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Artemisinin is a drug used to treat multi-drug resistant strains of falciparum malaria. The compound (a sesquiterpene lactone) is isolated from the plant Artemisia annua. Not all plants of this species contain artemisinin.
Discovery may help researchers identify new ways to attack malaria parasite

Discovery may help researchers identify new ways to attack malaria parasite

New anti-malarial drugs could be developed after researchers discovered a new mechanism used by the malaria parasite when it infects humans. [More]
Researchers identify 124 protein targets of artemisinin in most pathogenic malaria parasite

Researchers identify 124 protein targets of artemisinin in most pathogenic malaria parasite

A team of researchers from the National University of Singapore (NUS) has uncovered the mystery behind the potent parasite-killing effect of artemisinin, a drug that is considered to be the last line of defence against malaria. Given the emergence of artemisinin resistance, these findings could potentially lead to the design of new treatments against drug-resistant parasites. [More]
NUS scientists uncover mystery behind potent parasite-killing effect of artemisinin

NUS scientists uncover mystery behind potent parasite-killing effect of artemisinin

A team of researchers from the National University of Singapore has uncovered the mystery behind the potent parasite-killing effect of artemisinin, a drug that is considered to be the last line of defence against malaria. Given the emergence of artemisinin resistance, these findings could potentially lead to the design of new treatments against drug-resistant parasites. [More]

Less effective drugs can help beat malaria more effectively

Oxford University scientists have found that the more effective way to beat malaria is to use less effective drugs some of the time. [More]
Researchers demonstrate new screening model to identify drug targets for the most lethal strain of malaria

Researchers demonstrate new screening model to identify drug targets for the most lethal strain of malaria

A University of South Florida Center for Global Health & Infectious Diseases Research team has demonstrated a new screening model to classify antimalarial drugs and to identify drug targets for the most lethal strain of malaria, Plasmodium falciparum. [More]
GHIT Fund invests $10.7 million to fight malaria, TB, leishmaniasis and dengue

GHIT Fund invests $10.7 million to fight malaria, TB, leishmaniasis and dengue

The Global Health Innovative Technology Fund, which in the last two years has invested US$43 million to develop innovative tools for fighting diseases worldwide, today announced it is investing $10.7 million at multiple points in the product development pipeline to seek new interventions for malaria, tuberculosis (TB), leishmaniasis and dengue. [More]
New anti-malarial ‘biobricks' could pave way for easier, cost-effective production of artemisinin drug

New anti-malarial ‘biobricks' could pave way for easier, cost-effective production of artemisinin drug

Students from Trinity College Dublin have successfully created anti-malarial ‘biobricks', which could pave the way for easier and more cost-effective production of the key drug artemisinin. [More]

Malaria death rates reduce by 60% since 2000, shows WHO-UNICEF report

Malaria death rates have plunged by 60 per cent since 2000, translating into 6.2 million lives saved, the vast majority of them children, according to a joint WHO-UNICEF report released today. [More]
Health providers still prescribing expensive malaria drugs in Nigeria to patients who do not have malaria

Health providers still prescribing expensive malaria drugs in Nigeria to patients who do not have malaria

Health providers trained to perform malaria rapid diagnostic tests (RDT) are still prescribing valuable malaria medicines to patients who do not have malaria, according to new research published in PLOS ONE. [More]
WHO and health cluster partners cope with health needs of internally displaced persons in South Sudan

WHO and health cluster partners cope with health needs of internally displaced persons in South Sudan

The World Health Organization and partners are racing to cope with the health needs of thousands of internally displaced persons (IDPs) in northeastern South Sudan where fighting continues and the humanitarian situation remains dire. [More]
Opioids produced by yeast; revealing the potential for cheaper pain relief

Opioids produced by yeast; revealing the potential for cheaper pain relief

Researchers at Stanford University have genetically engineered yeast so it produces hydrocodone, a semi-synthetic opioid analgesic used in the United States for relief of moderate to severe pain. [More]
New drug DSM265 shows potential to cure, prevent malaria

New drug DSM265 shows potential to cure, prevent malaria

Researchers at UT Southwestern Medical Center and in Australia have shown that a drug currently in testing shows potential to cure malaria in a single dose and offers promise as a preventive treatment as well. [More]
Artemisinin and the fight against malaria: an interview with Dr. Robert Sebbag, Sanofi

Artemisinin and the fight against malaria: an interview with Dr. Robert Sebbag, Sanofi

Since 2014, more than 16 million anti-malarial treatments derived from the Sanofi patented process for semi-synthetic artemisinin have been supplied to endemic countries in Africa. [More]
WHO calls on global health community to address significant gaps in prevention, treatment of malaria

WHO calls on global health community to address significant gaps in prevention, treatment of malaria

WHO is calling on the global health community to urgently address significant gaps in the prevention, diagnosis and treatment of malaria. Despite dramatic declines in malaria cases and deaths since 2000, more than half a million lives are still lost to this preventable disease each year. [More]
Study explores artemisinin resistance in Plasmodium falciparum malaria

Study explores artemisinin resistance in Plasmodium falciparum malaria

According to the World Health Organization's 2014 World Malaria Report, there are an estimated 198 million cases of malaria worldwide with 3.3 billion people at risk for contracting the infection. Although the impact of malaria is still significant, the statistics reflect a considerable reduction in the global malaria burden. Since 2010, disease transmission has been reduced by 30 percent and mortality due to malaria has decreased by almost half. [More]
Malaria parasites with Ap2mu gene mutation less sensitive to antimalarial drug artemisinin

Malaria parasites with Ap2mu gene mutation less sensitive to antimalarial drug artemisinin

Early indicators of the malaria parasite in Africa developing resistance to the most effective drug available have been confirmed, according to new research published in Antimicrobial Agents and Chemotherapy. [More]
Canada-US researchers to jointly study effectiveness of AIO treatment in patients with late stage cancer

Canada-US researchers to jointly study effectiveness of AIO treatment in patients with late stage cancer

Canadian and American health-care professionals will work together to study the effectiveness of advanced integrative oncology (AIO) treatment for patients with late stage cancer. AIO treatment includes elements of conventional and naturopathic medicine. [More]

Scientists successfully produce highly effective medication for malaria from plant waste material

Professor Peter H. Seeberger, Professor Andreas Seidel-Morgenstern and their team are successful in producing a low-cost but highly effective medication for malaria from plant waste material. For their findings, they received the $25,000 award “Humanity in Science” during Pittcon 2015 in New Orleans. [More]

Two researchers win Humanity in Science prize for developing new antimalarial drug production methods

Prof. Dr. Peter H. Seeberger, a director at the Max Planck Institute of Colloids and Interfaces in Potsdam and a professor of chemistry at Freie Universität Berlin, and Prof. Dr.-Ing. Andreas Seidel-Morgenstern, a director at the Max Planck Institute for Dynamics of Complex Technical Systems in Magdeburg and a professor of chemical engineering at the Otto-von Guericke-University in Magdeburg, won the Humanity in Science prize for their groundbreaking work in developing new production methods for antimalarial drugs. [More]
Dengue fever circulating in urban areas of West Africa

Dengue fever circulating in urban areas of West Africa

Misdiagnosis of febrile illnesses as malaria is a continuing problem in Africa. A new study shows that in Ghana, dengue fever is circulating in urban areas and going undiagnosed. The authors of the study hope to use the findings to launch a widespread initiative to better understand acute undifferentiated febrile illnesses in West Africa. [More]
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