Antihypertensive Drug News and Research

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Hypertensive patients rely on medication rather than decreasing salt intake

Patients with high blood pressure are relying solely on medication to reduce their risk of heart attack, stroke and heart failure, rather than decreasing salt intake as instructed by their physicians, according to research presented today at ESC Congress 2018, the annual meeting of the European Society of Cardiology.

27 Aug 2018

Combination of diabetes and hypertension drugs can effectively treat cancer

A combination of a diabetes medication and an antihypertensive drug can effectively combat cancer cells.

27 Dec 2016

Aspirin resistance signals increased stroke severity

Stroke severity and infarct volume are significantly increased among patients who become resistant to aspirin, show study findings published in Neurology.

12 Apr 2016

ReCor gets FDA IDE approval to evaluate ReCor Paradise Renal Denervation System in patients with hypertension

ReCor Medical announced today that it has received FDA IDE approval for the RADIANCE-HTN clinical trial to evaluate the effect of the ReCor Paradise Renal Denervation System on blood pressure in patients with hypertension.

22 Feb 2016

Delivering novel formulation of propranolol as liquid salt may reduce skin toxicity

Formulating drugs as liquid salts may provide a safe and efficient strategy for topical delivery of drugs that cause skin toxicity. A team of researchers from the University of California, Santa Barbara (UCSB) in Santa Barbara, CA has demonstrated a novel formulation of propranolol as a liquid salt which enables delivery through skin with reduced toxicity.

30 Dec 2015

ATTEMPT-CVD trial results show that ARBs may have better impact on CVD biomarkers

When it comes to treating high blood pressure, not all anti-hypertensive medications are equal, and results of the ATTEMPT-CVD trial suggest that telmisartan, an angiotensin II receptor blocker (ARB) might have benefits over non-ARB treatment.

31 Aug 2015

FDA-approved antihypertensive drug can stop cocaine and alcohol addiction

Researchers at The University of Texas at Austin have successfully stopped cocaine and alcohol addiction in experiments using a drug already approved by the U.S. Food and Drug Administration (FDA) to treat high blood pressure. If the treatment is proven effective in humans, it would be the first of its kind -- one that could help prevent relapses by erasing the unconscious memories that underlie addiction.

23 Jun 2015

Spironolactone drug reduces side effects of corticosteroid-based dermatological creams

Basic research on blood pressure has led researchers from Inserm (Inserm Unit 1138, "Cordeliers Research Centre") to obtain unexpected results: drugs used to treat hypertension (high blood pressure) reduce side effects from corticosteroid-based creams used to treat certain skin diseases.

19 Mar 2015

Actavis receives complete response letter for nebivolol/valsartan FDC for treatment of hypertension

Actavis plc today confirmed that the Company has received a complete response letter from the U.S. Food and Drug Administration (FDA) for its New Drug Application (NDA) for the fixed-dose combination (FDC) of nebivolol and valsartan for the treatment of hypertension.

25 Dec 2014

Team-based care shown to be most effective way to control hypertension

Patients diagnosed with high blood pressure are given better control of their condition from a physician-pharmacist collaborative intervention than physician management alone, according to new research.

22 Oct 2014

Hypertensive patients who have psoriasis may need stricter blood pressure control

People with hypertension who also have psoriasis may benefit from tighter blood pressure control, say researchers, particularly if their psoriasis is moderate or severe.

16 Oct 2014

Healthy lifestyle helps hard-to-treat hypertensive patients

Maintaining a healthy lifestyle can prevent cardiovascular events even among patients with apparent treatment-resistant hypertension, say researchers.

15 Jul 2014

Systolic, diastolic blood pressures may have different effects on different types of cardiovascular diseases

Raised systolic and diastolic blood pressures may have different effects on different types of cardiovascular diseases and at different ages, according to new research involving 1.25 million patients from primary care practices in England published in a special themed issue of The Lancet.

31 May 2014

Simple approach best for blood pressure risk stratification

Calculating blood pressure load does not increase physicians’ ability to predict a patient’s risk of cardiovascular events, research shows.

3 Mar 2014

Treatable factors linked to blood pressure variability in diabetes

Some factors that are associated with variability in home blood pressure in patients with Type 2 diabetes may be open to intervention, research suggests.

25 Feb 2014

Physicians beware of fruity drug interactions

An understanding of the potential for pharmacokinetic interaction between orally administered drugs and grapefruit is necessary in view of an increase in marketed medications that fit the risk criteria, suggest Canadian researchers.

30 Nov 2012

Comprehensive overview of vascular risk factors to Alzheimer's disease

Over the last 15 years, researchers have found a significant association between vascular diseases such as hypertension, atherosclerosis, diabetes type 2, hyperlipidemia, and heart disease and an increased risk of Alzheimer's disease.

6 Nov 2012

Men with cardiovascular risk factors more likely to develop peripheral artery disease

Among nearly 45,000 men who were followed up for more than two decades, those with the risk factors of smoking, hypertension, high cholesterol, and type 2 diabetes had an associated greater risk of developing PAD, according to a study in the October 24/31 issue of JAMA.

24 Oct 2012

Study examines link between alcohol consumption and AF in patients with cardiovascular disease

An analysis of the association of alcohol consumption with the development of atrial fibrillation (AF) among subjects with coronary heart disease, stroke, diabetes, or other manifestations of cardiovascular disease (CVD) was based on subjects in two large antihypertensive drug treatment trials.

15 Oct 2012

Oil blend plus antihypertensive lowers blood pressure, cholesterol level

A blend of sesame and rice bran oil could reduce blood pressure by almost as much as an antihypertensive medication, say researchers.

1 Oct 2012