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Studies show how overactive immune response may contribute to heart disease in psoriasis patients

Studies show how overactive immune response may contribute to heart disease in psoriasis patients

Psoriasis is well-known for causing too many skin cells on elbows, knees, and across the body, but people living with psoriasis may also be at an increased risk of heart disease. [More]
PD-1 protein could serve as biomarker for predicting survival of lung cancer patients

PD-1 protein could serve as biomarker for predicting survival of lung cancer patients

The biomarker PD-1, a protein, could potentially be used to predict survival or disease-free survival of lung cancer patients who have had the tumour surgically removed. [More]
Researchers unveil new role of thymic dendritic cells in controlling T lymphocyte egress into the blood

Researchers unveil new role of thymic dendritic cells in controlling T lymphocyte egress into the blood

A team of scientists led by Julie Saba, MD, PhD at UCSF Benioff Children's Hospital Oakland, has unveiled a novel role of thymic dendritic cells, which could result in new strategies to treat conditions such as autoimmune diseases, immune deficiencies, prematurity, infections, cancer, and the loss of immunity after bone marrow transplantation. [More]
Study reveals new way to improve stability of common protein drugs

Study reveals new way to improve stability of common protein drugs

Gaining access to important biopharmaceuticals needed to treat illnesses and autoimmune diseases is one of the biggest obstacles developing countries face. [More]
Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Multiple sclerosis is an autoimmune disease in which the body's immune system attacks the patient's own cells. [More]
TUM scientists uncover molecular mechanisms of inhibitors that can selectively thwart immunoproteasome

TUM scientists uncover molecular mechanisms of inhibitors that can selectively thwart immunoproteasome

The immunoproteasome dismantles proteins and the resulting fragments are displayed on the surface of cells. This helps the immune system to recognize abnormal cells. However, in chronic inflammations and autoimmune diseases this “information channel” is overactive. [More]
Salk scientists discover key to amplification of ‘invader’ signals

Salk scientists discover key to amplification of ‘invader’ signals

When a receptor on the surface of a T cell -- a sentry of the human immune system -- senses a single particle from a harmful intruder, it immediately kicks the cell into action, launching a larger immune response. But exactly how the signal from a single receptor, among thousands on each T cell, can be amplified to affect a whole cell has puzzled immunologists for decades. [More]
Researchers gain new insights into how immune response size is controlled

Researchers gain new insights into how immune response size is controlled

Australian and Irish researchers have gained previously unachievable insights into how the size of our immune response is controlled, by developing new imaging and computational biology approaches to follow the behaviour of hundreds of cells. [More]
Researchers discover protein complex that enables 'quality control' of immune T cells

Researchers discover protein complex that enables 'quality control' of immune T cells

The research into T cell development within an organ called the thymus revealed for the first time that a protein complex called LUBAC enables 'quality control' of the cells before they are released into the bloodstream. [More]
New research shows immune paralysis in sepsis patients can be reversed

New research shows immune paralysis in sepsis patients can be reversed

Failure of the immune system during blood poisoning (sepsis) can be reversed by a specific sugar. [More]
Scientists reveal key details of the body's immune response to fungal infections

Scientists reveal key details of the body's immune response to fungal infections

Every year, fungal infections threaten thousands of patients -- from those with depressed immune systems to others who have had surgeries or devices such as catheters implanted. Moreover, some anti-fungal medications are beginning to lose their power. [More]
Psoriatic arthritis patients experience multiple symptoms that can make diagnosis difficult, survey reveals

Psoriatic arthritis patients experience multiple symptoms that can make diagnosis difficult, survey reveals

Psoriatic arthritis (PsA) is an inflammatory condition closely related to and most often co-occurring with psoriasis. [More]
Children born to mothers with rheumatoid arthritis may have increased risk of developing epilepsy

Children born to mothers with rheumatoid arthritis may have increased risk of developing epilepsy

A new study shows a link between mothers with rheumatoid arthritis and children with epilepsy. [More]
Smoking, excess weight may influence how rheumatoid arthritis symptoms improve with treatment

Smoking, excess weight may influence how rheumatoid arthritis symptoms improve with treatment

A study finds that smoking or being overweight makes it more difficult for patients with rheumatoid arthritis to achieve optimal control of inflammation and symptoms, despite standard of care treatment. [More]
Bilingual support group addressing health needs of lupus patients has positive impact, study finds

Bilingual support group addressing health needs of lupus patients has positive impact, study finds

A bilingual support group addressing the psychological and educational needs of patients with lupus and their families is a valuable resource to help them cope, according to a study at Hospital for Special Surgery. [More]
TSRI researchers uncover mechanism behind T cell exhaustion

TSRI researchers uncover mechanism behind T cell exhaustion

In a new study with broad implications for treating cancers and chronic viral infections, scientists at The Scripps Research Institute (TSRI) have uncovered a mechanism behind a phenomenon called “T cell exhaustion.” [More]
Dolomite Bio’s Single Cell RNA-Seq System helps researchers study autoimmune diseases

Dolomite Bio’s Single Cell RNA-Seq System helps researchers study autoimmune diseases

Dolomite Bio’s Single Cell RNA-Seq System is helping researchers at the University of Helsinki to investigate autoimmune diseases. [More]
HSS conducts survey to assess musculoskeletal health needs of surrounding communities

HSS conducts survey to assess musculoskeletal health needs of surrounding communities

Hospital for Special Surgery, which has an Outpatient Center in Stamford, plans to increase outreach and educational programs to meet the needs of surrounding communities. [More]
Low-impact exercise program for seniors helps reduce pain, improve mobility and enhance quality of life

Low-impact exercise program for seniors helps reduce pain, improve mobility and enhance quality of life

It's never too late to reap the benefits of exercise, and that includes older adults with arthritis and other muscle and joint conditions, according to a study. [More]
Scientists discover previously unknown mechanism that prevents autoimmune disease

Scientists discover previously unknown mechanism that prevents autoimmune disease

A previously unknown safety mechanism in our immune system keeps the body free from autoimmune diseases. [More]
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