deposits in the brains of people with the disease. [More]
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