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Many people start to feel pain and stiffness in their bodies over time. Sometimes their hands or knees or shoulders get sore and are hard to move and may become swollen. These people may have arthritis. Arthritis may be caused by inflammation of the tissue lining the joints. Some signs of inflammation include redness, heat, pain, and swelling. These problems are telling you that something is wrong. Joints are places where two bones meet, such as your elbow or knee. Over time, in some types of arthritis but not in all, the joints involved can become severely damaged. There are different types of arthritis. In some diseases in which arthritis occurs, other organs, such as your eyes, your chest, or your skin, can also be affected. Some people may worry that arthritis means they won’t be able to work or take care of their children and their family. Others think that you just have to accept things like arthritis.
Research could pave way for more effective drugs to treat inflammation

Research could pave way for more effective drugs to treat inflammation

Six Case Western Reserve scientists are part of an international team that has discovered two compounds that show promise in decreasing inflammation associated with diseases such as ulcerative colitis, arthritis and multiple sclerosis. [More]
Study identifies new signaling pathway that leads to inflammatory bone erosion in RA patients

Study identifies new signaling pathway that leads to inflammatory bone erosion in RA patients

A new study by researchers at Hospital for Special Surgery identifies a new signaling pathway that contributes to the development and progression of inflammatory bone erosion, which occurs in patients with rheumatoid arthritis (RA). Rheumatoid arthritis is a systemic inflammatory autoimmune disease that affects millions of adults worldwide. [More]
Analgesics, anti-inflammatory drugs have beneficial effect on treatment of depression

Analgesics, anti-inflammatory drugs have beneficial effect on treatment of depression

Ordinary over the counter painkillers and anti-inflammatory drugs purchased from pharmacies may also be effective in the treatment of people suffering of depression. [More]
Regeneron, Sanofi announce initiation of dupilumab Phase 3 study in adults with atopic dermatitis

Regeneron, Sanofi announce initiation of dupilumab Phase 3 study in adults with atopic dermatitis

Regeneron Pharmaceuticals, Inc. and Sanofi today announced that the first patients have been dosed in a Phase 3 clinical study of dupilumab, an investigational therapy that blocks IL-4 and IL-13 signaling, in adults with moderate-to-severe atopic dermatitis (AD) that is not adequately controlled with topical AD medications. [More]
New preclinical imaging product line launched by MILabs at the 2014 Annual European Association of Nuclear Medicine Meeting

New preclinical imaging product line launched by MILabs at the 2014 Annual European Association of Nuclear Medicine Meeting

MILabs BV has launched a complete new preclinical product line at the 2014 Annual European Association of Nuclear Medicine Meeting in Gothenburg, Sweden, October 18-22 (www.eanm.org). It consists of the new 4-series comprising U-SPECT4, U-SPECT4CT, VECTor4 and VECTor4CT incorporating significant improvements over the former PLUS-series. The 4-series carries even further the tradition of MILabs to deliver the best SPECT and PET image resolution available in the market. [More]
Scientists identify two microRNA molecules that control chronic inflammation

Scientists identify two microRNA molecules that control chronic inflammation

University of Utah scientists have identified two microRNA molecules that control chronic inflammation, a discovery that one day may help researchers prevent certain fatal or debilitating conditions before they start. [More]
Researchers identify two microRNA molecules that control chronic inflammation

Researchers identify two microRNA molecules that control chronic inflammation

University of Utah scientists have identified two microRNA molecules that control chronic inflammation, a discovery that one day may help researchers prevent certain fatal or debilitating conditions before they start. [More]
Patients with severe psoriasis more likely to have uncontrolled hypertension, shows research

Patients with severe psoriasis more likely to have uncontrolled hypertension, shows research

Patients with more severe psoriasis are also more likely to have uncontrolled hypertension, according to new research by a team at the Perelman School of Medicine at the University of Pennsylvania. [More]
Johnson & Johnson's sales increase 5.1% to $18.5 billion in Q3 2014

Johnson & Johnson's sales increase 5.1% to $18.5 billion in Q3 2014

Johnson & Johnson today announced sales of $18.5 billion for the third quarter of 2014, an increase of 5.1% as compared to the third quarter of 2013. Operational results increased 5.8% and the negative impact of currency was 0.7%. Domestic sales increased 11.6%. International sales decreased 0.3%, reflecting operational growth of 1.0% and a negative currency impact of 1.3%. [More]
Issues on coverage: Steep Rx costs; federal plan eliminates 'transgender exclusion'

Issues on coverage: Steep Rx costs; federal plan eliminates 'transgender exclusion'

Even patients with insurance are finding that specialty drugs can quickly eat a hole in their wallets because insurers are often putting them in a special tier and demanding high consumer co-payments. Also, the State Department is getting rid of the "transgender exclusion" in it largest health plan, and some consumer advocates are suggesting that people getting coverage on the health marketplaces be allowed to get "wrap-around" plans through their employers. [More]
National Psoriasis Foundation to hold free psoriatic arthritis program in Seattle

National Psoriasis Foundation to hold free psoriatic arthritis program in Seattle

If you're one of the roughly 28,000 Seattle metro residents struggling with pain from psoriatic arthritis (PsA)—an inflammatory autoimmune disease that causes pain, swelling and stiffness of the joints and tendons—learn to control your condition with Be Joint Smart, a free psoriatic arthritis program presented by the National Psoriasis Foundation, at the Double Tree Suites Southcenter on November 8. [More]
BIDMC scientists uncover new class of molecules that protects against diabetes

BIDMC scientists uncover new class of molecules that protects against diabetes

Scientists at the Salk Institute and Beth Israel Deaconess Medical Center in Boston have discovered a new class of molecules—produced in human and mouse fat—that protects against diabetes. [More]
TSRI, STSI researchers receive NIH grants to set up platforms to mine biomedical data

TSRI, STSI researchers receive NIH grants to set up platforms to mine biomedical data

San Diego researchers at The Scripps Research Institute and Scripps Translational Science Institute will receive more than $4.4 million as part of a National Institutes of Health initiative called "Big Data to Knowledge" (BD2K). [More]
Discovery offers promising new avenue for prevention, treatment of type 2 diabetes

Discovery offers promising new avenue for prevention, treatment of type 2 diabetes

The surprising discovery of a previously unidentified class of lipid molecules that enhance insulin sensitivity and blood sugar control offers a promising new avenue for the prevention and treatment of type 2 diabetes. [More]
New Colombia creates joint venture to produce cannabis and hemp based medicinal products

New Colombia creates joint venture to produce cannabis and hemp based medicinal products

New Colombia Resources, Inc., a U.S. company with coal and other resource assets in Colombia, is pleased to announce they have formed a joint venture to produce cannabis and hemp based medicinal products in Colombia in association with an indigenous community in Colombia. [More]
Scientists say fundamental theory about how thymus educates immune police appears to be wrong

Scientists say fundamental theory about how thymus educates immune police appears to be wrong

A fundamental theory about how our thymus educates our immune police appears to be wrong, scientists say. [More]
Researchers are developing compounds to combat causative agents of periodontitis

Researchers are developing compounds to combat causative agents of periodontitis

A total 12 million Germans suffer from periodontitis. If the inflammation remains untreated, this could lead to tooth loss. However, it is also suspected of triggering many other diseases, like cardiopulmonary diseases. Researchers are studying the interactions, and developing compounds to combat the causative agents. [More]
NIH announces high-risk, high-reward grants for UCSF researchers

NIH announces high-risk, high-reward grants for UCSF researchers

UC San Francisco researchers received five awards announced this week by the National Institutes of Health (NIH) for high-risk, high-reward scientific research projects. Their work will focus on novel approaches for diagnosing and treating diseases ranging from autoimmune and chronic inflammatory diseases, to cancer, diabetes and neurological disorders. [More]
Magnesium essential to the activity of vitamin D

Magnesium essential to the activity of vitamin D

Extensive research has shown that vitamin D deficiencies play a major role in the development of dozens of diseases, including breast, prostate and colon cancer, as well as diabetes, heart disease, arthritis, osteoporosis, psoriasis and mental illness. [More]
Physical therapy before joint replacement surgery reduces need for postoperative care by nearly 30%

Physical therapy before joint replacement surgery reduces need for postoperative care by nearly 30%

Physical therapy after total hip (THR) or total knee replacement (TKR) surgery is standard care for all patients. A new study, appearing in the October 1 issue of the Journal of Bone & Joint Surgery), also found that physical therapy before joint replacement surgery, or "prehabilitation," can diminish the need for postoperative care by nearly 30 percent, saving an average of $1,215 per patient in skilled nursing facility, home health agency or other postoperative care. [More]