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Medication use and doctor visits drive up jaw necrosis-related costs

Medication use and doctor visits drive up jaw necrosis-related costs

Long-term medication use and follow-up visits are the main drivers affecting costs associated with cancer-related bisphosphonate-associated osteonecrosis of the jaw, report researchers in Oral Diseases. [More]
Amoxicillin effectiveness: an interview with Prof Paul Little, University of Southampton

Amoxicillin effectiveness: an interview with Prof Paul Little, University of Southampton

Amoxicillin is a broad spectrum penicillin, and in the UK is one of the most frequently used antibiotics. It is commonly used either on its own or, where there are particular concerns about resistance, in combination as Co-amoxiclav (as Amoxicillin-clavulanic acid) which extends its anti-bacterial spectrum. [More]
Antibiotics help severely malnourished children recover

Antibiotics help severely malnourished children recover

Giving severely malnourished children antibiotics in addition to nutritional therapy significantly improves their chances of making a full recovery compared with nutritional therapy alone, say researchers. [More]
Two new studies examine causes, treatment of severe malnutrition

Two new studies examine causes, treatment of severe malnutrition

"Two studies of malnourished children offer the first major new scientific findings in a decade about the causes and treatment of severe malnutrition, which affects more than 20 million children around the world and contributes to the deaths of more than a million a year," the New York Times reports. [More]
Emerging tick-borne disease reaches USA

Emerging tick-borne disease reaches USA

A new tick-borne infection caused by the spirochete bacteria Borrelia miyamotoi that produces similar symptoms to Lyme disease has been confirmed in a small number of patients in the USA. [More]
Study highlights the need for more targeted antibiotic therapy in cancer patients

Study highlights the need for more targeted antibiotic therapy in cancer patients

What cancerous conditions lead to what kinds of bacterial infections? If doctors knew, they could predict which patients would likely benefit from pre-treatment with certain kinds of antibiotics. [More]
Antibiotics do not help lower-respiratory tract infections

Antibiotics do not help lower-respiratory tract infections

The antibiotic amoxicillin fares no better at reducing symptoms in patients with lower-respiratory tract infections than a placebo drug, indicate data from a dozen European countries. [More]
Antibiotic amoxicillin ineffective for treating cough according to European trial

Antibiotic amoxicillin ineffective for treating cough according to European trial

The antibiotic amoxicillin, that doctors typically prescribe for common lower respiratory tract infections (LRTI) such as cough and bronchitis, is no more effective at relieving symptoms than the use of no medication, even in older patients. The findings from the largest randomised placebo controlled trial of antibiotics for acute uncomplicated LRTI to date are published Online First in The Lancet Infectious Diseases. [More]
Strep throat should be treated with penicillin or amoxicillin: IDSA guidelines

Strep throat should be treated with penicillin or amoxicillin: IDSA guidelines

Although people often say they have "strep" throat, most sore throats actually are caused by a virus, not streptococcus bacteria, and shouldn't be treated with antibiotics, suggest guidelines published by the Infectious Diseases Society of America (IDSA). Antibiotics are ineffective against viruses. [More]

Antibiotic treatment more effective than placebo in patients with mild-to-moderate COPD

Antibiotic treatment with amoxicillin/clavulanate improves moderate exacerbations in patients with mild-to-moderate chronic obstructive pulmonary disease (COPD) and significantly prolongs the time between exacerbations, according to a new study from researchers in Spain. [More]
Family members of children with staph infections often harbor drug-resistant germs

Family members of children with staph infections often harbor drug-resistant germs

Family members of children with a staph infection often harbor a drug-resistant form of the germ, although they don't show symptoms, a team of researchers from Washington University School of Medicine in St. Louis has found. [More]
U.N. SG Ban praises commission on life-saving commodities, says more effort needed to improve maternal, child mortality rates

U.N. SG Ban praises commission on life-saving commodities, says more effort needed to improve maternal, child mortality rates

At the opening of the U.N. Commission on Life-Saving Commodities for Women and Children on Tuesday, U.N. Secretary-General Ban Ki-moon praised the commission but "said that much remains to be done to save the lives of the 800 women and more than 20,000 children who die every day from preventable causes," the U.N. News Centre reports. [More]
Pernix Therapeutics introduces Omeclamox-Pak® for the treatment of H. pylori infection and duodenal ulcer disease

Pernix Therapeutics introduces Omeclamox-Pak® for the treatment of H. pylori infection and duodenal ulcer disease

Pernix Therapeutics Holdings, Inc. (NYSE Amex: PTX), a specialty pharmaceutical company, today announced the introduction of Omeclamox-PakĀ®, a ten-day therapy of omeprazole delayed-release capsules (20 mg), clarithromycin tablets (500 mg) and amoxicillin capsules (500 mg) for the treatment of Helicobacter pylori (H. pylori) infection and duodenal ulcer disease (active or one-year history) to eradicate H. pylori in adult patients. [More]

Ciprofloxacin, TMP-SMX no longer safe for outpatient urinary tract infection

In a surveillance study of over 12 million bacteria, investigators at The George Washington University and Providence Hospital found E. coli antimicrobial resistance to ciprofloxacin, the most commonly prescribed antimicrobial for urinary tract infections in the U.S., increased over five-fold from 2000 to 2010. [More]
Amoxicillin-clavulanate may improve small bowel function in children experiencing motility disturbances

Amoxicillin-clavulanate may improve small bowel function in children experiencing motility disturbances

The common antibiotic, amoxicillin-clavulanate, may improve small bowel function in children experiencing motility disturbances, according to a study appearing in the June print edition of the Journal of Pediatric Gastroenterology and Nutrition from Nationwide Children's Hospital. [More]
IDSA releases new rhinosinusitis guidelines

IDSA releases new rhinosinusitis guidelines

The vast majority of sinus infections are caused by viruses and should not be treated with antibiotics, suggest new guidelines released by the Infectious Diseases Society of America. [More]

Amoxicillin not effective for patients with acute rhinosinusitis

Treatment with the antibiotic amoxicillin for patients with acute uncomplicated rhinosinusitis (inflammation of the nasal cavity and sinuses) did not result in a significant difference in symptoms compared to patients who received placebo, according to a study in the February 15 issue of JAMA. Antibiotics are commonly used to treat this condition even though there is limited evidence supporting their effectiveness. [More]

Antibiotic prescriptions do not reduce sinus symptoms

Antibiotics that doctors typically prescribe for sinus infections do not reduce symptoms any better than an inactive placebo, according to investigators at Washington University School of Medicine in St. Louis. [More]
Three Johns Hopkins scientists receive NIH Director's New Innovator Awards

Three Johns Hopkins scientists receive NIH Director's New Innovator Awards

A pioneer in the field of epigenetics who has been spearheading the use of genome-wide technology for epigenetics research, a researcher who has revealed a weakness in the tuberculosis bacterium that makes it more susceptible to antibiotics, and a scientist who seeks to revolutionize new methods for toxicological testing to improve human health and reduce animal testing have received Director's Awards from the National Institutes of Health. [More]
New IDSA/PIDS guidelines can thwart pneumonia in children

New IDSA/PIDS guidelines can thwart pneumonia in children

Immunizations, including a yearly flu vaccine, are the best way to protect children from life-threatening pneumonia, according to new guidelines from the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America. [More]