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Microbial community less stable and less diverse in antibiotic-treated children

Microbial community less stable and less diverse in antibiotic-treated children

The DIABIMMUNE project followed the development of 39 Finnish infants from birth to the age of three. Half of the children received 9-15 antibiotic treatments during the research period, and the other half did not receive any such treatments. [More]
Molecular diagnostics of the future: an interview with Elaine Warburton, OBE

Molecular diagnostics of the future: an interview with Elaine Warburton, OBE

Firstly, a sample must be transported from the clinic to the laboratory. Simple tests may be undertaken in a small lab within the hospital or clinic, whilst complex testing such as drug susceptibility testing is often done in a large centralized laboratory many miles from the clinic [More]
Legions of immune cells play complex role to destroy Legionella bacteria

Legions of immune cells play complex role to destroy Legionella bacteria

Immunologists and microbiologists from the University of Melbourne's Bio21 Molecular Science and Biotechnology Institute and the Peter Doherty Institute for Infection and Immunity - a joint venture between the University of Melbourne and Royal Melbourne Hospital - have led a study that defined a new cell type responsible for turning the attack back on the bacteria. [More]
NPS MedicineWise urges Australians to stop expecting antibiotics for colds and flu

NPS MedicineWise urges Australians to stop expecting antibiotics for colds and flu

With new findings launched today showing that antimicrobial use in the community in Australia is higher than in England, Canada, Norway, Denmark, Sweden and the Netherlands—and that the number of antimicrobials being prescribed in Australia continues to grow—NPS MedicineWise is again urging Australians to stop expecting antibiotics for viruses such as colds and flu. [More]
New superbug test developed by TGen-NAU receives Australian patent

New superbug test developed by TGen-NAU receives Australian patent

Antibiotic-resistant infections should be easier to detect, and hospitals could become safer, thanks to a technology developed by the Translational Genomics Research Institute and Northern Arizona University, and protected under a patent issued by Australia. [More]
Cranberries can reduce symptomatic UTIs and avoid chronic suppressive antibiotics

Cranberries can reduce symptomatic UTIs and avoid chronic suppressive antibiotics

Today leading experts on infectious disease and urinary tract infections (UTIs) will gather in London to discuss the alarming state of antibiotic resistance, and present findings from a landmark study that conclusively shows that cranberries can be a nutritional approach to reducing symptomatic UTIs, and as a result, may be a useful strategy to decrease worldwide use of antibiotics. [More]
How can we defeat drug resistance? An interview with Dr Grania Brigden

How can we defeat drug resistance? An interview with Dr Grania Brigden

The O’Neill report is a wide ranging report recognising anti-microbial resistance (AMR) as a global problem with major public health and economic significance. [More]
Tiny molecular scaffolding could be key to fight against antibiotic resistance

Tiny molecular scaffolding could be key to fight against antibiotic resistance

Tiny molecular scaffolding that joins molecules together could be the key to our battle against antibiotic resistance. Research published in Bioorganic & Medicinal Chemistry Letters shows that carbon nanodot scaffolding assembled with small molecules called polyamines can kill some dangerous drug-resistant bacteria, including Acinetobacter baumanii and Klebsiella pneumonia. [More]
Tackling healthcare challenges in a changing world: an interview with Professor Jeremy Nicholson

Tackling healthcare challenges in a changing world: an interview with Professor Jeremy Nicholson

As individuals and as populations our risks of getting diseases are determined partly genetically and partly from the environment that we live in. An important part of that environment that mediates between the outside world and the inside world of our bodies is the microbiome. [More]

Research reveals complicated love story between bacterial virulence and antibiotic resistance

It's thought that antibiotic resistance is associated with a fitness cost, meaning that bacteria that develop antibiotic resistance must sacrifice something in order to do so. Because of this, proper use of antibiotics should result in susceptible strains eventually replacing resistant ones. [More]
New immunization approach may one day wipe out pneumonia, meningitis

New immunization approach may one day wipe out pneumonia, meningitis

A new vaccine allows pneumonia-causing bacteria to colonize inside the body, springing into action only if the bacteria pose a threat. [More]
Researchers examine pan-genome of deadly Staph bacteria

Researchers examine pan-genome of deadly Staph bacteria

Staphylococcus aureus bacteria are the leading cause of skin, soft tissue and several other types of infections. Staph is also a global public threat due to the rapid rise of antibiotic-resistant strains, including methicillin-resistant Staphylococcus aureus or MRSA. [More]
Cigarette smoke promotes bacteria colonization, immune invasion

Cigarette smoke promotes bacteria colonization, immune invasion

The mouth is one of the "dirtiest" parts of the body, home to millions of germs. But puffing cigarettes can increase the likelihood that certain bacteria like Porphyromonas gingivalis will not only set up camp but will build a fortified city in the mouth and fight against the immune system. [More]
Phage therapy in conjunction with antibiotics could help treat dangerous bacterial infection

Phage therapy in conjunction with antibiotics could help treat dangerous bacterial infection

Yale researchers were fishing for a new weapon against antibiotic resistance and found one floating in a Connecticut pond, they report May 26, 2016 in the journal Scientific Reports. [More]
First clinical trial to study use of Chinese Herbal Medicines in treating RUTIs

First clinical trial to study use of Chinese Herbal Medicines in treating RUTIs

Researchers at the University of Southampton are to study the use of Chinese Herbal Medicines in treating recurrent urinary tract infections (RUTIs), in the first clinical trial of its kind in the UK. [More]
Understanding structure of HIV-1 protease vital to development of next-generation HIV drugs

Understanding structure of HIV-1 protease vital to development of next-generation HIV drugs

HIV, the virus that causes AIDS, has become one of the world’s most serious health and development challenges. [More]
Harvard researchers create new, simplified platform for antibiotic discovery

Harvard researchers create new, simplified platform for antibiotic discovery

Harvard researchers have created a new, greatly simplified, platform for antibiotic discovery that may go a long way to solving the crisis of antibiotic resistance. [More]

New Quick Reference Guide set to improve antibiotic prescribing

A Tasmanian initiative to provide a ‘Quick Reference Guide’ to antibiotic prescribing in the community has been embraced by general practitioners (GPs) and is set to improve prescribing, delegates at the National Medicines Symposium in Canberra have heard. [More]
More neonatal infection research could drive forward measures to reduce infant deaths

More neonatal infection research could drive forward measures to reduce infant deaths

No one knows how many newborns are dying each year due to antibiotic resistant infections, because of a lack of funding to research the issue fully, Professor Mike Sharland from St George's, University London said. [More]
Scientists identify new hots pots of antibiotic resistance

Scientists identify new hots pots of antibiotic resistance

Antibiotic-resistant bacteria most often are associated with hospitals and other health-care settings, but a new study indicates that chicken coops and sewage treatment plants also are hot spots of antibiotic resistance. [More]
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