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Highland completes US$25 million offering of Class A Common Shares

Highland completes US$25 million offering of Class A Common Shares

Highland Therapeutics Inc., a pharmaceutical company, today announced it has completed a US$25 million offering of Class A Common Shares. The financing was led by a private equity partner that is committed to Highland's long-term success. [More]
Shire receives FDA guidance on regulatory path for investigational compound SHP 465

Shire receives FDA guidance on regulatory path for investigational compound SHP 465

Shire plc today announced that it has received further guidance from the U.S. Food and Drug Administration on the regulatory path for SHP 465 (triple-bead mixed amphetamine salts MAS), an investigational oral stimulant medication being evaluated as a potential treatment for Attention-Deficit/Hyperactivity Disorder (ADHD) in adults. [More]
AMRI total revenue increases 15% to $68.2 million in second quarter 2014

AMRI total revenue increases 15% to $68.2 million in second quarter 2014

AMRI today reported financial and operating results for the second quarter ended June 30, 2014. [More]
Study explores how changes in dopamine transporter function linked to brain disorders

Study explores how changes in dopamine transporter function linked to brain disorders

Recent published research in the Journal of Clinical Investigation demonstrates how changes in dopamine signaling and dopamine transporter function are linked to neurological and psychiatric diseases, including early-onset Parkinsonism and attention deficit hyperactivity disorder (ADHD). [More]
Researchers identify genetic mutation that may cause parkinsonism in young people

Researchers identify genetic mutation that may cause parkinsonism in young people

Researchers at the University of Copenhagen and the Copenhagen University Hospital have identified a particular genetic mutation that may cause parkinsonism in young people. The mutation interferes with the brain's transport of the important signal substance dopamine and may also plays a role in mental diseases, e.g. ADHD. [More]
Study shows amphetamines can keep exhaustion at bay in male rats

Study shows amphetamines can keep exhaustion at bay in male rats

Indiana University researchers put male rats to the test to determine the role amphetamines play when used in conjunction with exercise. [More]
Neurovance reports positive results from EB-1020 SR phase 2a pilot study in adult ADHD patients

Neurovance reports positive results from EB-1020 SR phase 2a pilot study in adult ADHD patients

Neurovance, Inc. today announced complete results from its phase 2a pilot study of EB-1020 SR, a non-stimulant, in adult male patients with all subtypes of ADHD (attention deficit hyperactivity disorder). [More]

Highland subsidiary begins enrolment in Phase III study of HLD-200 in pediatric ADHD patients

Highland Therapeutics Inc., an emerging pharmaceutical company, today announced that its wholly owned subsidiary has begun enrolment in a Phase III study of HLD-200, the Company's novel formulation of methylphenidate, in pediatric patients with Attention-Deficit Hyperactivity Disorder ("ADHD"). [More]
Neurovance closes $6.3M extension to its series A1 financing round to advance development of EB-1020 SR

Neurovance closes $6.3M extension to its series A1 financing round to advance development of EB-1020 SR

Neurovance, Inc. today announced that it has closed a $6.3 million extension to its series A1 financing round to further advance development of EB-1020 SR, a non-stimulant, for the treatment of all subtypes of adult ADHD (attention deficit hyperactivity disorder). [More]
Chemists able to trace narcotics substances, prescription drugs in Swedish wastewater

Chemists able to trace narcotics substances, prescription drugs in Swedish wastewater

Chemists at Ume- University in Sweden have been able to trace narcotics substances and prescription drugs in measurements of wastewater from 33 Swedish sewage treatment plants. Cocaine, amphetamine, and methamphetamine, in measurable concentrations, were found in a total of half of the locations. [More]

Research highlights value of fathers in both neurobiology and behavior of offspring

Even with today's technology, it still takes both a male and a female to make a baby. But is it important for both parents to raise that child? Many studies have outlined the value of a mother, but few have clearly defined the importance of a father, until now. [More]

High doses of ADHD drugs may be effective for people with amphetamine dependency

People with ADHD and dependency rarely respond as they should to ADHD drugs. A randomised study from Karolinska Institutet in Sweden now shows that it is possible to obtain the desired efficacy by administering the drug in higher doses. [More]
Study proposes novel treatment for narcolepsy

Study proposes novel treatment for narcolepsy

Lancet Neurology, a prestigious journal in its domain, publishes in its last issue, an article entitled "Pitolisant versus placebo and modafinil in patients with narcolepsy: a double-blind randomised trial" authored by Y. Dauvilliers and others from the HARMONY I study group which proposes a novel treatment for this orphan disease. It is accompanied by a Commentary entitled "A need for new treatments in narcolepsy". [More]
Study looks at attitudes toward drug use among high school seniors

Study looks at attitudes toward drug use among high school seniors

High school seniors who frown upon the use of drugs are most likely to be female, nonsmokers or hold strong religious beliefs, according to a study- by Joseph Palamar of New York University. Palamar examines how teenagers' attitudes toward marijuana influenced their thoughts on the further use of other illicit drugs. [More]
ERK pathway discovery may provide therapeutic options for treating drug addictions

ERK pathway discovery may provide therapeutic options for treating drug addictions

The extracellular-signal regulated kinase (ERK) pathway plays a role in multiple drug addictions and appears to modulate neuronal plasticity through epigenetic mechanisms, say French scientists. [More]

New website aims to reduce negative impact of amphetamine use

Reducing the negative impact of amphetamine use is the aim of a new website launched by a Griffith University PhD candidate, in the face of this significant drug problem. [More]
Caffeine-laden energy drinks pose hazards to adolescents

Caffeine-laden energy drinks pose hazards to adolescents

Parents beware. If your tots and teens get their hands on your energy drinks, they could experience seizures, heart palpitations or other problems that drive them to the hospital emergency room. [More]
Opioid dependence causes greatest health burden of all illicit drugs

Opioid dependence causes greatest health burden of all illicit drugs

The first ever analysis of the global and regional prevalence of dependence upon the four major categories of illicit drugs – amphetamine, cannabis, cocaine, and opioids (such as heroin) – has revealed that opioid dependence causes the greatest health burden (overall death and illness) of all the illicit drugs. The results come from new analysis of the Global Burden of Disease Study 2010, and are published in The Lancet. [More]
Scientists report possible basis for why food-restricted animals show susceptibility to drugs of abuse

Scientists report possible basis for why food-restricted animals show susceptibility to drugs of abuse

Scientists today reported a possible basis for why food-restricted animals show increased susceptibility to drugs of abuse. This association has puzzled researchers since it was first observed more than three decades ago. [More]
Study finds that long-term cannabis use affects motivation

Study finds that long-term cannabis use affects motivation

Long-term cannabis users tend to produce less dopamine, a chemical in the brain linked to motivation, a study has found. [More]