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Diabetes drug dulaglutide may reduce symptoms of depression

The current study highlighted the antidepressant effects of dulaglutide using the CMS depression model. Notably, the potential metabolisms that underlie the antidepressant effect of dulaglutide have been elucidated in this study.

8 Mar 2024

Fenugreek seeds: A superfood for health and wellness, says new review

Research highlights the dietary significance and potential applications of fenugreek seeds, emphasizing their role in disease prevention, chronic condition management, and providing nutritional value, including their ability to reduce blood sugar and cholesterol levels.

27 Feb 2024

Paxlovid enhances treatment options for COVID-19 patients

The design, synthesis, and mechanism of action of Paxlovid.

6 Feb 2024

Researchers discover new spiroindolin-1,2-diazepine derivatives with anti-Alzheimer therapeutic potential

In a recent study, researchers designed substituted spiro indolin-1,2-diazepine derivatives '5a–v' with cholinesterase inhibitory activities as anti-Alzheimer's disease agents.

31 Jul 2023

Aspartame intake and cancer risk: What you need to know

Aspartame is a low-calorie sweetener that is approximately 200 times sweeter than sugar and is used to replace sugar and provide sweetness in energy-reduced food, or food with no added sugars.

14 Jul 2023

WHO to declare artificial sweetener aspartame as possible carcinogen

The World Health Organization recently indicated that aspartame will likely be declared a “possible carcinogen to humans.”

29 Jun 2023

Preventing the formation of harmful acrylamides in potato crisps

Researchers have now found out how to stop the formation of harmful acrylamides when deep-frying potatoes to make crisps.

19 Jun 2023

The dynamics and interactions between the skin metabolome, microbiome, and UV exposure

Researchers evaluated metabolic profile changes of the skin in relation to microbiota and UV exposure.

5 May 2023

Are non-nutritive sweeteners harming your gut microbiota?

This paper discusses the impact of non-nutritive sweeteners (NNS) on the gut microbiota, which is essential in maintaining normal gut physiology and health.

18 Apr 2023

Magnetic microrobot probe can quantify the stiffness and traction forces of cell colonies and embryos in vivo

In a recent study published in the journal Science Robotics, a team of researchers created a magnetic microrobot probe that can quantify the stiffness and traction force of tumor cell colonies and developing vertebrate embryos.

29 Jan 2023

Researchers identify plasma metabolomic markers for the Mediterranean diet among pregnant women

A recent study identifies blood metabolomic markers and metabolite panels linked to the Mediterranean diet in pregnant women.

17 Jan 2023

Study offers novel insights into the elongation dynamics of eukaryotic cells

Life depends on the precise functioning of several proteins synthesized in cells by ribosomes. This diverse set of proteins, known as a proteome, is maintained by the robust translation elongation of amino acid sequences taking place in the ribosomes.

5 Jan 2023

Artificial sweetener linked to anxiety-like behavior in mice

Florida State University College of Medicine researchers have linked aspartame, an artificial sweetener found in nearly 5,000 diet foods and drinks, to anxiety-like behavior in mice.

8 Dec 2022

Cryo-electron tomography helps visualize platelet deformation due to SARS-CoV-2 spike protein

Researchers used cellular cryo-electron tomography (cryo-ET) to demonstrate the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein in coronavirus disease 2019 (COVID-19)-triggered severe coagulopathies.

28 Nov 2022

Structural analysis of monkeypox virus H1 dual phosphatase as a pan-poxvirus target

In a new study, researchers determined the 1.8-Å resolution crystal structure of the H1 dual specific phosphatase (DSP) of monkeypox virus (MPXV) that is crucial for viral replication, making it an attractive antiviral target.

5 Oct 2022

Study attributes increased transmissibility of Monkeypox Clade IIb to genomic accordions

In a new study, researchers performed a genomic study of confirmed Monkeypox virus (MPXV) cases diagnosed in Spain between 18 May and 14 July 2022.

4 Oct 2022

Molecular engineered low-cost highly effective RBD-based COVID vaccine

In a recent study posted to the bioRxiv* preprint server, an international team of researchers developed a second-generation severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor binding domain (RBD) antigen (RBD-J6) by molecular engineering with two additional amino acid (aa) substitutions (S383D and L518D mutations) in a hydrophobic cryptic RBD core epitope to enhance stability and expression against SARS-CoV-2 variants of concern (VOCs).

19 Sep 2022