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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.
JAK inhibitors may be first effective treatment for people with alopecia areata

JAK inhibitors may be first effective treatment for people with alopecia areata

Seventy-five percent of patients with moderate to severe alopecia areata—an autoimmune disease that causes patchy, and less frequently, total hair loss—had significant hair regrowth after treatment with ruxolitinib, reported researchers from Columbia University Medical Center. By the end of their treatment, average hair regrowth was 92 percent. [More]
TSRI scientists shed light on molecular workings of MS drug

TSRI scientists shed light on molecular workings of MS drug

A study by scientists at The Scripps Research Institute has helped to de-mystify the molecular workings of the multiple sclerosis (MS) drug Tecfidera. The drug is the most widely prescribed pill-based therapy for MS, but its biological mechanism remains mysterious. [More]
Improving muscle health could enhance response to insulin in Type 1 diabetes patients

Improving muscle health could enhance response to insulin in Type 1 diabetes patients

Loss of physical strength due to muscle deterioration is a complication for people living with Type 1 diabetes that's often overlooked. New research from McMaster University shows it shouldn't be. [More]
Virginia Mason offers totally laparoscopic advanced surgery for removing tumors from pancreas

Virginia Mason offers totally laparoscopic advanced surgery for removing tumors from pancreas

Virginia Mason now offers the totally laparoscopic Whipple procedure as an advanced surgical option for removing tumors from the head of the pancreas. [More]
Researchers identify epigenetic mechanism causing aberrancies in coeliac disease

Researchers identify epigenetic mechanism causing aberrancies in coeliac disease

Researchers at the University of Tampere discovered a mechanism causing aberrancies in coeliac disease and colorectal cancer. [More]
LJI researchers reveal unanticipated way by which neutrophils defend against invading pathogens

LJI researchers reveal unanticipated way by which neutrophils defend against invading pathogens

As an arm of the innate immune system, white blood cells called neutrophils form the first line of defense against invading pathogens. [More]
Researchers discover protein that plays role in onset of type 1 diabetes

Researchers discover protein that plays role in onset of type 1 diabetes

A new study reveals a counterintuitive cellular strategy that may protect insulin-producing cells from destruction during type 1 diabetes. [More]
TSRI researchers find potential way to treat aqueous deficiency dry eye

TSRI researchers find potential way to treat aqueous deficiency dry eye

A new study in animal models, led by scientists at The Scripps Research Institute, suggests that the eye's lacrimal glands can be repaired by injecting a kind of regenerative "progenitor" cell. [More]
Mice study finds new approach to halt cycle of chronic inflammation in lupus

Mice study finds new approach to halt cycle of chronic inflammation in lupus

Molecules that scavenge debris from dying cells appear to halt the cycle of chronic inflammation in lupus, while also enhancing the body's ability to combat flu, according to Duke Health studies in mice. [More]
Drugs designed to target nervous system could control inflammation in the gut, study shows

Drugs designed to target nervous system could control inflammation in the gut, study shows

There's a reason it's called a gut feeling. The brain and the gut are connected by intricate neural networks that signal hunger and satiety, love and fear, even safety and danger. These networks employ myriad chemical signals that include dopamine, a powerful neurotransmitter most famous for its role in reward and addiction. [More]
Hygiene hypothesis: a misleading misnomer? An interview with Professor Sally Bloomfield

Hygiene hypothesis: a misleading misnomer? An interview with Professor Sally Bloomfield

Professor Strachan first proposed the hygiene hypothesis back in 1989. Reviewing the evidence, he suggested that one of the causes of the recent rapid rise in allergic diseases in children was lack of exposure to childhood infections [More]
Thymectomy confers benefit to MG patients who do not have chest tumor, study shows

Thymectomy confers benefit to MG patients who do not have chest tumor, study shows

A new study in the New England Journal of Medicine addresses a question doctors have sought to clarify for decades: whether a surgery conducted since the 1940s benefits the patients it targets. [More]
Scientists improve potential weapon to fight against autoimmune disorders

Scientists improve potential weapon to fight against autoimmune disorders

With a trick of engineering, scientists at the Gladstone Institutes improved a potential weapon against inflammation and autoimmune disorders. Their work could one day benefit patients who suffer from inflammatory bowel disease or organ transplant rejection. [More]
Drug for boosting immune system shows promise as potential new treatment for lupus

Drug for boosting immune system shows promise as potential new treatment for lupus

A drug originally used to boost the immune system is showing promise as a potential new treatment for lupus, Monash University-led research published today (August 9) shows. Lupus is an autoimmune disease, where the immune system attacks the body's own organs and tissues. [More]
Triple therapy approach helps Type 1 diabetes patients improve blood sugar control, lose weight

Triple therapy approach helps Type 1 diabetes patients improve blood sugar control, lose weight

A combination of three medications—dapagliflozin, liraglutide and insulin—helped people with Type 1 diabetes improve blood sugar control and lose weight, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. [More]
Studies highlight key role for vitamin A metabolite retinoic acid in ocular fibrosis

Studies highlight key role for vitamin A metabolite retinoic acid in ocular fibrosis

Mucous membrane pemphigoid is an autoimmune disease that causes inflammation and scarring in mucosal tissues. Affected individuals frequently exhibit scarring in the eye, which can lead to blindness in as many as 20% of patients. [More]
TSRI study unveils new twist in immune biology

TSRI study unveils new twist in immune biology

A new study, led by scientists at The Scripps Research Institute, reveals a surprising twist in immune biology. [More]
New research opens door to influencing immune system

New research opens door to influencing immune system

A new international collaboration involving scientists at The Scripps Research Institute opens a door to influencing the immune system, which would be useful to boost the effectiveness of vaccines or to counter autoimmune diseases such as lupus and rheumatoid arthritis. [More]
Researchers identify key immune differences that could help in development of effective HIV vaccine

Researchers identify key immune differences that could help in development of effective HIV vaccine

One of the main mysteries confounding development of an HIV vaccine is why some people infected with the virus make the desired antibodies after several years, but a vaccine can't seem to induce the same response. [More]
Researchers shed light on involvement of immune system in schizophrenia

Researchers shed light on involvement of immune system in schizophrenia

Using data from the largest ever genetic study of schizophrenia, researchers have shed light on the role of the immune system. [More]
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