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Gut bacteria linked to risk of bloodstream infections after chemotherapy

Gut bacteria linked to risk of bloodstream infections after chemotherapy

A new study led by researchers at the University of Minnesota and Nantes University Hospital in France shows that the bacteria in people's gut may predict their risk of life-threatening blood infections following high-dose chemotherapy. [More]
Existing non-antibiotic therapeutic drugs could help combat antibiotic-resistant pathogens

Existing non-antibiotic therapeutic drugs could help combat antibiotic-resistant pathogens

The rise of antibiotic resistant bacterial pathogens is an increasingly global threat to public health. In the United States alone antibiotic resistant bacterial pathogens kill thousands every year. [More]
Researchers determine 3-D structure of RlmN protein from bacteria

Researchers determine 3-D structure of RlmN protein from bacteria

The structure of a bacterial RNA-binding protein has been determined in the act of modifying a molecule of RNA -- an achievement that provides researchers with a unique view of the protein's function in action and could lead to clues that would help in the fight against the development of antibiotic-resistant infections. [More]
Scientists map core genes involved during DNA uptake in strep bacteria

Scientists map core genes involved during DNA uptake in strep bacteria

Bacteria possess the ability to take up DNA from their environment, a skill that enables them to acquire new genes for antibiotic resistance or to escape the immune response. Scientists have now mapped the core set of genes that are consistently controlled during DNA uptake in strep bacteria, and they hope the finding will allow them to cut off the microbes' ability to survive what doctors and nature can throw at them. [More]
NPS MedicineWise reminds Australians to prevent overuse and misuse of antibiotics

NPS MedicineWise reminds Australians to prevent overuse and misuse of antibiotics

Following from last night’s Catalyst episode, ‘Antibiotic Resistance’ on ABC TV examining Australia’s profligate use of antibiotics, NPS MedicineWise is reminding Australians to preserve the miracle of antibiotics by avoiding antibiotics when they’re not needed. [More]
Scientists evaluate phage-based therapy to battle antibiotic-resistant bacterial superbug infections

Scientists evaluate phage-based therapy to battle antibiotic-resistant bacterial superbug infections

Flinders University scientists are looking to bacteriophages – highly specific viruses - as the as the best way to attack antibiotic-resistant bacterial superbug infections. [More]
Researchers develop new mathematical model to evaluate best treatment protocol to clear infection

Researchers develop new mathematical model to evaluate best treatment protocol to clear infection

Antibiotic resistance is one of the most challenging problems in modern medicine. A new study by Erida Gjini and Patricia H. Brito from the Instituto Gulbenkian de Ciência, provides a new mathematical model to evaluate the best treatment protocol to clear an infection, by taking into account the role of the host immune system. [More]
Researchers focus on novel target to treat bacterial infection

Researchers focus on novel target to treat bacterial infection

Bacterial infection takes hold in the body when a pathogenic microorganism delivers toxins to healthy cells. One way bacteria accomplish this is by releasing vesicles, which act as tiny envelopes transporting toxins and other virulence factors to host cells. These toxins allow the bacteria to "make themselves at home" in cells. [More]
Kevin Hollinrake MP, ANTRUK CEO comment on Chancellor George Osborne's IMF speech on antibiotic resistance

Kevin Hollinrake MP, ANTRUK CEO comment on Chancellor George Osborne's IMF speech on antibiotic resistance

Chancellor George Osborne will today warn that resistance to antibiotics will become an “even greater threat to mankind than cancer” without global action. His comments will be presented in a speech at the International Monetary Fund (IMF) meeting in Washington today, 14th April 2016. [More]
Tackling superbugs with antibiotic resistance breakers: an interview with Professor Colin Garner, Chief Executive, Antibiotic Research UK

Tackling superbugs with antibiotic resistance breakers: an interview with Professor Colin Garner, Chief Executive, Antibiotic Research UK

Superbugs – or to give them their correct name, antibiotic resistant bacteria – arise on repeated exposure to antibiotics. In any population of bacteria there will be a few that are antibiotic resistant (approximately 1 in 100 million bacteria). If these bacteria are allowed to grow and multiply, an antibiotic resistant infection results. [More]
UC San Diego receives NIH grant to establish interdisciplinary center to combat antibiotic resistance

UC San Diego receives NIH grant to establish interdisciplinary center to combat antibiotic resistance

Researchers at University of California, San Diego School of Medicine have received a five-year, $9.5-million award from the National Institute of Allergy and Infectious Diseases at the National Institutes of Health to establish an interdisciplinary center to define the systems biology of antibiotic resistance. The program will be led by Bernhard Palsson, PhD, Distinguished Professor of Bioengineering and Pediatrics, and Victor Nizet, MD, professor of pediatrics and pharmacy. [More]
Researchers observe increase in antibiotic resistance genes

Researchers observe increase in antibiotic resistance genes

Around the world, antibiotic use and resistance is increasing while the discovery of new antibiotics has nearly halted. [More]
New study demonstrates diversity, resourcefulness of Vibrio cholera

New study demonstrates diversity, resourcefulness of Vibrio cholera

In humans, cholera is among the world's most deadly diseases, killing as many as 140,000 persons a year, according to World Health Organization statistics. But in aquatic environments far away from humans, the same bacterium attacks neighboring microbes with a toxic spear - and often steals DNA from other microorganisms to expand its own capabilities. [More]
Bacteria uses sensitive, nano-sized pump to transport magnesium

Bacteria uses sensitive, nano-sized pump to transport magnesium

Researchers at UiO and NCMM have discovered that the system used by bacteria to transport magnesium is so sensitive that it can detect a pinch of magnesium salt in a swimming pool. [More]
SymCel joins global initiative to combat antibiotic resistance

SymCel joins global initiative to combat antibiotic resistance

Following the global and joint initiative by the pharmaceutical, biotechnology and diagnostics industries this year to combat antibiotic resistance, demand for innovative solutions is especially high. The event took place in January at the World Economic Forum in Davos. [More]

NTU researchers make breakthrough to tackle growing concern of antibiotic resistance

Scientists at Nanyang Technological University, Singapore have discovered that antibiotics can continue to be effective if bacteria's cell-to-cell communication and ability to latch on to each other are disrupted. [More]
Fecal transplants transfer bacterial viruses that appear to be harmless to humans

Fecal transplants transfer bacterial viruses that appear to be harmless to humans

Communities of viruses can be transferred during fecal transplants, according to a study published this week in mBio, an online open-access journal of the American Society for Microbiology. Fortunately for patients who use this procedure, the viruses found to be transmitted in this study appear to be harmless to humans. [More]
New approach allows noninvasive identification of tumor mutations in lung cancer patients

New approach allows noninvasive identification of tumor mutations in lung cancer patients

Researchers at the Stanford University School of Medicine have devised a way to significantly increase the sensitivity of a technique to identify and sequence DNA from cancer cells circulating in a person's blood. [More]
Study provides better picture of molecular basis for antibiotic resistance

Study provides better picture of molecular basis for antibiotic resistance

Scientists from the University of Leeds have solved a 25-year-old question about how a family of proteins allow bacteria to resist the effects of certain antibiotics. [More]
New research links antibiotic use before age 2 to childhood obesity

New research links antibiotic use before age 2 to childhood obesity

While early antibiotic use has been associated with a number of rare long-term health consequences, new research links antibiotics to one of the most important and growing public health problems worldwide -- obesity. [More]
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