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Anemia is a decrease in normal number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the blood. However, it can include decreased oxygen-binding ability of each hemoglobin molecule due to deformity or lack in numerical development as in some other types of hemoglobin deficiency. The three main classes of anemia include excessive blood loss (acutely such as a hemorrhage or chronically through low-volume loss), excessive blood cell destruction (hemolysis) or deficient red blood cell production (ineffective hematopoiesis). Anemia is the most common disorder of the blood. There are several kinds of anemia, produced by a variety of underlying causes. Anemia can be classified in a variety of ways, based on the morphology of RBCs, underlying etiologic mechanisms, and discernible clinical spectra, to mention a few.
Pfizer’s IBRANCE (palbociclib) now approved for use in women with HR+, HER2- metastatic breast cancer

Pfizer’s IBRANCE (palbociclib) now approved for use in women with HR+, HER2- metastatic breast cancer

Pfizer Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved a new indication expanding the use of IBRANCE (palbociclib) 125mg capsules, Pfizer’s metastatic breast cancer therapy. [More]
Maternal supplementation with docosahexaenoic acid improves fetal iron metabolism

Maternal supplementation with docosahexaenoic acid improves fetal iron metabolism

A research has proven, for the first time, that maternal supplementation with docosahexaenoic acid (DHA), an omega-3 essential polyunsaturated fatty acid, enhances fetal iron metabolism thanks to a greater expression of key genes regulating its transfer through the placenta. [More]
Testosterone treatment for older men improves sexual function, walking ability and mood

Testosterone treatment for older men improves sexual function, walking ability and mood

As men age, their testosterone levels decrease, but prior studies of the effects of administering testosterone to older men have been inconclusive. Now, research shows that testosterone treatment for men over 65 improves sexual function, walking ability and mood, according to a study published in the New England Journal of Medicine by team researchers from the Perelman School of Medicine at the University of Pennsylvania, and twelve other medical centers in the United States, in partnership with the National Institute on Aging. [More]
MemorialCare partners with Fresenius Medical Care to operate 15 dialysis clinics in Southern California

MemorialCare partners with Fresenius Medical Care to operate 15 dialysis clinics in Southern California

MemorialCare Health System announced today that it has entered into a joint venture partnership with Fresenius Medical Care North America to operate 15 dialysis clinics in Orange and Los Angeles counties. Thirteen of these clinics are fully operational and two additional clinics are being developed in San Juan Capistrano and Huntington Beach. [More]
Allergan's sNDA for TEFLARO (ceftaroline fosamil) accepted by FDA

Allergan's sNDA for TEFLARO (ceftaroline fosamil) accepted by FDA

Allergan plc today announced the U.S. Food and Drug Administration has accepted for filing the company's supplemental New Drug Application (sNDA) for TEFLARO (ceftaroline fosamil). [More]
Yale Cancer Center researchers identify cause of myeloma

Yale Cancer Center researchers identify cause of myeloma

Yale Cancer Center researchers have identified what causes a third of all myelomas, a type of cancer affecting plasma cells. The findings, published in the Feb. 11 issue of the New England Journal of Medicine, could fundamentally change the way this cancer and others are treated. [More]
2D-NMR could be a powerful complementary technique for assessing biosimilarity of protein drugs

2D-NMR could be a powerful complementary technique for assessing biosimilarity of protein drugs

A first-ever interlaboratory study of four versions of a therapeutic protein drug—all manufactured from living cells—reports that an established analytical tool akin to magnetic resonance imaging reliably assessed the atomic structures of the biologically similar products, yielding the equivalent of a fingerprint for each. [More]
Eisai's Halaven receives FDA approval for treatment of patients with metastatic liposarcoma

Eisai's Halaven receives FDA approval for treatment of patients with metastatic liposarcoma

Eisai Inc. announced today that the U.S. Food and Drug Administration approved Halaven (eribulin mesylate) Injection (0.5 mg per mL) for the treatment of patients with unresectable or metastatic liposarcoma who have received a prior anthracycline-containing regimen. [More]
Zepatier receives FDA approval for treatment of chronic HCV genotypes 1 and 4 infections

Zepatier receives FDA approval for treatment of chronic HCV genotypes 1 and 4 infections

The U.S. Food and Drug Administration today approved Zepatier (elbasvir and grazoprevir) with or without ribavirin for the treatment of chronic hepatitis C virus (HCV) genotypes 1 and 4 infections in adult patients. [More]
Three Case Western faculty members receive funding to develop new diagnostic technologies

Three Case Western faculty members receive funding to develop new diagnostic technologies

Three Case Western Reserve University faculty members have received funding to further develop emerging technologies aimed at malaria, cystic fibrosis, and sickle cell anemia. [More]
Nearly 3.3 million children in U.S. have dizziness or balance problem

Nearly 3.3 million children in U.S. have dizziness or balance problem

More than 1 in 20 (nearly 3.3 million) children between the ages of 3 and 17 have a dizziness or balance problem, according to an analysis of the first large-scale, nationally representative survey of these problems in U.S. children. [More]
Colorectal cancer in younger patients associated with more advanced disease but better survival

Colorectal cancer in younger patients associated with more advanced disease but better survival

Nearly 15 percent of patients diagnosed with colorectal cancer were younger than 50, the age at which screening recommendations begin. [More]
Simple blood test could help eliminate B12 deficiencies among older adults in long-term care homes

Simple blood test could help eliminate B12 deficiencies among older adults in long-term care homes

A high proportion of older adults entering long-term care homes in Ontario are B12 deficient, with more developing deficiencies over the course of their first year in residence, according to research from the University of Waterloo. There is a connection between B12 deficiency and several serious health conditions. [More]
Mylan releases generic version of Felbatol Tablets in U.S.

Mylan releases generic version of Felbatol Tablets in U.S.

Mylan N.V. today announced the U.S. launch of Felbamate Tablets USP, 400 mg and 600 mg, which is the generic version of Meda Pharms' Felbatol Tablets. Mylan received final approval from the U.S. Food and Drug Administration for its Abbreviated New Drug Application (ANDA) for this product. [More]
UGA study helps solve mystery of how African trypanosomes communicate

UGA study helps solve mystery of how African trypanosomes communicate

While scientists have known for years that African trypanosomes cause sleeping sickness, they've been left scratching their heads as to how these tiny single-celled organisms communicate. A University of Georgia study, published Jan. 14 in the journal Cell, helps solve this mystery. [More]
Pre-existing nutritional deficits, immune dysfunction may increase hepatitis E risk during pregnancy

Pre-existing nutritional deficits, immune dysfunction may increase hepatitis E risk during pregnancy

Researchers from the Johns Hopkins Bloomberg School of Public Health have found a link between pre-existing nutritional deficits and immune dysfunction and the risk of hepatitis E infection during pregnancy. [More]
Researchers discover molecular target for DNA repair defects behind Fanconi anemia

Researchers discover molecular target for DNA repair defects behind Fanconi anemia

Researchers have identified a molecular target and experimental treatment strategy for DNA repair defects behind Fanconi anemia – a complex genetic disorder responsible for birth anomalies, organ damage, anemia and cancer. [More]
“Anemia and Hemoglobin Testing” guide published by EKF Diagnostics

“Anemia and Hemoglobin Testing” guide published by EKF Diagnostics

EKF Diagnostics, the global in vitro diagnostics company, announces the publication of its new guide, “Anemia and hemoglobin testing” . [More]
Researchers identify factors that may predict outcomes in pediatric patients with intracranial GSWs

Researchers identify factors that may predict outcomes in pediatric patients with intracranial GSWs

Researchers from Memphis, Tennessee, have examined intracranial gunshot wounds (GSWs) in children and adolescents, and identified nine clinical, laboratory, and radiological factors that were predictive of these patients' outcomes. [More]
Bayer to present new research findings on Xofigo (radium Ra 223 dichloride) injection at ASCO GU 2016

Bayer to present new research findings on Xofigo (radium Ra 223 dichloride) injection at ASCO GU 2016

Bayer announced today that new research findings on Xofigo (radium Ra 223 dichloride) injection will be presented at the 2016 Genitourinary Cancers Symposium of the American Society of Clinical Oncology (ASCO GU) taking place January 7 – 9 in San Francisco. [More]
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