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Anal cancer is a type of cancer which arises from the anus, the distal orifice of the gastrointestinal tract. It is a distinct entity from the more common colorectal cancer.

Cleveland Clinic receives $2M for research in colorectal surgery

Kenneth M. Garschina and his wife, Sara Story, have pledged $2 million to Cleveland Clinic's Digestive Disease Institute to create an endowed chair for research in colorectal surgery. The donation coincides with the re-dedication of two previously funded endowed chairs. [More]
Advaxis completes ADXS-HPV Phase 1/2 dosing in patients with HPV-associated anal cancer

Advaxis completes ADXS-HPV Phase 1/2 dosing in patients with HPV-associated anal cancer

Advaxis, Inc., a leader in developing the next generation of immunotherapies for cancer and infectious diseases, announced that the first patient has been dosed in a Phase 1/2 study of ADXS-HPV in 25 patients with HPV-associated anal cancer coordinated by the Brown University Oncology Research Group (BrUOG). [More]
Advaxis to license its ADXS-HPV product candidate to FusionVax

Advaxis to license its ADXS-HPV product candidate to FusionVax

Advaxis, Inc., a leader in developing the next generation of immunotherapies for cancer and infectious diseases, announced that it has entered into a Memorandum of Understanding (MoU) with FusionVax, Inc. ("FusionVax") setting forth the main terms under which Advaxis will, subject to the entry of a definitive agreement, exclusively license its lead clinical stage product candidate, ADXS-HPV, to FusionVax for Asia. [More]
BIND Therapeutics presents positive Phase 1 clinical study results for BIND-014 at AACR meeting

BIND Therapeutics presents positive Phase 1 clinical study results for BIND-014 at AACR meeting

BIND Therapeutics, a clinical-stage biopharmaceutical company developing a new class of highly selective targeted and programmable therapeutics called AccurinsTM, announced today that positive Phase 1 clinical data for BIND-014, the company's lead drug candidate, were presented today in an oral presentation at the American Association for Cancer Research 2013 Annual Meeting. [More]
Scientists figure out how to dodge HPV-triggered cancers by vaccination

Scientists figure out how to dodge HPV-triggered cancers by vaccination

In 2009, more than 30,000 people in the U.S. learned they had cancer linked to the human papillomavirus, or HPV. This virus is best known for causing cervical cancer, but it's also the culprit behind many cancers of the mouth, throat, anus, and genitals. Unlike many forms of cancer, for which we lack the knowledge and tools to prevent, scientists have figured out how to dodge HPV-triggered cancers — by HPV vaccination. [More]
Study to determine prevalence of abnormal anal cytology and HPV in at-risk women

Study to determine prevalence of abnormal anal cytology and HPV in at-risk women

A basic connection of statistics lead a researcher at Women & Infants Hospital of Rhode Island to question whether women should be screened for anal cancer during a regular visit to the gynecologist, and what technique is most effective. [More]
Overall cancer death rates continue to decline in the U.S.: Report

Overall cancer death rates continue to decline in the U.S.: Report

The Annual Report to the Nation on the Status of Cancer, 1975-2009, shows that overall cancer death rates continued to decline in the United States among both men and women, among all major racial and ethnic groups, and for all of the most common cancer sites, including lung, colon and rectum, female breast, and prostate. [More]
Infrared therapy could help prevent anal cancer in HIV-positive population

Infrared therapy could help prevent anal cancer in HIV-positive population

Infrared coagulopathy treatment of a potential precursor of anal cancer is effective and warrants further study as a way to reduce anal cancer incidence and mortality among HIV-infected people, report researchers. [More]
HIV infection has been major driver of anal cancer burden

HIV infection has been major driver of anal cancer burden

Rising rates of anal cancer among men in the USA have been heavily influenced by the HIV epidemic since the 1980s, a study shows. [More]

Study determines impact of HIV on anal cancer incidence in the U.S.

The increase in anal cancer incidence in the U.S. between 1980 and 2005 was greatly influenced by HIV infections in males, but not females, according to a study published October 5 in the Journal of the National Cancer Institute. [More]

Rare study highlights anal cancer prognosis risks

The presence of palpable, clinically involved inguinal lymph nodes and male gender are both independent risk factors for poor prognosis in anal cancer, confirm the results of a UK analysis. [More]
College-age children also need immunizations, says UMDNJ professor

College-age children also need immunizations, says UMDNJ professor

Most parents take their young children regularly for immunization shots that protect against polio, diphtheria, measles, mumps and other diseases. But many do not consider that their college-age children also need immunizations. [More]
'Atzelberg Circle' researchers meet to advance hyperthermia as standard combination cancer therapy

'Atzelberg Circle' researchers meet to advance hyperthermia as standard combination cancer therapy

BSD Medical Corporation, a developer and manufacturer of advanced medical systems that utilize heat therapy to treat cancer, announced today that a distinguished, international team of leading oncologists met in council while attending the May 2012 conference of the European Society for Radiotherapy and Oncology (ESTRO) in Barcelona, Spain. [More]
Canadian docs recommend HPV vaccine for boys

Canadian docs recommend HPV vaccine for boys

Girls have had access to free HPV vaccinations for five years - administered to protect them against cervical cancer - and this week, the Canadian Cancer Advocacy Coalition called on provincial governments to pay for the vaccine for boys as well. In January, the National Advisory Committee on Immunization recommended HPV vaccination for males aged nine to 25. [More]

BIND presents results from BIND-014 Phase 1 trial on solid tumors at AACR 2012

BIND Biosciences, a clinical-stage biopharmaceutical company developing a new class of highly selective targeted therapeutics called Accurins, announced today the presentation of late-breaker clinical data for BIND-014, the lead drug candidate within a new class of targeted therapeutics that are programmed to concentrate at tumors, at the American Association for Cancer Research (AACR) 2012 Annual Meeting. [More]

Targeted provider education of HPV vaccination benefits for males critical for achieving vaccination goals

Researchers from Boston University School of Medicine (BUSM) have found that a health care provider's attitude toward male human papillomavirus (HPV) vaccination may influence the implementation of new guidelines. They believe targeted provider education on the benefits of HPV vaccination for male patients, specifically the association of HPV with certain cancers in men, may be important for achieving vaccination goals. [More]
Europe conference to discuss on new HIV indicator diseases

Europe conference to discuss on new HIV indicator diseases

Today, heterosexuals in Europe are at particular risk of carrying HIV for so long that they remain undiagnosed until their immune system starts to fail and they become ill. An international study under the leadership of the HIV in Europe initiative has now revealed that a number of diseases, including herpes zoster and certain forms of cancer, should be on the list of indicators for having HIV - and thus serve to prompt health care professionals to suggest an HIV-test to their patients. [More]
HPV vaccine recommended for boys

HPV vaccine recommended for boys

The American Academy of Pediatrics has recommended boys -; not just girls -; be vaccinated against HPV, though questions about its cost-effectiveness remain. [More]
Oral HPV infection more common in men than women: Study

Oral HPV infection more common in men than women: Study

According to a new US study, oral human papillomavirus (HPV) infection is more common among men than women, leading to an increased risk for men of head and neck cancers. HPV causes the majority of cervical cancers, as well as genital and anal - and head and neck cancers. [More]
HPV transmission via oral sex practices suggests research

HPV transmission via oral sex practices suggests research

A new study suggested that an estimated 7% of American teens and adults carry the human papillomavirus in their mouths. This may help health experts finally understand why rates of mouth and throat cancer have been climbing for nearly 25 years. The evidence additionally makes it clear that oral sex practices play a key role in transmission. [More]