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Many people start to feel pain and stiffness in their bodies over time. Sometimes their hands or knees or shoulders get sore and are hard to move and may become swollen. These people may have arthritis. Arthritis may be caused by inflammation of the tissue lining the joints. Some signs of inflammation include redness, heat, pain, and swelling. These problems are telling you that something is wrong. Joints are places where two bones meet, such as your elbow or knee. Over time, in some types of arthritis but not in all, the joints involved can become severely damaged. There are different types of arthritis. In some diseases in which arthritis occurs, other organs, such as your eyes, your chest, or your skin, can also be affected. Some people may worry that arthritis means they won’t be able to work or take care of their children and their family. Others think that you just have to accept things like arthritis.
Cornell researchers develop chemical probe activated by UV light to control inflammation

Cornell researchers develop chemical probe activated by UV light to control inflammation

Black light does more than make posters glow. Cornell researchers have developed a chemical tool to control inflammation that is activated by ultraviolet (UV) light. [More]
World traveler resumes active lifestyle after partial knee replacement surgery

World traveler resumes active lifestyle after partial knee replacement surgery

David Morris of Alexandria, Virginia has a fascinating job that takes him all over the world. So when arthritis and unrelenting knee pain put a crimp in his active lifestyle, he thought it was time to consider knee replacement. [More]
AAOS: Shoulder replacement surgeries skyrocketing nationally

AAOS: Shoulder replacement surgeries skyrocketing nationally

The number of shoulder replacement surgeries has skyrocketed nationally and at Loyola University Medical Center as technology improves and aging Baby Boomers seek to relieve pain and restore function to arthritic shoulders. [More]
Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Multiple sclerosis is an autoimmune disease in which the body's immune system attacks the patient's own cells. [More]
Experts explore if DXA-derived measurements could predict fracture risk in diabetic patients

Experts explore if DXA-derived measurements could predict fracture risk in diabetic patients

Increased risk of fracture has been shown to be one of the complications arising from longstanding diabetes. With the worldwide increase in Type 2 Diabetes (T2D), in part due to aging populations, there is also increasing concern about how to identify and manage patients with diabetes who are at high risk of osteoporotic fracture. [More]
Type 2 diabetes linked to long list of complications that can affect health and quality of life

Type 2 diabetes linked to long list of complications that can affect health and quality of life

T2D Lifestyle, a national survey by Health Union of more than 400 individuals living with type 2 diabetes (T2D), reveals that patients not only struggle with commonly understood complications, but also numerous lesser known ones that people do not associate with diabetes. [More]
Symptom trends may help predict recovery of patients suffering from post-concussion syndrome

Symptom trends may help predict recovery of patients suffering from post-concussion syndrome

Researchers at the Krembil Neuroscience Centre's Canadian Concussion Centre have identified symptom trends that may not only help predict how soon patients suffering from post-concussion syndrome (PCS) will recover, but also provide insight on how to treat those who experience persistent concussion symptoms. [More]
TUM scientists uncover molecular mechanisms of inhibitors that can selectively thwart immunoproteasome

TUM scientists uncover molecular mechanisms of inhibitors that can selectively thwart immunoproteasome

The immunoproteasome dismantles proteins and the resulting fragments are displayed on the surface of cells. This helps the immune system to recognize abnormal cells. However, in chronic inflammations and autoimmune diseases this “information channel” is overactive. [More]
Early life history and genetics may play crucial role in shaping gut microbiome

Early life history and genetics may play crucial role in shaping gut microbiome

Genetics and birthplace have a big effect on the make-up of the microbial community in the gut, according to research published Nov. 28. in the journal Nature Microbiology. [More]
New anti-inflammatory drug reduces death of existing brain cells then repairs damage after stroke

New anti-inflammatory drug reduces death of existing brain cells then repairs damage after stroke

Researchers at The University of Manchester have discovered that a potential new drug reduces the number of brain cells destroyed by stroke and then helps to repair the damage. [More]
Research shows mechanism that induces heart arrhythmias in diabetic mice

Research shows mechanism that induces heart arrhythmias in diabetic mice

One of the most serious complications of diabetes, heart arrhythmias, is now on its way to be prevented and combated. [More]
Study offers important insights into link between mental disorders and physical diseases

Study offers important insights into link between mental disorders and physical diseases

Mental disorders and physical diseases frequently go hand in hand. For the first time, psychologists at the University of Basel and Ruhr University Bochum have identified temporal patterns in young people: arthritis and diseases of the digestive system are more common after depression, while anxiety disorders tend to be followed by skin diseases. [More]
Decision aid for OA helps increase rate of total knee replacement among black patients

Decision aid for OA helps increase rate of total knee replacement among black patients

A decision aid that consisted of a video that describes the risks and benefits of total knee replacement surgery significantly increased the rate of this surgery among black patients, according to a study published online by JAMA Surgery. [More]
Research reveals key role of fibroblasts in development of rheumatoid arthritis

Research reveals key role of fibroblasts in development of rheumatoid arthritis

A study led by researchers at the University of Birmingham reveals the key role of different types of fibroblast cells in the development of rheumatoid arthritis (RA), opening up a new avenue for research into treatment of the disease. [More]
TSRI scientists unravel mystery of ‘food coma’ phenomenon

TSRI scientists unravel mystery of ‘food coma’ phenomenon

Anyone who has drifted into a fuzzy-headed stupor after a large holiday meal is familiar with the condition commonly known as a "food coma." [More]
TSRI scientists offer novel structure-based drug design strategy for better breast cancer treatment

TSRI scientists offer novel structure-based drug design strategy for better breast cancer treatment

While there have been advances in the treatment of hormone-driven breast cancer, resistance to these therapies remains a significant problem. [More]
Scientists reveal key details of the body's immune response to fungal infections

Scientists reveal key details of the body's immune response to fungal infections

Every year, fungal infections threaten thousands of patients -- from those with depressed immune systems to others who have had surgeries or devices such as catheters implanted. Moreover, some anti-fungal medications are beginning to lose their power. [More]
Arthritis drug induces response and remission in patients with Crohn's disease, study finds

Arthritis drug induces response and remission in patients with Crohn's disease, study finds

Researchers at University of California San Diego School of Medicine have shown that ustekinumab, a human antibody used to treat arthritis, significantly induces response and remission in patients with moderate to severe Crohn's disease. [More]
Psoriatic arthritis patients experience multiple symptoms that can make diagnosis difficult, survey reveals

Psoriatic arthritis patients experience multiple symptoms that can make diagnosis difficult, survey reveals

Psoriatic arthritis (PsA) is an inflammatory condition closely related to and most often co-occurring with psoriasis. [More]
New study to explore ways of helping chronic pain patients get back to work

New study to explore ways of helping chronic pain patients get back to work

Researchers from the University of Warwick's Medical School are leading a novel study to explore ways of helping people with chronic pain back to work. [More]
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