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Novel approach for imaging immune cell movements identifies initial steps in inflammatory arthritis

Novel approach for imaging immune cell movements identifies initial steps in inflammatory arthritis

Using a novel approach for imaging the movement of immune cells in living animals, researchers from the Massachusetts General Hospital Center for Immunology and Inflammatory Diseases have identified what appear to be the initial steps leading to joint inflammation in a model of inflammatory arthritis. [More]
Salk Institute researchers reveal how to curb immune enthusiasm

Salk Institute researchers reveal how to curb immune enthusiasm

Normally when we think of viruses, from the common cold to HIV, we want to boost people's immunity to fight them. [More]
FishTaco method pinpoints bacterial species responsible for each functional imbalance in microbiome

FishTaco method pinpoints bacterial species responsible for each functional imbalance in microbiome

A growing body of evidence indicates that the trillions of microbes that live on and inside our bodies affect our health. Collectively, these resident microbes form our microbiome. [More]
Research offers new clues to prolong lifespan of the body's disease-fighting NK cells

Research offers new clues to prolong lifespan of the body's disease-fighting NK cells

A team of researchers from Australia and France have uncovered new insights into how to prolong the lifespan of the body's disease-fighting natural killer (NK) cells. [More]
Genetic influence on immune system appears to be higher than previously thought

Genetic influence on immune system appears to be higher than previously thought

Nearly three quarters of immune traits are influenced by genes, new research from King's College London reveals. [More]
Researchers uncover two factors that play crucial role in chronic autoimmune disorders

Researchers uncover two factors that play crucial role in chronic autoimmune disorders

Researchers from Schepens Eye Research Institute of Massachusetts Eye and Ear have uncovered two factors responsible for the chronic, lifelong nature of autoimmune disorders, which tend to "flare up" intermittently in affected patients. [More]

AARDA recognizes AARDA founder and longtime staff as its latest Autoimmune Heroes

American Autoimmune Related Diseases Association (AARDA) announced today its latest Autoimmune Heroes - Founder and Executive Director Virginia Ladd, Director of Operations Jerry Ladd, Assistant Director Patricia Barber and InFocus Editor and Executive Assistant Eula Hoover. [More]
Scientists report new molecular mechanism that could be cause of autoimmune diseases

Scientists report new molecular mechanism that could be cause of autoimmune diseases

Scientists at the Immunology Frontier Research Center (IFReC), Osaka University, Japan, report a new molecular mechanism that could explain the cause of some autoimmune diseases. [More]
Researcher develops new method to accurately identify elusive molecules

Researcher develops new method to accurately identify elusive molecules

Among the most important molecules in the living world are sugars or carbohydrates, which play a vital role in life processes. Sugars provide the main source of fuel for the body, protect muscles from damage and contribute to the immune response. [More]
Dual treatment strategies lengthen lives of mice with skin cancer

Dual treatment strategies lengthen lives of mice with skin cancer

By combining two treatment strategies, both aimed at boosting the immune system's killer T cells, Johns Hopkins researchers report they lengthened the lives of mice with skin cancer more than by using either strategy on its own. [More]
U-M researchers identify gene expression linked to gender differences in autoimmune diseases

U-M researchers identify gene expression linked to gender differences in autoimmune diseases

Women represent nearly 8 out of every 10 people with autoimmune diseases. Although the statistics are well-known, the scientific community is still trying to figure out why women's immune systems are more likely to become overactive and attack their own healthy cells. [More]
Replacing missing gut bacteria could help treat children with rare autoimmune disease

Replacing missing gut bacteria could help treat children with rare autoimmune disease

Defects in the body's regulatory T cells (T reg cells) cause inflammation and autoimmune disease by altering the type of bacteria living in the gut, researchers from The University of Texas Health Science Center at Houston have discovered. [More]
Studies show how overactive immune response may contribute to heart disease in psoriasis patients

Studies show how overactive immune response may contribute to heart disease in psoriasis patients

Psoriasis is well-known for causing too many skin cells on elbows, knees, and across the body, but people living with psoriasis may also be at an increased risk of heart disease. [More]
PD-1 protein could serve as biomarker for predicting survival of lung cancer patients

PD-1 protein could serve as biomarker for predicting survival of lung cancer patients

The biomarker PD-1, a protein, could potentially be used to predict survival or disease-free survival of lung cancer patients who have had the tumour surgically removed. [More]
Researchers unveil new role of thymic dendritic cells in controlling T lymphocyte egress into the blood

Researchers unveil new role of thymic dendritic cells in controlling T lymphocyte egress into the blood

A team of scientists led by Julie Saba, MD, PhD at UCSF Benioff Children's Hospital Oakland, has unveiled a novel role of thymic dendritic cells, which could result in new strategies to treat conditions such as autoimmune diseases, immune deficiencies, prematurity, infections, cancer, and the loss of immunity after bone marrow transplantation. [More]
Study reveals new way to improve stability of common protein drugs

Study reveals new way to improve stability of common protein drugs

Gaining access to important biopharmaceuticals needed to treat illnesses and autoimmune diseases is one of the biggest obstacles developing countries face. [More]
Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Multiple sclerosis is an autoimmune disease in which the body's immune system attacks the patient's own cells. [More]
TUM scientists uncover molecular mechanisms of inhibitors that can selectively thwart immunoproteasome

TUM scientists uncover molecular mechanisms of inhibitors that can selectively thwart immunoproteasome

The immunoproteasome dismantles proteins and the resulting fragments are displayed on the surface of cells. This helps the immune system to recognize abnormal cells. However, in chronic inflammations and autoimmune diseases this “information channel” is overactive. [More]
Salk scientists discover key to amplification of ‘invader’ signals

Salk scientists discover key to amplification of ‘invader’ signals

When a receptor on the surface of a T cell -- a sentry of the human immune system -- senses a single particle from a harmful intruder, it immediately kicks the cell into action, launching a larger immune response. But exactly how the signal from a single receptor, among thousands on each T cell, can be amplified to affect a whole cell has puzzled immunologists for decades. [More]
Researchers gain new insights into how immune response size is controlled

Researchers gain new insights into how immune response size is controlled

Australian and Irish researchers have gained previously unachievable insights into how the size of our immune response is controlled, by developing new imaging and computational biology approaches to follow the behaviour of hundreds of cells. [More]
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